PLoS ONE
Articles in this Issue
Performance of large language models ChatGPT and Gemini in child and adolescent psychiatry knowledge assessment
Objective This study evaluates the performance of four large language models—ChatGPT 4o, ChatGPT o1-mini, Gemini 2.0 Flash, and Gemini 1.5 Flash—in answering multiple-choice questions in child and ado...
A move in the right direction: Tracking the traceability of British Thoroughbreds outside of racing
Horse welfare within/after racing is often questioned by the public. British Racing’s Horse Welfare Board’s “A life well-lived” strategy provides a blueprint for Thoroughbred welfare, advocating accur...
Health effects of occupational noise exposure on heavy-duty equipment operators and exposed workers in a mining firm in Ghana
Background The mining industry is one of the sectors that uses heavy-duty equipment in its daily operations. This exposes miners to undesirable noise levels, increasing their risks of health-related p...
Detection and score grading for prostate adenocarcinoma using semantic segmentation
Prostate cancer is a major global health challenge. In this study, we present an approach for the detection and grading of prostate cancer through the semantic segmentation of adenocarcinoma tissues,...
Measurement properties of instruments used to measure health-related quality of life in pediatric and adults patients with inherited epidermolysis bullosa: A systematic review and meta-analysis protocol
Inherited Epidermolysis Bullosa (EB) is a group of rare, genetic skin diseases characterized by extreme fragility of the skin and mucous membranes, leading to blistering and wounds in response to mini...
Investigating the use of physics informed neural networks for dam-break scenarios
The real-time forecasting of flood dynamics is a long-standing challenge traditionally addressed through numerical solutions of the Shallow Water Equations (SWEs). Numerical solutions of realistic flo...
Experimental exploration of artificial intelligence and ADAMS simulation technology in the teaching of vertical hoop upward throw in rhythmic gymnastics
Currently, rhythmic gymnastics teaching mainly focuses on traditional techniques and cannot break through issues such as blind spots in the coordination training between apparatus and body. In the aca...
Significant increase in eco-efficiency of China’s grain production from 2000 to 2022: Trend changes, typological evolution, and driving factors
Enhancing the eco-efficiency of grain production is a critical avenue for ensuring food security and ecological sustainability. This study employs a global super-efficiency SBM model incorporating und...
Work engagement and its association with emotional intelligence and demographic characteristics among nurses in Palestinian neonatal intensive care units
Introduction Work engagement, defined as a positive, fulfilling, work-related state of mind characterized by vigor, dedication, and absorption, is crucial for nurse retention and quality of care in hi...
Policy landscape analysis for fruits and vegetables in four low- and middle-income countries through a food systems approach
Low fruit and vegetable intake is a significant nutritional issue in low- and middle-income countries, where resolving all forms of malnutrition remains a pressing challenge. Nutritional status is inf...
Sustainable heavy metal immobilization in contaminated soils using plant-derived urease-driven biomineralization
Soil contamination by heavy metals presents substantial ecological and geotechnical risks, thereby demanding sustainable remediation strategies. Conventional approaches, including chemical stabilizati...
Confidence, animal spirits, and the macroeconomy in China: Based on mixed-frequency data models
This paper employs the mixed-frequency Granger causality test, reverse unconstrained mixed-frequency data sampling models, and Chinese data from January 2006 to June 2024 to test the nexus between con...
Analysis of global, regional and national trends in the burden of soft tissue and other extraosseous sarcomas from 1990 to 2021: A systematic analysis of the global burden of disease study 2021
Background Soft tissue and other extraosseous sarcomas (STSES) are rare malignant tumors originating from mesenchymal tissues with complex etiologies. A systematic analysis of global burden trends is...
Correction: Chemical profile and analysis of biosynthetic pathways and genes of volatile terpenes in Pityopsis ruthii, a rare and endangered flowering plant
Utility of enhanced recovery after surgery protocols in reducing postoperative opioid use across different surgical specialties—An analysis of Iowa’s billion pill pledge program
Introduction The opioid epidemic in the United States poses a major public health challenge, particularly in the context of surgery and perioperative pain management. This study examines the effective...
Remote physical function testing in older adults: a mixed methods study exploring test reliability, feasibility, and perceptions of participants and assessors
Impaired physical function is linked to poor health outcomes in older adults. Low-cost, remote strategies for monitoring physical function could enable timely interventions, improving health and reduc...
Development of a novel eye drop aid and evaluation of its efficacy
Purpose The aim of this study was to develop a new eye drop aid and investigate its efficacy in glaucoma patients. Methods The developed eye drop aid is compatible with most therapeutic eye drops an...
Structural stability-guided scaffold hopping and computational modeling of tankyrase inhibitors targeting colorectal cancer
Colorectal cancer is one of the leading causes of cancer-related deaths worldwide, mainly due to aberrant Wnt/β-catenin signaling resulting from APC mutations. Tankyrase is a key regulator of this pat...
Differential expression and regulation of FASLG by miR-5195/miR-3941 in age-related hearing loss
Presbycusis, or age-related hearing loss (ARHL), is a progressive condition that involves a steady decline in auditory function, primarily caused by the physiological alterations that occur with aging...
Molecular mechanisms of dragon’s blood in treating ulcerative colitis based on NF-κb/NLPR3/Caspase-1 pyroptosis signaling pathway
Objective To elucidate the molecular mechanism of dragon’s blood (DB) in the treatment of ulcerative colitis (UC). Methods Bioactive metabolites of DB absorbed into the bloodstream were characterize...
Effects of sprint interval training compared to high intensity interval training on repeated sprint capacity and sport-specific performance in college-aged male tennis players
Purpose This study compared the effects of sprint interval training (SIT) versus high-intensity interval training (HIIT) on repeated sprint capacity and sport-specific performance in male tennis playe...
Spatial distribution of chickpea ascochyta blight (Ascochyta rabiei) and analyses of biophysical factors influencing disease epidemics in northwestern Ethiopia
Chickpea (Cice rarietinum L.) is one of the important grain legume crops in Ethiopia, which serves as a source of both foreign exchange and food. However, the crop production and productivity are curr...
Improving segmentation precision in prostate cancer adaptive radiation therapy with a patient-specific network
Adaptive radiotherapy (ART) enhances prostate cancer treatment by accounting for daily anatomical variations, but clinical implementation remains limited due to the need for accurate and efficient aut...
Efficacy and outcomes of surgical staples as an alternative to conventional skin closure in canine mastectomy
Surgical wound closure is critical in oncologic surgeries and directly influences healing, postoperative complications, and recovery time. In canine mastectomies, conventional skin closure with nylon...
Effects of chitosan oligosaccharide on the growth performance, antioxidant capacity, immune function, intestinal digestive capacity and morphological structure in growing female minks
This study aimed to investigate the effects of dietary chitosan oligosaccharide (COS) supplementation on growth performance, antioxidant capacity, immune function, duodenal digestive enzyme activity,...