PLoS ONE
Articles in this Issue
Effects of long working hours on metabolic dysfunction-associated steatotic liver disease, with and without increased alcohol intake, in healthy workers: A 10-year cohort study
Long working hours are increasingly recognized as a significant occupational hazard linked to various adverse health outcomes. This study aimed to assess how prolonged working hours relate to the subs...
Thermal environment simulation and analysis of renovated solar greenhouses with enhanced cultivation area and space
In response to the issues of low land utilization efficiency and poor nighttime thermal performance in old single-slope solar greenhouses (SSG) commonly found in northern China, this study proposes re...
Correction: Development of a consensus-based core outcome set for post-treatment recovery in adults with epilepsy and comorbid depression or anxiety: A Delphi and ICF-guided protocol
Isotopic evidence of increased societal diversification in Pre-Columbian Panama
The Pre-Columbian history of Panama stands in unique contrast to the state-level societies of Mesoamerica to the north and the Andes to the south. Characterized by a network of powerful chiefdoms at t...
Assessment of industrial cheese ripening using near infrared spectroscopy technique: A scoping review protocol
Introduction Cheese maturation is an essential stage in dairy production, significantly influencing the sensory quality and market value of the final product. Traditional monitorin...
A compact ultra-wideband bandstop filter using mu-negative and ENZ metamaterial resonators for multiple advanced wireless communication systems
A compact ultra-wideband bandstop filter (UWB-BSF) based on a microstrip line and innovative complementary electrical LC (CELC)-loaded metamaterial (MTM) resonators is proposed. These MTM resonators e...
Hepatic arterial infusion is effective in patients with unresectable colorectal liver metastases refractory to standard systemic chemotherapy: A retrospective cohort study
We identified an effective chemotherapy regimen in patients refractory to standard chemotherapy. We included patients with unresectable colorectal liver metastases who underwent hepatic artery infusio...
Sex-stratified pharmacovigilance of gastrointestinal events associated with first-line smoking-cessation medicines: Insights from the FAERS database
Background Tobacco smoking is a major global health threat. Pharmacological aids, including nicotine-replacement therapy (NRT), varenicline, and bupropion, improve quit rates but a...
Parenting beliefs and psychological distress → stimulation and punishment → young children’s behavior: A descriptive study in Colombia
Parental engagement in stimulating activities and the use of different discipline behaviors play a significant role in young children’s behavioral development. Psychological frameworks often posit tha...
Mortality risk prediction in NSTE-ACS following PCI: Insights from a real-world cohort
Background Non–ST-segment elevation acute coronary syndrome (NSTE-ACS) is a major contributor to cardiovascular mortality, yet reliable tools for individualized mortality predictio...
Semi-supervised synthesis of 7T MRI from 3T using 3D FR-U-Net with anatomical segmentation consistency assessment
Ultra-high-field 7T MRI provides substantial benefits for neuroimaging, including improved resolution and contrast, but remains limited by high costs and restricted accessibility. In this study, we pr...
Requiem of Olympic ethics and sports’ independence: A panel-data socio-cultural analysis
This paper suggests a theoretical model (a production function) and an empirical model (Stochastic Frontier Analysis) to empirically evaluate the main impacts o...
Design of a multi-epitope recombinant BCG vaccine targeting Brucella OMP31, LptE and VirB2 in immunoinformatics approaches
Brucellosis, caused by the intracellular pathogen Brucella , remains a significant health challenge, alongside subst...
Genome-wide identification and expression analysis of Phenylalanine Ammonia-Lyase (PAL) in cucumber
Phenylalanine ammonia-lyase (PAL) is the key catalytic enzyme that initiates the phenylpropanoid metabolic pathway. This study identified 13 members of the cucumber PAL...
The effect of environmental stressors on anti-mullerian hormone levels in Lebanese women: a retrospective study
Background Prolonged and repetitive exposure to stressors leads to detrimental effects on female reproductive health; this can consequently increase susceptibility to stress and el...
Impact of blood culture positivity at intensive care unit admission on mortality in infective endocarditis: Machine learning and deep learning-based causal inference models
Background Infective endocarditis (IE) carries high in-hospital mortality, particularly among intensive care unit (ICU) patients. The predictive role of blood culture positivity in...
Development of genomic markers for monitoring and research on plethodontid salamanders
Despite the importance of plethodontid salamanders and their vulnerability to ongoing environmental change, they are inherently difficult to monitor due to their cryptic nature. Recent advances in gen...
Xiao Qing Long Tang ameliorates neutrophil extracellular trap-dendritic cells-T helper 17 cell axis in Neutrophilic Asthma
Background Neutrophilic asthma (NA) is an allergic airway inflammation disease featuring heterogeneous neutrophil infiltration, which is driven by the interactions between dendriti...
Impact of rich cultural tourism experience on tourist satisfactions and behavioral intentions toward Ningxia’s cultural heritage: Moderation role of perceived cultural distance
Ningxia is a renowned cultural tourism destination with rich heritage and natural landscapes. Current research, however, remains unclear on how multi-dimensional cultural experiences influence tourist...
Cross-cultural adaptation and psychometric validation of the STarT back tool for Jordanian Arabic-speaking adults with low back pain
Background The Keele STarT Back Tool (STarTBack) was developed to categorize people with low back pain based on disability risk. The tool was cross-culturally adapted and validated...
Exploring levels and factors associated with transition challenges for Syrian refugee parents resettled in Canada
Although the literature has documented numerous challenges Syrian refugees face during their resettlement in Canada, the unique transition experiences of Syrian refugee parents remain underexplored. T...
Simulating macroevolutionary trends and open-ended evolution with a novel mechanistic multi-level approach
Microevolution and macroevolution describe evolutionary change at different scales: short-term genetic and phenotypic variation within populations, and long-term patterns of diversification and extinc...
Molecular phylogeny of the diatom genus Planothidium with the description of Paraplanothidium gen. nov. and Pseudoplanothidium gen. nov.
One of the characteristic features of the monoraphid genus Planothidium is the structure of the central part of the rapheless valve. Planoth...
Social associations and habitat selection delineate two subpopulations of west coast transient killer whales (Orcinus orca rectipinnus) in the California Current System
West coast transient (mammal-eating) killer whales ( Orcinus orca rectipinnus ) inhabit the California Current off the west coast of North America from southern...
Improving the safety of outpatient to Emergency Department transfers: A quality improvement study in a tertiary hospital in Pakistan
Background Safe and coordinated patient transfers are essential for reducing morbidity, mortality, and adverse events. In outpatient clinics, early recognition of patient deteriora...