PLoS ONE
Articles in this Issue
Cardiac implantable electronic devices’ longevity: A novel modelling tool for estimation and comparison
Aims Generator longevity is the key issue for patients, and is also important for payers, yet implanters of Cardiac Implantable Electronic Devices (CIEDs) face a challenge when selecting the appropria...
Does financial compensation matter for research participation in prevention trials in Tanzania? Perspectives of healthy volunteers
Background Financial compensation is an important aspect of respect for people enrolled in clinical research, yet continues to raise ethical questions. Respondents’ characteristics, shaped by contextu...
Comprehensive analysis of the influence of loess structure on strength on the Loess Plateau, China
This study examines the influence of loess structure on strength by selecting three representative regions of the Loess Plateau in northern Shaanxi as the research area. Malan loess serves as the test...
The efficacy of modified bloodless del Nido cardioplegia in isolated aortic valve replacement
This study aimed to evaluate the safety and efficacy of a modified, bloodless Del Nido (DN) cardioplegia solution in patients undergoing isolated aortic valve replacement (AVR). A total of 370 patient...
Enhancing nursing students’ patient-centeredness attitudes and emotional skills through co-teaching with patients and caregivers: A mixed-methods study
The objective of this study is to evaluate changes in patient-centeredness attitudes, empathy, and emotional intelligence among nursing students trained with patients and caregivers as co-teachers. A...
Potential geographical distribution of Garcinia paucinervis Chun et How in China under future climate change scenarios based on the MaxEnt Model
Garcinia paucinervis Chun et How is a tree species with important ecological, medicinal, and ornamental value. Studying the impact of climate change on the potential distribution of this species offer...
The validity and reliability of the Dutch version of the Student Satisfaction and Self-Confidence in Learning Scale (SCLC) for pharmacy technicians
Background The Student Satisfaction and Self-Confidence in Learning Scale (SCLC) is widely used to measure satisfaction and self-confidence in learning. The 13-item scale includes two subscales: satis...
The impact of the COVID-19 pandemic on public trust in science
Public trust in science plays a critical role in shaping attitudes toward health policies, technological advancements, and societal progress. The COVID-19 pandemic profoundly influenced science commun...
Correction: Enhanced DWT-OFDM communication system using wavelet domain equalizer with Co-CFO
Physical activity is associated with exercise capacity among patients undergoing chemotherapy: A pilot randomized controlled trial
Introduction Exercise intolerance is common among cancer patients undergoing active treatments. We conducted a pilot study in patients receiving potentially cardiotoxic therapies to investigate the im...
Structure-aware medical image fusion via mean curvature enhancement in the contourlet domain
The medical image fusion is a critical application in medical diagnosis, where anatomical and functional information from different imaging modalities, e.g., Magnetic Resonance Imaging (MRI) and Compu...
The role of DAAO in cognitive impairment of offspring mice induced by arsenic exposure during early developmental stage
Arsenic exposure model of offspring mice was established and intervened with 6-chlorobenzo[d]isoxazol-3-ol (CBIO), a D-amino acid oxidase (DAAO) inhibitor, to explore the role of DAAO in cognitive imp...
Enhanced calibration method for wall-mounted RGSC cameras: Mitigating baseline drift caused by CT couch sagging
Purpose The drift signal due to CT couch sagging introduces intrinsic noise into respiratory signals, impairing the accuracy of tumor motion management. The purpose of this work is to present an enhan...
Long-term functional rescue of trauma-induced vision loss by a novel, small molecule TrkB modulator
Brain-derived neurotrophic factor (BDNF) signaling through the tropomyosin-related kinase B (TrkB) receptor promotes neuronal growth and survival following an injury. However, its short half-life and...
Correction: Toward mapping pragmatic impairment of autism spectrum disorder individuals through the development of a corpus of spoken Japanese
Association between traditional fermented milk (mursik) consumption and oesophageal carcinoma among patients presenting to two referral hospitals in Nandi County, Kenya: A case-control study
Background Oesophageal carcinoma (OC) is a prominent cause of morbidity and mortality in low and middle-income countries yet little evidence exists about its contextual drivers. The objectives of this...
In-person social isolation in the age of smartphones: Examining age, period, cohort effects by gender
Objectives The rise of smartphones and social media is widely seen as a pivotal societal shift that has fueled what the U.S. Surgeon General in 2023 described as “our epidemic of l...
Constructing a digital twin maturity assessment framework for the building construction phase based on an improved matter-element model: A case study of a construction project in Xinyang, China
Digital twin technology has the potential to enhance construction efficiency, reduce costs, and minimize errors. However, its application during the construction phase remains at an early stage, large...
Oral bowel cleansers and ischemic colitis risk: A real-world disproportionality analysis
Background Ischemic colitis (IC) is a serious but underrecognized complication potentially associated with bowel preparation. While previous studies have reported sporadic cases, the true frequency an...
Correction: Blockchain-based zero trust networks with federated transfer learning for IoT security in industry 5.0
Machine learning-based transcriptomic analysis identifies NAMPT and SAT1 as potential biomarkers and therapeutic targets in ferroptosis-associated rheumatoid arthritis
Background Rheumatoid arthritis (RA) is an autoimmune disease with chronic presentation, involving symmetric joints and systemic involvement. Ferroptosis is iron-dependent programmed cell death throug...
The Founders’ 400 and Chicago Perinatal Origins of Disease study protocol: Following a prospective, longitudinal cohort from early pregnancy through two years of postnatal life
Introduction The primary aim of the Chicago Perinatal Origins of Disease (CPOD) study is to characterize social, environmental, and biological exposures from early pregnancy through two years of postn...
Design and evaluation of a blended basketball training program using the ADDIE model
This study aimed to develop and evaluate a blended learning basketball training program for university students based on the ADDIE instructional design model. A quasi-experimental one-group pre-test–p...
Inequities in breast cancer outcomes in Chile: An analysis of case fatality ratios and survival rates (2007–2018)
Breast cancer is a leading cause of illness and death among women in Chile, yet national data on health outcomes remain limited in the absence of a cancer registry. This observational study examines d...
An inertial sensor-based comprehensive analysis of manual wheelchair user mobility during daily life in people with SCI
This study employed three inertial measurement units to quantify the mobility characteristics of 12 manual wheelchair users with spinal cord injuries (SCI) over 7 consecutive days, revealing nuanced p...