PLoS ONE
Articles in this Issue
A mixed methods study protocol evaluating early screening, triaging, risk assessment and health optimisation in perioperative pathways
Background Over 10 million operations are carried out every year in the UK, improving millions of lives. While most operations are low-risk, some result in patients having poor out...
‘That’s just weird’: A qualitative investigation into expert opinions on the difference between autonomous vehicles and humans deciding to kill
Autonomous vehicles (AVs) are rapidly developing and in the process of being deployed on public roads. This has sparked extensive discussions on the ethics of AVs, particularly in collision scenarios....
Interpretable weakly-supervised learning through kernel density matrices: A digital pathology use case
Classification methods based on deep learning require selecting between fully-supervised or weakly-supervised approaches, each presenting limitations in uncertainty quantification and interpretability...
Family and personal factors predisposing adolescents to substance abuse in high-risk urban areas
Objective This study explored the influence of personal and familial factors on adolescent substance abuse in high-risk urban areas. The aim was to identify psychological and famil...
Can neoadjuvant chemoradiotherapy be omitted in cT2N+ and cT3 mid-rectal cancer: Protocol for a prospective, observational, cohort study (CANO)
Background Neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision (TME) is the standard treatment for locally advanced rectal cancer. However, nCRT is associate...
The trust–NPS correlation: The role of trust in promoting customer loyalty in Swiss financial institutions
The Net Promoter Score (NPS) is a widely used key performance indicator (KPI) for measuring customer loyalty and guiding customer-centric strategies. While customer trust has been identified as an imp...
Mature tau pathology is not improved by interfering with interleukin-1 receptor signaling in two mouse models of tauopathy
Prior work suggests that the cytokine interleukin-1β (IL-1β) may be a key regulator of tau pathology in the presence of amyloidosis. Here, we tested the possible benefits of interleukin-1 receptor ant...
An exploratory study of psychological and decision-making outcomes among family members of critically ill patients
Introduction Family members of critically ill patients are often required to make complex medical decisions under emotional distress, which may affect their decision-making capacit...
Unleashing recyclates for enhanced mechanical and durability performances of ternary blended concrete
The recycling of waste materials as environmentally friendly cement alternatives to lessen the impact of CO 2 emissions and safeguard natural resources associat...
Correction: Counterintuitive relationship between the triglyceride glucose index and diabetic foot in diabetes patients: A cross-sectional study
Adaptive multi-channel dehazing for enhanced visibility in underground coal mine images
Image dehazing has gained significant attention due to its importance in enhancing image clarity in various applications. However, existing algorithms often struggle with suboptimal performance in und...
Evaluation of the soil microbiome of three raised beaches in the Devon Island Lowland, High Arctic, Canada
The Arctic region is characterized by severe temperatures and a unique ecosystem with largely unexplored microbiomes. Whereas soil microbiomes in temperate regions play key roles in nutrient cycling,...
Stereotypy is strongly linked to multiple biomarkers of oxidative stress—A potential common etiology for Abnormal Repetitive Behaviors
Spontaneous stereotypies (abnormal, repetitive, and seemingly goal-less behaviors) in captive animals resemble stereotypies documented in patients with neurodevelopmental disorders, including evidence...
Alexithymia and attachment dimensions in relation to parental burnout: A structural equation modelling approach
Background Parental burnout is a chronic, parenting-specific syndrome marked by emotional exhaustion, emotional distancing from one’s children, and reduced parental fulfilment. Alt...
Brain volumetric reductions in patients with thrombotic thrombocytopenic purpura
Introduction Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder caused by a deficiency of a disintegrin and metalloproteinase with a thrombospondin type 1 mot...
DLLT: A dual-layer LSTM-transformer model for real-time energy and dynamics prediction in plug-in hybrid electric vehicles
Plug-in Hybrid Electric Vehicles (PHEVs) are increasingly favored for their low emissions and freedom from range anxiety, combining electric efficiency with the extended range of a gasoline engine. Wh...
Clinical characteristics, outcomes, and subtype diversity in hospitalized human rhinovirus (HRV) patients
Background Human rhinovirus (HRV) is a major cause of respiratory illness, however data on clinical presentation, outcomes across age-groups and associations with HRV subtypes are...
Limits of life: Thermal tolerance of deep-sea hydrothermal vent copepods and implications for community succession
Organisms that live in extreme marine environments naturally experience intermittent exposures to the limits of their physiological potential at different time scales and have developed diverse strate...
Adapting the WHO Behavioural and Social Drivers of Vaccination (BeSD) tools and Vaccination Attitudes Examination (VAX) scale for pregnant women in South Africa: Insights from a mixed-methods pilot study
Background Understanding vaccine attitudes, knowledge, and perceptions is critical for improving vaccine uptake, particularly among vulnerable populations such as pregnant women. T...
Investigation on the influence of unbalanced shaft component in gearbox on displacement using the Newmark-β method
This study introduces an enhanced numerical approach for analyzing the dynamic behavior of a rotor-bearing system subjected to unbalanced excitation from a gearbox drive shaft. The Newmark-β method wi...
Environmental heterogeneity plays a bigger role than diet quality in driving divergent California sea lion population trends
While the global population of California sea lions ( Zalophus californianus ) is increasing, regional trends show a...
Relationship between HLA-DRB1 shared epitope alleles and peripheral blood monocyte counts in Japanese patients with rheumatoid arthritis
Objectives To investigate the relationship between Human Leukocyte Antigen-DR beta 1 (HLA-DRB1) shared epitope (SE) alleles and peripheral blood monocyte counts in disease-modifyin...
Retraction: Unleashing the role of e-word of mouth on purchase intention in select Facebook fan pages of smart phone users
Comparative evaluation of score criteria for dynamic Bayesian Network structure learning
Dynamic Bayesian Networks (DBNs) are probabilistic models with a directional structure employed to model temporal processes. Three approaches to DBN structure learning are constraint-based, score-base...