PLoS ONE
Articles in this Issue
Implementation and survey evaluation of a new safety concern escalation pathway among nursing team members
Introduction Escalating patient safety concerns is a critical component of healthcare delivery and can be impeded by organizational barriers including power hierarchies and fear of...
The effects of physical activity and platelet-high-density lipoprotein cholesterol ratio on the risk of anxiety disorders: A cross-sectional study based on NHANES 2015–2023
Anxiety disorders are a global mental health issue that is strongly associated with lifestyle factors. Physical activity (PA) could benefit anxiety symptoms, though the precise effect remains controve...
Acute and chronic effects of plyometric exercise performed with hypoxia on post-activation performance enhancement (PAPE)
In the literature, no study is available either to investigate the effects of conditioning activity (CA) applied in hypoxic conditions on post-activation performance enhancement (PAPE) or to examine w...
Integrative GWAS and RNA-Seq analysis for target identification and virtual drug screening in colorectal cancer
Background Colorectal cancer (CRC) is a leading cause of global cancer-related mortality, necessitating the identification of novel therapeutic targets. Integrating genetic and tra...
Cytomegalovirus reactivation in mechanically ventilated patients with or without SARS-CoV-2 infection: A retrospective cohort study
Background Data comparing the incidence, risk factors and outcomes of cytomegalovirus (CMV) reactivation in SARS-CoV-2 positive and negative patients remain controversial....
Zoonotic bacteria in invasive California Kingsnake Lampropeltis californiae from Gran Canaria, Canary Islands, Spain
Introduction Invasive species can spread pathogens to newly colonised areas and indirectly affect animals and humans. In the Canary Islands territory (Spain)...
Detection of PDR5-mediated alachlor efflux using a chemically induced dimer biosensor
The development of herbicide-resistant crops is a key strategy for achieving efficient and sustainable agriculture. Herbicide tolerance can be conferred by transporters that mediate the efflux of herb...
Nonlinear relationship between blood urea nitrogen to albumin ratio and mortality risk in older patients with cerebrovascular and cardiovascular diseases: An NHANES analysis
Background The blood urea nitrogen to albumin ratio (BAR) has emerged as a potential prognostic biomarker in elderly patients with cardiovascular and cerebrovascular diseases (CVDs...
Multimodal emotion recognition via adaptive high-order transforme network
Multimodal emotion recognition leverages multiple modalities to capture emotional cues more comprehensively, thereby improving the accuracy and robustness of emotion recognition. From the perspective...
Correction: Validation of the person-centered maternity care scale at governmental health facilities in Cambodia
Correction: Association between self-administrated prophylactics and SARS-CoV-2 infection among traditional market vendors from the Central Highlands of Peru: A nested case-control study
Novel insights into neuropathy: The impact of prolonged hyperglycemia on long non-coding RNA expression
Multiple evidence suggests that type 1 diabetes triggers perturbations in the nervous system both in human patients as well as in animal models of the disease. These perturbations are likely controlle...
Extended Directed Fuzzy Social Network Analysis: A framework and application to curriculum networks in Chinese vocational education
Due to the differences in node types and the diversity of network relationships, Fuzzy Social Network Analysis (FSNA) needs to specifically address the issues of network heterogeneity and relationship...
The impact of patent activity on idiosyncratic volatility in U.S. pharmaceutical companies
This study examines the impact of patent activity on the idiosyncratic volatility (IVOL) of U.S. pharmaceutical companies, addressing a critical gap in the literature on the relationship between innov...
Citation proximus: The role of social and semantic ties on citations
Despite being considered as key indicators of research impact, citations are shaped by factors beyond intrinsic research quality—such as including prestige, social networks, and research topics. While...
Dual-branch differential channel hypergraph convolutional network for human skeleton based action recognition
Graph Convolutional Networks (GCNs) perform well in skeleton action recognition tasks, but their pairwise node connections make it difficult to effectively model high-order dependencies between non-ad...
Sequencing and analysis of 131 SARS-CoV-2 isolates in previously sampled and unsampled regions of Jordan from 2020 to 2023
The Hashemite Kingdom of Jordan remains an understudied country for next generation sequencing analysis of SARS-CoV-2 genomes collected during the 2019 pandemic. Here we provide 131 additional referen...
Longing for touch and CT-optimal touch perception after interpersonal trauma
It has previously been shown that interpersonal trauma (IPT) can negatively impact the experience and perception of social touch. There are, however, also indications that people with IPT might simult...
Associations of temperature and precipitation with malaria in children under 5: A multi-country study in Sub-Saharan Africa
Climate change is a significant global challenge with major impacts on human health. It directly affects vector-borne diseases such as malaria by expanding vector ranges, boosting reproduction and bit...
Individual and community level factors of malaria among under-five children in Kenya: Based on the Kenya Demographic and Health Survey
Background Malaria remains a significant global public health challenge. In Kenya, it is a leading cause of illness and death among children under five in malaria-endemic areas. Un...
Exosomes combined with extra virgin olive oil reduces lipogenesis, oxidative stress, and inflammation in non-alcoholic fatty liver disease model
In response to high-fat-diet, excessive lipid accumulation in the liver results in chronic damage and inflammation. Olive oil has been studied for its health beneficial effects in hyperlipidemia (main...
MED-EL hearing solution registry: An examination of the strengths and limitations of a cochlear implant registry
There is a significant gap in routine clinical data concerning cochlear implant (CI) users, particularly regarding real-world outcomes. To address this, the present study focuses on the MED-EL Hearing...
Comprehensive analysis of cuproptosis-related genes in diabetic cardiomyopathy
Background Diabetic cardiomyopathy (DCM) represents a distinct myocardial pathology arising from chronic diabetic metabolic disturbances, characterized by progressive structural an...
Dialogic Social Impact Analysis of Companies and Organizations (DSIACO): A pioneer model for evaluating social impact of companies and organizations
Scientific literature has clarified that companies’ social impact is crucial in improving society by optimising their performance and relationship with their stakeholders, creating long-term value. Co...
Safety evaluation of cinacalcet: Signal mining and analysis of adverse events based on the FAERS database
Objective This study utilized the FDA Adverse Event Reporting System (FAERS) to assess signals of adverse events (AEs) associated with cinacalcet, aiming to enhance its safe and ra...