PLoS ONE
Articles in this Issue
Study of heterogeneity in immune responses to exposure in breast cancer: A protocol for a systematic review
Background Radiation is a treatment modality of interest in both palliative and curative settings for patients with breast cancer (BC). Despite many advances in radiation oncology, anti-radiation resi...
Fluorometric combination analysis of conformational changes in urea-induced unfolding of soybean protein isolates and their complexes with casein
Soybean proteins isolates (SPIs) could misfold to form amorphous aggregates after unfolding due to processing conditions, leading to a decrease in their solubility, and casein might be able to block t...
Effects of preoperative topical levofloxacin on conjunctival microbiome in patients undergoing intravitreal injections
Purpose Endophthalmitis is a serious eye infection that can occur after intravitreal injections. Topical antibiotics are frequently used as a preventative measure, but their impact on the conjunctiva...
Virtual reality-based training for radiopharmaceutical administration: development and educational effectiveness
In Japan, task shifting and sharing are promoted to reduce the workload of physicians. Radiological technologists have been assigned new responsibilities, such as securing venous access for radiopharm...
Correction: Development and validation of a cardiovascular risk prediction model for Sri Lankans using machine learning
Modeling spatial and temporal variability in educational development index of Bangladesh using socio-economic, and demographic data, 2001–2021: A Bayesian approach
Background The Educational Development Index (EDI) is a critical tool for assessing and tracking the progress of education systems from local to national, and even global scales and needs to be chosen...
PLANES: Plausibility analysis of epidemiological signals
Methods for reviewing epidemiological signals are necessary to building and maintaining data-driven public health capabilities. We have developed a novel approach for assessing the plausibility of inf...
Immunosuppressive drugs and diet interact to modify the gut microbiota and cardiovascular risk factors, and to trigger diabetes
Background Kidney transplant recipients are prescribed an immunosuppressive therapy (IST) and some of them follow a high fat diet (HFD) despite medical recommendations. Both are frequently associated...
Evaluating the accuracy of ICD-10 codes for syncytial respiratory virus diagnosis in hospitalized patients: A record-linkage study (2022–2023)
Background Respiratory Syncytial Virus (RSV) is a leading cause of severe respiratory infections in young children and older adults. Accurate RSV surveillance is essential to understanding its diseas...
Metabolic improvement after exercise training in children with obesity: Possible role of the six-minute walking test
The aims of this study are to evaluate the effectiveness of an online supervised training program in modulating lipid and glucose metabolism in children with obesity and to investigate the possible ro...
Correction: Effects of Yersinia pseudotuberculosis outer membrane vesicles on Pseudomonas aeruginosa antigens immune response
Extraordinary siblings: Mole rats, marmosets, and Radcliffe-Brown
According to the theory of kin selection, an organism that shows some level of altruism toward her kin – lowering her own fitness, raising that of a close genetic relative – may enjoy an evolutionary...
A quality improvement initiative to increase HIV post-exposure prophylaxis treatment for emergency department patients after sexual assault: A pre-post study
Background Many emergency department (ED) patients after a sexual assault face barriers to receiving HIV post-exposure prophylaxis (PEP). We implemented a quality improvement initiative which updated...
Associated factors, triggers and long-term outcome in Complex Regional Pain Syndrome (CRPS) in the upper limb – A descriptive cross-sectional study
The pathophysiology behind Complex Regional Pain Syndrome (CRPS) is not fully understood and associated factors and triggers for developing the condition are debated. We aimed to study such factors an...
Role of aspirin on colorectal cancer risk and bacterial translocation to bloodstream
An involvement of gut microbiota on the possible role of aspirin against intestinal adenoma (IA) and colorectal cancer (CRC) has been suggested. To further investigate this issue, we analyzed data fro...
Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms
To investigate the effect of pyrroloquinoline quinone (PQQ) on skin aging in the Bmi-1 KO mice and its underlying mechanisms, we administered a normal diet to both Wild type mice (WT) and Bmi-1 KO mic...
Correction: Detection and recognition of foreign objects in Pu-erh Sun-dried green tea using an improved YOLOv8 based on deep learning
The influence mechanism of planned behavior and self-consciousness on learners’ willingness to use language learning Apps: Validation based on structural equation modeling
The continuous development of digital technology facilitates the informatization of foreign language learning, making it possible to create a deeply integrated mobile learning environment which is con...
Genome-wide association and selection studies for pod dehiscence resistance in the USDA soybean germplasm collection
As a domestication trait, pod dehiscence has a pleiotropic effect on agronomic traits and significantly contributes to yield loss in soybean. Population studies are still required to comprehend the ge...
The impact of brominated flame retardants exposure on serum total bilirubin: A cross-sectional analysis
Background Brominated flame retardants (BFRs) are harmful, bioaccumulative, and persistent environmental pollutants, posing significant health risks. Elevated bilirubin levels can cause neurotoxicity...
Association between timing of exanthema subitum and febrile seizures: The Japan environment and children’s study
Recently, episodes of exanthema subitum (ES) have been occurring later than expected in Japanese patients, though the effects of this delayed timing remain unclear. Therefore, this study examined the...
Exploring Marine natural products as potential Quorum sensing inhibitors by targeting the PqsR in Pseudomonas aeruginosa: Virtual screening assisted structural dynamics study
Antibiotic resistance is a critical global health issue, and Pseudomonas aeruginosa is a particularly challenging pathogen. This gram-negative bacterium is notorious for its high virulence and resista...
Listeria monocytogenes infection in intestinal epithelial Caco-2 cells with exposure to progesterone and estradiol-17beta
Listeria monocytogenes (Lm) is a food-borne pathogen associated with serious pregnancy complications, including miscarriage, stillbirth, preterm birth, neonatal sepsis, and meningitis. Although Lm inf...
Efficient cutting stock optimization strategies for the steel industry
This study addresses a cutting stock problem in steel cutting industry by developing a mathematical model in which machine specifications and cutting conditions are constraints. The solution process i...
Investigating the influence of language teachers’ constructivist self-efficacy on their practice of constructivism in Ghanaian language and culture instruction
The education system in Ghana is undergoing a transition from a behaviorist instructional philosophy to a constructivist one, aiming to produce learners who can actively contribute to nation-building....