PLoS ONE
Articles in this Issue
Ecological properties of soil improved by high–performance ester materials under freeze–thaw cycles conditions
High-performance ester materials (HPEMs) are widely applied in slope soil restoration owing to their biodegradability, with a predictable degradation cycle of 2–3 years. Although HPEMs have been exten...
Association between 2D landing biomechanics, isokinetic muscle strength and asymmetry in females using novel, task specific metrics based on ACL injury mechanisms
This study investigated the relationship between isokinetic muscle strength metrics, landing biomechanics, and their asymmetries, in females. Twenty-three female team sport athletes completed unilater...
Clinico-pathological and treatment characteristics of HIV and non-HIV related vulvar cancers: Analysis of a South African cohort
Objective The main objective of this study was to describe the clinical, pathological and treatment characteristics of patients with vulvar cancer who had surgery and or radiotherapy at Steve Biko Aca...
Front-edge erosion impact on landslide stability: A multi-scale monitoring and numerical simulation case study
Airborne LiDAR enables large-scale landslide displacement field monitoring, yet suffers from complex error sources and lower accuracy than contact measurements. While GPS offers higher precision, it f...
Nonlinear variations and drivers of vegetation NPP on the Tibetan Plateau: Interaction of natural and human factors
Understanding the drivers of changes in vegetation net primary productivity (NPP) is critical for comprehending ecosystem dynamics and their ability to respond to environmental shifts. However, the co...
Insecticidal potential of five medicinal plants: An In Vitro evaluation and molecular docking analysis of Artemisia absinthium
The Kashmir range of North-Western Himalayas harbours a large number of medicinal plants that have insecticidal, antifeedent or insect repellent properties. Herein, we evaluated the insecticidal activ...
School food and nutrition environments in Australian primary schools: A scoping review
Schools are a key environment which can provide access to food, education and skills to enhance food and nutrition literacy and health and wellbeing of primary school students. This review set out to...
Exploring visitor perception and environmental element relationships in rock carving landscapes through random forest analysis
As a typical representative of cultural landscapes, the perceptual assessment of rock carvings encompasses not only the artistry of the carvings themselves but also the multi-dimensional impact of the...
Usability of machine learning algorithms based on electronic health records for the prediction of acute kidney injury and transition to acute kidney disease: A proof of concept study
Background Acute kidney injury (AKI) and acute kidney disease (AKD) are frequent complications of hospitalization, resulting in reduced outcomes and increased cost burden. However, these conditions ar...
A test method for selecting suitable cleaning indicators for routine cleaning monitoring on a washer-disinfector in a central sterile supply department
Cleaning indicators are widely used to evaluate the efficacy of cleaning processes in automated washer-disinfectors (AWDs) in healthcare settings. In this study, we systematically analyzed the perform...
Fabrication and appraisal of axitinib loaded PEGylated spanlastics against MCF- 7 and OV- 2774 cell lines using molecular docking methods and in-vitro study
Axitinib is a second-generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of actio...
A sticky Poisson Hidden Markov Model for solving the problem of over-segmentation and rapid state switching in cortical datasets
The application of hidden Markov models (HMMs) to neural data has uncovered hidden states and signatures of neural dynamics that are relevant for sensory and cognitive processes. However, training an...
Developing a national code of ethics for pharmacists in Kuwait: Insights from a survey and a modified Delphi study
Background Pharmacists play a crucial role in healthcare and are expected to uphold high ethical standards. Establishing a code of ethics for pharmacists is essential as it supports improved patient o...
Epidemiological trends of urolithiasis in working-age populations: Findings from the global burden of disease study 1990–2021
Background One of the most prevalent urinary disorders worldwide, urolithiasis has symptoms and a high rate of recurrence. It has placed a significant strain on the global economy and health care syst...
Mixed-methods study to assess delay among patients with tuberculosis in an urban setting of Bangladesh
Background Tuberculosis (TB) regained its position as the leading cause of death globally from a single infectious disease agent in 2024. Delayed diagnosis and treatment hamper effective TB control. W...
Imidacloprid decreases energy production in the hemolymph and fat body of western honeybees even though, in sublethal doses, it increased the values of six of the nine compounds in the respiratory and citric cycle
Background Neonicotinoids, including imidacloprid (IM), cause harm to Apis mellifera in a number of ways, among others by impairing body maintenance, resistance and immunity. Energy resources are impo...
The modeling and condition analysis of nondestructive testing based on ESPI for internal defects of materials
Electronic speckle pattern interferometry (ESPI) is a non-contact, full field, real-time measurement technology, which judges the position and size of the internal defects of the object through the ex...
Sequence–lithofacies paleogeographic evolution and its control on deep and ultra–deep reservoir types: A case study of the Permian Maokou Formation in northeastern Sichuan Basin
The Middle Permian Maokou Formation in northeastern Sichuan Basin has been explored with continuous breakthroughs in recent years, but its sequence–lithofacies paleogeographic characteristics and tect...
Investigation on the bond-slip behavior of recycled aggregate concrete-filled steel tube with studs
This study investigates the influence of built-in studs on the bond behavior in recycled aggregate concrete-filled steel tube (RACFST) composite structures through push-out experiments. The effects of...
Using the node importance of patent network to evaluate patent relational value
Citation serves as a common and considerable metric for evaluating the relational value between patents and technologies. This relational value, generally, can be measured by the centrality of the pat...
Identification of digital clinical decision support systems for supporting diagnosis and triage of patients with shoulder disorders: A scoping review protocol
Background Clinical decision support systems (CDSSs) are computerized tools that support clinical decision-making processes. Primary care decision-making is complex and has the potential to influence...
Association of prior opium addiction with incident non-alcoholic fatty liver disease: A case-control study
Background Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition with no approved pharmacological treatments. Given opium’s potential metabolic effects on lipid profiles, bl...
Performance management and development system in South Africa, a necessary evil: Qualitative study
Performance management focused on development enhances individual and organisational performance and enables improved services. Achieving performance management objectives is vital for addressing heal...
Data augmentation of time-series data in human movement biomechanics: A scoping review
Background: The integration of machine learning and deep learning methodologies has transformed data analytics in biomechanics. However, the field faces challenges such as limited large-scale data set...
Effects of COVID-19 convalescence on pregnancy outcomes in frozen-thawed embryo transfer: A retrospective cohort study
In this study, we aimed to examine whether frozen-thawed embryo transfer during the recovery period after coronavirus disease can affect treatment outcomes. This population-based retrospective cohort...