PLoS ONE
Articles in this Issue
Behind political affiliation: How moral values, identity politics, and party loyalty have affected COVID-19 vaccination
Falling short of its vaccination goals, the United States faced a critical challenge in ending the pandemic, with political partisanship emerging as a barrier to COVID-19 vaccination uptake. This stud...
Corporate financial distress prediction with multiperiod annual report data: A fusion deep neural network model
The occurrence of financial distress in enterprises not only leads to operational difficulties but also may trigger chain reactions such as bankruptcy, debt arrears, layoffs, etc., which in turn have...
Season, wind speed, and seasonal rain are major drivers of a regional aeolian sediment transport model
Wind erosion and sediment transport continue to increase in many parts of the world, leading to decreased soil quality, accelerated snow-melt, respiratory diseases, and traffic accidents. The processe...
Anti-cancer compound screening identifies Aurora Kinase A inhibition as a means to favor CRISPR/Cas9 gene correction over knock-out
CRISPR gene therapy holds the potential to cure a variety of genetic diseases by causing a targeted DNA break, which is repaired by host DNA damage responses. One option to introduce precise gene corr...
Factors associated with wasting among pediatric cancer patients aged 2–17 years at Uganda cancer institute: A cross-sectional study
Introduction Wasting is a major concern among pediatric cancer patients and significantly affects treatment outcomes and quality of life. However, limited data exist on the prevalence of wasting and i...
Perspectives of teachers of students with intellectual disabilities on the role of educational policies and systems in using Universal Design for Learning: A qualitative study
Universal Design for Learning is among the inclusive frameworks that has been incorporated in policies such as the “Every Student Succeeds Act of 2015” and the “Higher Education Opportunity Act of 200...
Synthesis of novel phenoxyacetohydrazide compounds and evaluation therapeutic potential exhibit as anti-inflammatory and anti-angiogenic
This study aimed to design, synthesize, and evaluate novel morpholine-substituted phenoxyacetohydrazide derivatives as potential anti-inflammatory and anti-angiogenic agents. The compounds were synthe...
Association between cardiometabolic risk factors and multidrug-resistant tuberculosis: A case-control study
Background Multidrug-resistant tuberculosis (MDR-TB) continues to be a major public health concern, especially in high-burden countries like Nepal. While individual risk factors are known, the cumulat...
Study protocol for a systematic review with meta-analysis to compare digital stress tests regarding their psychological and physiological stress responses
Background and aim Stress is a phenomenon of everyday life that all humans are exposed to, and that can have negative effects on health. Exposure to chronic stress has been associated with development...
Correction: Lack of variations in the salamander chytrid fungus, Batrachochytrium salamandrivorans, at its alleged origin: Updating its Japanese distribution with new evidence
Perceived cancer-related stigma among Arab patients: A cross-sectional study
Purpose The primary objective of this study was to examine the perceived stigma experienced by patients with cancer within the context of Arabic and Islamic culture. Methods A cross-sectional study...
UMOT: A unified framework for long- and short-term association for multi-object tracking
Multi-object tracking (MOT) is an important research direction in the field of computer vision, but it often leads to problems such as trajectory breakage and identity switches in complex scenarios du...
Research on the impact mechanism of digital technology on the new-quality productivity of port logistics
The development of port digital technology is an important way to promote the development of new-quality productivity in port logistics. This study takes Ningbo Port, Shanghai Port, and Tangshan Port...
Research on optimization of transportation routes for infectious medical waste
During the pandemic, the amount of infectious medical waste has increased dramatically. Currently, the medical waste recycling process generally suffers from defects such as long distances, high costs...
Genetic drivers of liver cirrhosis: The role of SERPINA1 and PNPLA3 variants in disease onset and progression
SERPINA1 Z and PNPLA3 G alleles are the most potent genetic risk modifiers in chronic liver disease (CLD) progression. We aimed to test the impact of concomitant carriage of these variants on the prog...
Transcriptome differentiation in Cryptomeria japonica trees with different origins growing in the north and south of Japan
Cryptomeria japonica is a coniferous species widely distributed throughout Japan and is therefore adapted to a variety of environments. To identify genes involved in its local adaptation, individuals...
The effect of gamma irradiation on the stability of vitamin D in select finfish species
Finfish are an excellent source of dietary vitamin D and additional nutrients. Accordingly, their global consumption has increased. To meet this demand, finfish are now imported across large geographi...
Observation and simulation of chemically mediated searches in marine zooplankton
Chemical communication is one of the most important capabilities of zooplankton, yet it remains understudied. We report observations of marine parasitic isopods Gnathia marleyi and coral larvae Orbice...
Role of community pharmacists in the safe and effective use of complementary and alternative medicine in the Middle East: A scoping review
Background Community pharmacists (CPs) play a crucial role in promoting safe use of Complementary and Alternative Medicine (CAM). This scoping review examined existing evidence on the role of CPs in C...
Evaluating the cost-effectiveness of COVID-19 mRNA primary-series vaccination in Qatar: An integrated epidemiological and economic analysis
Qatar implemented a mass primary-series vaccination campaign to mitigate the impact of the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to retrospectively evaluate the cost-effective...
Cost-effectiveness analysis of benmelstobart and anlotinib plus chemotherapy versus standard chemotherapy in first-line treatment for extensive-stage small cell lung cancer: Perspectives from the United States and China
Background Benmelstobart combined with anlotinib and chemotherapy has demonstrated significant clinical advantages in extending progression-free survival and overall survival compared to chemotherapy...
Regulatory influence of α-Pinene on MATN3 expression in hepatocellular carcinoma: Extending to pan-cancer analysis
In the search for novel therapeutic strategies against cancer, natural compounds such as α-Pinene, a bioactive monoterpene predominantly found in coniferous trees, have emerged as potential modulators...
Unlocking insights from complex data: Leveraging heat maps for decision-making in LMIC
Introduction In low- and middle-income countries (LMICs), health outcomes are often constrained by inadequate or misdirected resource allocation and limited access to services such as contraception an...
Modeling the detection range of pulsed calls from resident killer whale in nearshore waters of British Columbia, Canada
Passive acoustic monitoring (PAM) using underwater listening stations is widely employed to assess the presence and movements of marine mammals. Accurate interpretation of PAM data requires knowledge...
Automatic road damage recognition based on improved YOLOv11 with multi-scale feature extraction and fusion attention mechanism
Rapid urbanization and growing traffic volumes have increased the demand for efficient and accurate road damage detection to ensure traffic safety and optimize maintenance. Traditional manual and vehi...