PLoS ONE
Articles in this Issue
Comparison of outcomes between minimally invasive percutaneous bunnell suture and traditional open modified Kessler technique for acute closed achilles tendon rupture: A single-center cohort study
Percutaneous Bunnell repair and open modified Kessler repair remain debated options for acute Achilles tendon rupture (AATR). We retrospectively compared a minimally invasive percutaneous Bunnell tech...
Correction: Targeted modulation of MMP9 and GRP78 via molecular interaction and in silico profiling of Curcuma caesia rhizome metabolites: A computational drug discovery approach for cancer therapy
A disproportionality analysis of FDA adverse event reporting system (FAERS) events for filgotinib
Background Although filgotinib, a selective Janus kinase 1 inhibitor, has been increasingly applied in the treatment of inflammatory diseases, its comprehensive safety profile rema...
A large-scale trial in Chennai, India shows effective reduction of Anopheles stephensi populations by the biolarvicide Natular
Biolarvicides present an environmentally safer alternative to chemical larvicides, demonstrating selectivity against target species. However, the available options for biolarvicide use in mosquito con...
Gender and mental health of adolescents: A conceptual framework developed in a Delphi study
Objective Adolescence is one of the most neglected developmental phases, yet there are few phases in the life course when gender socialisation is as intense. So far, no framework o...
Validation of the Rosenberg Self-Esteem Scale among the Iranian adult population: A cross-sectional study
Background Self-esteem refers to an individual’s overall sense of self-worth, which plays a crucial role in their well-being. One of the most commonly used instruments to measure t...
Lexical feature analysis of Chinese informed consent forms based on the information entropy methods: A paired study of minor and their guardian’ version
High-quality informed consent forms (ICFs) are crucial to facilitate effective communication between researchers and patients. However, the complex and specialized terminologies in ICFs often result i...
Editorial Note: Measurement and driving factors of carbon productivity in China’s provinces: From the perspective of embodied carbon emissions
Zinc ion increases the effectiveness of phosphorus in agricultural soils through microbial solubilization
Phosphorus (P) is a key limiting factor for crop growth in agroecosystems, where soil microorganisms and mineral ions are essential for P turnover and mobilization. However, it is unclear how mineral...
Hybrid machine learning models for enhanced arrhythmia detection from ECG signals using autoencoder and convolution features
Automated arrhythmia detection from electrocardiogram (ECG) signals is crucial and important for the early treatment of cardiac disease (CD). In this investigation, eight machine-learning models have...
Decentralized trust optimization in VANETs: A blockchain-driven hybrid PoS-PBFT architecture for enhanced security and energy-efficient communication
Vehicular Ad Hoc Networks (VANETs) are essential for the success of Intelligent Transportation Systems (ITS), providing real-time communication between vehicles and infrastructure. However, the highly...
Reduction of noise pollution in CNC wood milling through multi-parameter optimization using response surface methodology
Background CNC (Computer Numerical Control) wood milling machines offer significant productivity advantages but are associated with excessive noise pollution, posing health risks t...
Association between fusion and clinical outcomes after anterior cervical discectomy at 1-, 2- and 5-year follow-up
Introduction Fusion achievement is considered a crucial factor in recovery following anterior discectomy. Nevertheless, the direct correlation between fusion and clinical outcomes,...
PRCnet: An efficient model for automatic detection of brain tumor in MRI images
Brain tumors are the most prevalent and life-threatening cancer; an early and accurate diagnosis of brain tumors increases the chances of patient survival and treatment planning. However, manual tumor...
A mixed-methods study to explore the modifiable aspects of treatment burden in Parkinson’s disease and develop recommendations for improvement
Background People with Parkinson’s (PwP) and their caregivers have to manage multiple daily healthcare tasks (treatment burden). This can be challenging and may lead to poor health...
Correction: Associations between age at natural menopause and risk of hypothyroidism among postmenopausal women from the Canadian Longitudinal Study on Aging (CLSA)
Health risk realization versus warning: Impact on lifestyle behaviours
Using individual-level panel data from Understanding Society I estimate the response to a health risk realization on a healthy lifestyle index. To overcome the...
High-protein diets reduce plasma pro-inflammatory cytokines following lipopolysaccharide challenge in Swiss Albino mice
Macronutrients serve as principal sources of energy, structural components, and regulators of physiological processes. However, the optimal macronutrient combination for health remains unclear. While...
A fast regulation algorithm for low voltage in regional grids with high uncertainty and high penetration of wind and solar loads at the grid end
To address the issue of low voltage fluctuations at the grid end caused by the high penetration of wind and solar loads in the power grid, a fast low-voltage regulation algorithm is proposed. This alg...
Enhancing drug repositioning: A multi-class ensemble model for drug-target interaction prediction with action type categorization
Accurate prediction of drug–target interactions (DTIs) is critical for accelerating drug repositioning and reducing the cost of pharmaceutical development. Most existing studies frame DTI prediction a...
“You just forget about preeclampsia and move on” –awareness of chronic disease risks and follow-up preferences after preeclampsia in Ireland: a national qualitative study
Background Preeclampsia is associated with increased long-term risks of cardiovascular disease, kidney disease, and stroke. International guidelines recommend structured follow-up...
Correction: The impacts of product characteristics and regulatory environment on smokers’ preferences for tobacco and alcohol: Evidence from a volumetric choice experiment
Investigating risk factors of hemorrhagic fever of renal syndrome (HFRS) in Qingdao, Shandong province, China
Background Qingdao, a historically high-risk area for hemorrhagic fever with renal syndrome (HFRS) in China, is undergoing agricultural mechanization and urbanization. However, the...
Factors influencing physical activity for hypertension prevention among older adults in a peri-urban community in Ho, Ghana
Background Regular physical activity is proven to be an effective risk-reduction strategy against hypertension among older adults. This study assessed the factors influencing regul...
Mycobacterium tuberculosis complex lineages and drug resistance patterns among tuberculosis patients with or without diabetes mellitus in southern Ghana
Drug-resistant (DR) tuberculosis (TB) and diabetes mellitus (DM) are intersecting epidemics that complicate management of both diseases and worsen patient outcomes. We conducted a prospective cohort s...