PLoS ONE
Articles in this Issue
Chaetomium, Chlonostachys, and Pseudogymnoascus isolates from tomato tissues significantly suppress Phytophthora infestans in tomato
Late blight is a disease whose causative agent is the oomycete Phytophthora infestans. It is one of the most destructive pathogenic oomycetes and a major challe...
An efficient cyber-attack detection and classification in IoT networks with high-dimensional feature set using Levenberg-Marquardt optimized feedforward neural network
This paper examines the escalating challenge of detecting cyber-attacks within Internet of Things (IoT) networks, where conventional security measures often falter in addressing the speed and complexi...
Screening mild cognitive impairment using aspects of personal, social, and functional lifestyle: Machine Learning Approaches
Objective Mild cognitive impairment (MCI) signals cognitive decline beyond normal aging and increases dementia risk. Early identification enables preventative interventions, yet ma...
Molecular consequences of mitochondrial replacement may be masked from organismal traits in Tigriopus californicus
Mitochondrial replacement therapy (MRT) presents a promising preventative measure to combat mitochondrial diseases. However, the long-term consequences of disrupting mitonuclear coevolution at both th...
Assessment approaches and methods in physiotherapy education: A scoping review protocol
Introduction Assessment in physiotherapy education is essential to ensuring graduates meet professional standards, demonstrate competence and are prepared to provide high-quality,...
Incidence and predictors of dehydration among preterm neonates admitted to the neonatal intensive care unit of Southern Ethiopia hospitals: A prospective follow-up study
Background Dehydration is one of the causes of preterm morbidity and mortality. Many efforts are being implemented to decrease the cause of preterm mortality, but there is a gap re...
Kinetic analysis suggests that malathion at low environmental exposures is not toxic to humans
Malathion has the reputation of being a safe pesticide. There are no reported cases of cholinergic toxicity in people exposed to low environmental doses of malathion. Our goal was to explain the safet...
Anti-inflammatory effect of bergamot leaves extract attenuates cardiac remodeling in obese rats by regulating the protein expression of the collagen/metalloproteinase axis
Inflammation is associated with the pathogenesis of obesity-related disorders, including cardiac remodeling. Bergamot is known for its promising anti-inflammatory effects. Thus, this study aimed to in...
Intraoperative cell-salvaged versus allogeneic red blood cell transfusions in high-bleeding-risk cardiovascular surgery: Protocol for a single-center, randomized, parallel-group, noninferiority trial
Introduction Patients who undergo cardiac surgery have a high risk of significant blood loss and anemia. While allogeneic red blood cell (RBC) transfusions are effective, they are...
Effectiveness of Antenatal Corticosteroids in reducing morbidities and mortality in Preterm neonates: Evidence from a Tertiary Level Hospital in Nepal
Background The use of antenatal corticosteroids (ACS) in mothers less than 34 weeks’ period of gestation has shown promising results with significant reduction in neonatal mortalit...
Sacubitril/valsartan preserves kidney function in rats with cardiorenal syndrome after myocardial infarction
Renal dysfunction in heart failure increases mortality, limits treatment options and blunts responses to therapy. Angiotensin receptor-blocker and neprilysin inhibitors (ARNI) may preserve renal funct...
Video-based pelvic floor muscle therapy for patients with pelvic floor disorders: A Protocol for a prospective single-arm pilot and feasibility study
The number of patients who suffer from pelvic floor disorders increases with age and can have a significant impact on quality of life. The first-line treatment for these different disorders includes p...
A novel variant in MYBPC3 causes hypertrophic cardiomyopathy by haploinsufficiency
Background Familial hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease (CVD). Related mutations contributing to hypercontractility and poor relaxat...
Epidemiological characteristics of hand, foot and mouth disease in Pingdu, Shandong, China from 2013 to 2023 and DLNM analysis of its variation with temperature
Background The purpose of this study is to describe the epidemiological situation of HFMD in Pingdu over the past decade, and investigate the relationship between environmental fac...
Structural optimization of pit bionic drip irrigation emitter to improve hydraulic performance and anti-clogging performance
The blockage inside the flow channel of drip irrigation emitters is a key issue that restricts their usability. The low-speed vortex zone that exists in traditional channel design is the core reason....
Impact of hydatid cyst laminated layer antigens on cell death rate, apoptosis induction, and key genes in the cell proliferation pathway: Insights from A549 cell line studies
While lung cancer remains a lethal disease despite treatment advances, some parasitic infections can demonstrate cancer-modulating roles and exhibit anti-tumor effects. The emergence of hydatid cysts...
Key body size/shape predictors of physical fitness in Saudi College-aged males: Role of the body roundness index
Physical fitness, a crucial factor in health and well-being, is influenced by an individual’s body composition. This study aimed to identify the key body size/shape predictors of fitness test performa...
TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS), characterized by myelin damage and neurodegeneration. This study focuses on the role of the TRIM37-PEX5 axi...
The validity and reliability of motion analysis sensor system for wheelchair users (MASSWU)
The Motion Analysis Sensor System for Wheelchair Users (MASSWU) is designed to collect wheelchair movement data such as distance, duration, speed, and angular velocity during competitions and training...
MultiFAR: Multidimensional information fusion with attention-driven representation learning for student performance prediction
The advancement in computing technology, online learning platforms, and pedagogical tools enable educators and learners to connect without temporal and geographical boundaries. The existing deep learn...
Predictive value of aorta enhancement on computed tomographic pulmonary angiography in pulmonary embolism
Background Pulmonary embolism (PE) is a life-threatening condition requiring prompt diagnosis and treatment. Visual assessment of computed tomographic pulmonary angiography (CTPA)...
Epistemically unwarranted beliefs scale, development and evidence of validity in the Chilean population
The study of epistemically unwarranted beliefs (EUB) (i.e., paranormal, pseudoscientific and conspiracy beliefs) has become relevant due to the negative effects they have produced on people’s health,...
Volumetric MRI of dorsal root ganglia as a biomarker for disease progression and response to AAV treatment in a mouse model of Fabry disease
Noninvasive and objective biomarkers for disease-associated pathology are critical for clinical trials. For Fabry disease, one important pathological change due to the deficiency of the lysosomal enzy...
RETRACTED: Unlocking employee creativity: How learning orientation and transformational leadership spark innovation through creative self-efficacy
This study explores the mechanisms through which individual learning orientation (ILO) and transformational leadership (TL) foster employee creativity, with a particular focus on the mediating role of...