PLoS ONE
Articles in this Issue
Impact of gender, lunge direction, and fatigue on the lower limb biomechanics in badminton lunges
Background The lunge is a crucial movement in badminton, influenced to different extents by factors such as lunge direction, fatigue, and gender. This study investigates the effects of these factors o...
Biology exams rarely use visual models to engage higher-order cognitive skills
Visual models are a necessary part of molecular biology education because submicroscopic compounds and processes cannot be directly observed. Accurately interpreting the biological information conveye...
Implementation and enforcement of mandatory calorie labelling regulations for the out-of-home sector in England: Qualitative study of the experiences of business implementers and regulatory enforcers
Background Mandatory calorie labelling on menus of large out-of-home food outlets was implemented in England on 6 April 2022. Barriers and facilitators that were unforeseen before...
Correction: Impact of non-invasive oxygen reserve index versus standard SpO2 monitoring on peripheral oxygen saturation during endotracheal intubation in the intensive care unit: Protocol for the randomized controlled trial NESOI2
PLZF promotes compensatory lung growth by increasing HPMEC proliferation and angiogenesis
Angiogenic signaling pathway activation has been shown to accelerate compensatory lung growth (CLG) after unilateral pneumonectomy (PNX). Therefore, studying specific genes regulating angiogenic signa...
Depressive and anxiety symptoms, and their associated factors among adult, visually impaired follow-up patients attending the Hawassa University Comprehensive Specialized Hospital Eye Care and Training Center, South Ethiopia, 2024
Background Although the burden of depressive and anxiety symptoms among visually impaired adults has become a serious current health issue, relatively little is known in the study setting and in Ethio...
Coupling coordination between agricultural carbon emission efficiency and food security in China: The spatial-temporal evolution and prediction
Addressing climate change and food insecurity is crucial for achieving the Sustainable Development Goals (SDGs), with the enhancement of Agricultural Carbon Emission Efficiency (ACEE) and the assuranc...
Financing drug development via adaptive platform trials
We propose a new approach to funding disease-specific drug development via a variation of the adaptive platform trial. This trial is designed to test a portfolio of drug candidates in parallel, with t...
Proteome remodeling in the zoospore-to-vegetative cell transition of the stramenopile Aurantiochytrium limacinum reveals candidate ectoplasmic network proteins
Thraustochytrids are marine protists of ecological and biotechnological importance. Like many other eukaryotes, their life cycle includes a critical transition from a flagellated, swimming zoospore di...
The impact of music industry digitalisation on population well-being: Empirical evidence from China
With the profound transformations brought about by digital technology in the global economy and social operations, digital music has emerged as a vital medium for meeting residents’ cultural needs, pl...
Maternal gut microbiome interventions to improve maternal and perinatal health outcomes: Target product profile expert consensus and pipeline analysis
Objective To develop a novel Target Product Profile (TPP) outlining the minimum and optimal requirements of probiotics targeting the maternal gut microbiome, create a research and development (R&D...
A multi-center trial-based economic evaluation of the SELF-program: A function-focused care program for nursing staff providing long-term care for geriatric clients in nursing homes compared to care as usual
Introduction This study aims to evaluate the cost-effectiveness and cost-utility of the SElf-reliance, autonomy, Life quality, and Functionality-program (SELF) for nursing staff in nursing homes who p...
Study on the extraction and stability of total flavonoids from Millettia speciosa Champ
Millettia speciosa Champ, a member of the Leguminosae family and the genus Millettia, is a rich source of total flavonoids. Investigating the extraction methods and stability of total flavonoids from...
Vulnerable connectivity caused by local communities in spatial networks
Local communities by concentration of nodes connected with short links are widely observed in spatial networks. However, how such structure affects robustness of connectivity against malicious attacks...
DMSU-Net++: A dual multiscale retinal vessel segmentation method based on improved U-Net++
Retinal blood vessels are of different sizes and shapes, and even contain very fine capillaries with complex structural morphology, making accurate segmentation a difficult task. To address the above...
Educational improvement through machine learning: Strategic models for better PISA scores
In this study, in addition to traditional variables such as economic wealth or the number of books read, on which many studies have already been conducted, variables that are thought to influence stud...
Driving innovation: When design collaboration becomes open source, how do reward mechanisms and in-process feedback act as catalysts
Open innovation, prevalent in projects like design crowdsourcing, is widely acknowledged for its role in advancing technology through knowledge flow. However, the competitive nature of design teams of...
Towards real-world monitoring scenarios: An improved point prediction method for crowd counting based on contrastive learning
In open environments, complex and variable backgrounds and dense multi-scale targets are two key challenges for crowd counting. Due to the reliance on supervised learning with labeled data, current me...
Determinants of condom use among sexually active youth in SBC intervention communities in Tanzania: A cross-sectional study
HIV and unplanned pregnancies are significant public health concerns for youth in Sub-Saharan Africa. Consistent condom use is an effective behavioral method in preventing both health outcomes; howeve...
Association between atherogenic index of plasma and depression in premenopausal and postmenopausal women: A cross-sectional study
Aim This study is the first to investigate the association between the Atherogenic Index of Plasma (AIP) and depression in women, stratified by menopausal status. Methods A total of 9,060 subjects w...
Emotional attachment and resistance to change in the use of technology: A study among Chinese university music teachers
While technology adoption has received widespread attention in teaching, little research has been conducted on the impact of emotional attachment and resistance to change on technology adoption by tea...
How much we express love predicts how much we feel loved in daily life
Feeling and expressing love in daily life are interconnected and perhaps mutually influential experiences. In this study we examined the reciprocal dynamics of feeling and expressing love and its rela...
Comparative analysis of skin microbiome of patients with filarial lymphedema and healthy individuals
Background Lymphatic filariasis, a vector borne parasitic disease is a public health problem in the tropical region. Recurrent skin and soft tissue infections termed adenolymphangitis (ADL) is a major...
Design, synthesis, and biological activity of novel halogenated sulfite compounds
The acaricide propargite has been widely used for over 50 years without significant resistance issues. Addressing to the propargite defects of poor crop safety, thirty-six novel halogenated propargite...
Changes in radiocarpal and intercarpal arthrodesis incidence in Sweden: A 16-year retrospective analysis of 5 189 surgeries
Radiocarpal and intercarpal arthrodesis are common procedures for managing advanced arthritis, post-traumatic conditions, and failed interventions. This observational study analysed 5,189 cases of art...