PLoS ONE
Articles in this Issue
Classification of virulence factors based on dual-channel neural networks with pre-trained language models
Virulence factors (VFs) are crucial molecules that enable pathogens to cause infection and disease in a host. They allow pathogens to evade the host’s immune defenses and facilitate the progression of...
Retraction: Downregulation of FBP1 Promotes Tumor Metastasis and Indicates Poor Prognosis in Gastric Cancer via Regulating Epithelial-Mesenchymal Transition
Correction: Is it enough to utilize a single anchor for repair of rotator cuff tears ≤ 3 * 3 cm²?
“… I tried to commit suicide…”: Understanding the intersections between mental health, HIV and teenage pregnancy
Background Adolescent girls in South Africa face a range of interconnected health challenges, including high rates of unplanned pregnancy and HIV infection, which are compounded by...
Evaluation of a home pharmaceutical care service model for home-based patients receiving anticoagulation therapy within county-level medical community
Objective To establish a systematic, standardized, and operational model of home pharmaceutical care for patients with anticoagulant treatment in county-level medical community....
Near obstacles detection by inverse perspective mapping of AVM for intelligent vehicles
Although state-of-the-art sensors, such as LiDAR, radar, monocular camera, along with detection algorithms for intelligent vehicles, generally exhibit superior performance in object detection and reco...
Spatial-temporal evolution and influencing factors of sudden environmental accidents in China from 2008 to 2022
The spatiotemporal evolution characteristics and influencing factors of sudden environmental accidents are analyzed by employing exploratory spatial analysis and Pearson correlation analysis, based on...
FedGraphHE: A privacy-preserving federated graph neural network framework with dynamic homomorphic encryption and robust aggregation
Federated learning (FL) enables collaborative model training across distributed intelligent devices while preserving data privacy. In smart healthcare networks, medical institutions can jointly learn...
Effects of Square-Stepping Exercise on cognitive function in early geriatric rehabilitation: A randomized controlled explorative study
Objectives The aim of the explorative study was to evaluate the effect of Square-Stepping Exercise (SSE) on cognitive function compared to conventional physiotherapy (cPT) in early...
Molecular insights into heart field-specific cardiomyocyte differentiation - A computational study
Understanding the mechanisms underlying cardiomyocyte (CM) differentiation is essential for the accurate generation of the different types of heart cells in vitro. This study advances current models o...
Impingement of deposited water nanodroplets with coming nanoparticles: A molecular dynamics study
Nowadays, the manipulation of water droplets has received growing interest in both academia and industry. In the current work, we aim to induce a quick sweep of deposited water droplets upon surfaces...
Validation of the Malay Version of the Caregiver Quality of Life Index–Cancer (MCQoL) among caregivers of cancer patients in Malaysia
Cancer caregivers frequently experience significant psychological distress as they manage the increasing treatment burden of cancer patients, which adversely impacts their quality of life. In Malaysia...
Research on the development trend of global running protection equipment technology from the perspective of patent measurement
This study provides a systematic examination of global development trajectories in running protective equipment by applying large-scale patent mining and quantitative analysis to international and dom...
Economic evaluation of biomarker-based surveillance for Hepatocellular Carcinoma in Thai patients with Compensated Liver Cirrhosis
Objective Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death in Thailand. However, most Thai patients at high risk of HCC lack access to routine surveillan...
Impact of high sodium intake on stomach cancer burden in China: A comprehensive analysis from 1990 to 2021
Background Stomach cancer remains a significant public health concern in China, with dietary factors, particularly high sodium intake, being major contributors. This study aimed to...
Applying nanoemulsions produced from the essential oil mixture of citronella and Coleus Amboinicus to preserve minced chicken meat
This study investigated the preservative potential of four essential oils (EOs): citronella (Ci), Litsea cubeba (Lc), Coleus amboinicus...
Parkinson’s disease gait rehabilitation at scale: Insights on personalised smartphone-based music cueing
This study investigates the perceptions of people with Parkinson’s Disease (PwPD) regarding the use of a smartphone-based music cueing application (app). We present CuePD...
Improved birth rates via rehydration of mouse freeze-dried spermatozoa using high-temperature ultrapure water
Freeze-drying (FD) is a promising method for achieving the long-term, low-cost, and safe preservation of mammalian sperm at room temperature (RT, 23–25°C). However, the birth rate of embryos fertilize...
Estimating the economic burden of COVID-19 survivors in Punjab, Pakistan
Background The COVID-19 survivors are under a great deal of financial stress due to high medical costs, income lost during illness, and ongoing medical expenses. Many survivors bor...
Toward a safer school environment: A mixed-methods analysis of bullying and its impact on romanian middle school students
Our study investigated the complex and nuanced phenomenon of bullying in the Romanian educational context, using a mixed methods approach. Its objective was to analyze the implications and effects of...
Genetic diversity, genetic population structure and epidemiology of multidrug resistance Neisseria gonorrhoeae from Kenya
Neisseria gonorrhoeae is the bacterial agent responsible for gonorrhea, a common sexually transmitted infection. The emergence of Neisseria gonorrhoeae...
A comprehensive risk assessment method for Christmas tree combined with a multi source information fusion algorithm and an improved HAZOP method
The Christmas tree faces significant safety risks during installation and requires extremely high reliability during operation. In this study, a comprehensive risk assessment method combined GA-BP neu...
Soil microbiome perturbation impedes growth of Bouteloua curtipendula and increases relative abundance of soil microbial pathogens
Bouteloua curtipendula (sideoats grama) is a valuable prairie grass for livestock forage, supporting food webs of herbivorous insects, reducing soil erosion, and limiting weed infi...
Experimental investigation of the influence of friction, surface roughness and material hardness on the external load factor in threaded joints
Threaded joints, particularly bolted joints, are critical components in the design and fabrication of mechanical systems due to their high strength and ease of disassembly. Their widespread applicatio...