PLoS ONE
Articles in this Issue
A qualitative evaluation of a compassion-focused therapy group intervention for UK healthcare staff at an acute hospital trust
Healthcare staff can encounter empathy distress, burnout, and trauma, often responding with self-criticism rather than self-compassion, yet there remains limited evaluation of compassion-focused inter...
Correction: C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient
Olfactory bulbectomy-induced impairment of lipid utilization leads to abnormal glucose metabolism in mice
Increased lipid utilization after food odor perception is a recently identified Pavlovian cephalic phase response in fasted mice that serves to prevent diet-induced glucose intolerance. However, the i...
Mathematically modeling worried-well behavior during infectious disease outbreaks
Although curtailing pathogen spread is critical for mitigating the impact of novel infectious disease outbreaks, addressing the psychological and social responses of populations is also important. Thi...
Evaluating the effects of synthetic POM cycles and NAD+ kinase expression on fatty alcohol production in Saccharomyces cerevisiae
Efficient regeneration of NADPH can be a limiting factor for anabolic processes in engineered microbial cells. We tested the ability of four distinct Pyruvate-Oxaloacetate-Malate “POM” cycles composed...
A review of the genus Angilia Stål, 1865 (Hemiptera: Heteroptera: Veliidae): New species, new synonyms, checklist, and key to species
Angilia Stål, 1865 is one of three genera of the subfamily Veliinae (Hemiptera: Heteroptera: Veliidae) from the Eastern Hemisphere and is distributed in sub-Saharan Africa, Madagascar, and Southeast A...
Diabetes-related distress and associated factors among adult diabetes mellitus patients attending public hospitals in Gedio zone, southern Ethiopia: Mediation analysis
Background Individuals with diabetes might experience distress due to their treatment regimen, interactions with physicians, interpersonal relationships, and emotional well-being. This may lead to low...
Impact of dietary salicylates on angiogenic factors and biochemical parameters in a rat model of preeclampsia
Background The pathophysiology of preeclampsia involves impaired cytotrophoblastic invasion, placental ischemia, inflammation, and angiogenic imbalance. Prophylactic low-dose aspirin can reduce the ri...
Alzheimer’s disease classification using a hybrid deep learning approach with multi-layer U-net segmentation and XAI driven analysis
Alzheimer’s disease (AD) is a neurodegenerative illness causing a significant decrease in cognitive function, and early, accurate diagnosis is of great therapeutic and diagnostic value. Currently, the...
Robustness of inferences in risk and time experiments to lifecycle asset integration
Experiment participants can engage in unobservable asset integration, mentally incorporating non-experimental “field” resources into an ostensibly controlled scenario. We extend asset integration to i...
Creep model of roadway surrounding rock considering hardening effect and damage effect
The influence of confining pressure on creep characteristics was analyzed by carrying out creep tests of rocks under different confining pressures. A new creep model of roadway surrounding rock consid...
User acceptability profiles of vaginal treatments among women with genitourinary syndrome of menopause
Background This study aimed to identify patient segments of acceptability to vaginal dosage forms in women with the genitourinary syndrome of menopause and to identify the most important predictors an...
“Hills of Activity” as an effective method for mitigating ground surface vibration in sustainable residential development
This paper investigates the vibration mitigation efficiency of a hill and a system of hills. The effects of obstacle height, slope inclination angle, the number of embankments used, and their shape on...
Predicting chromatin conformation contact maps
Over the past 15 years, a variety of next-generation sequencing assays have been developed for measuring the 3D conformation of DNA in the nucleus. Each of these assays gives, for a particular cell or...
New estimates of the costs of adverse events in patients with cancer
The cost of adverse events (AEs) is a critical component of healthcare economic models for cancer treatment; however, few comprehensive estimates of these costs exist. Previous studies focused on cost...
Estimating heterogeneous impacts Of subsidised health insurance: A causal machine learning approach
The evaluation of social and health policies often necessitates understanding the variations in impacts based on recipients’ observed characteristics, underscoring the value of estimating treatment ef...
COVID-19 vaccine hesitancy and its predictors among healthcare workers in a tertiary hospital in Ghana: A cross-sectional survey
Background Vaccination is one of the most effective public health interventions, but its hesitancy still poses a challenge in achieving acceptable coverage. This study was designed to assess the level...
The impact of biofertilizer technology adoption on the faba bean productivity in the central highlands of Ethiopia: The propensity score matching model
Adoption of organic fertilizer technology increases crop productivity through replenishing the soil with natural organic nutrient as compared to in-organic chemical that is costly and damaging the soi...
Dual S-methoprene and Lysinibacillus sphaericus larvicide use leads to multiple independent, and not cross-resistance in Culex pipiens
S-methoprene, an insect growth regulator, and Lysinibacillus sphaericus (Ls), an entomopathogenic bacterium, are important larvicides used to control Culex pipiens [L.] mosquitoes, the primary vector...
Association between food insecurity and mental health outcomes among a convenient sample of Lebanese pregnant women
Food insecurity (FI) is a pressing public health challenge, suggested to be associated with psychological distress and detrimental effects, especially in vulnerable populations such as pregnant women....
Orientation selectivity properties for integrated affine quasi quadrature models of complex cells
This paper presents an analysis of the orientation selectivity properties of idealized models of complex cells in terms of affine quasi quadrature measures, which combine the responses of idealized mo...
Advancing person-centered care: Protocol for quality measurement and management (QM2) in the New York State system for opioid use disorder treatment
Introduction The United States is facing an opioid use disorder (OUD) epidemic, marked by unprecedented overdose death rates. In New York State, synthetic opioids significantly contribute to the incre...
Hatching-Box: Automated in situ monitoring of Drosophila melanogaster development in standard rearing vials
In this paper we propose the Hatching-Box, a novel in situ imaging and analysis system to automatically monitor and quantify the developmental behavior of Drosophila melanogaster in standard rearing v...
Correction: Probiotics attenuate valproate-induced liver steatosis and oxidative stress in mice
Insulin resistance markers HOMA-IR, TyG and TyG-BMI index in relation to heart failure risk: NHANES 2011-2016
Background Insulin resistance (IR) is increasingly recognized as an important factor in the development of heart failure (HF). This study aimed to evaluate the association and predictive ability of th...