PLoS ONE
Articles in this Issue
Identification of ACE and HSPB8 as novel drug targets for LUSC treatment and prognosis based on a prognostic model integrating epigenetic regulation and endoplasmic reticulum stress-related genes
Background Lung Squamous Cell Carcinoma (LUSC) remains a significant challenge in oncology due to limited diagnostic and therapeutic options. Epigenetic regulation and endoplasmic...
Functional equation modeling of adaptive operant-control systems via Matkowski fixed point theory
This paper presents a generalized form of the functional equation used in operant-control models by removing the requirement for initial conditions. The proposed formulation extends earlier studies in...
Feasibility of glycated haemoglobin target-setting in adults with diabetes: A mixed-methods study
Background HbA 1c targets guide diabetes management to reduce complications, yet their psychological effects are...
Similarity-aware VAE with wavelet-convolutional 1D-CNN for rolling bearing fault diagnosis
To address the uneven distribution of fault categories in data sets for deep learning-based fault diagnosis, we propose a fault diagnosis framework combining an improved Variational Autoencoder (Simil...
One health approach to Balantioides coli: Molecular and metabarcoding evidence of zoonotic transmission
Balantioides coli is a neglected zoonotic protozoan, with pigs recognized as its main reservoirs. In tropical countries such as Brazil, information on balantidiasis in occupational...
Electric field-induced rupture kinetics of giant unilamellar vesicles with varying gramicidin A content in membrane
In this study, we examine the rupture kinetics of giant unilamellar vesicles (GUVs) composed of DOPG/DOPC and varying mole fractions of gramicidin A (GrA), under externally applied electric fields. Ti...
Mapping Robusta coffee (Coffea canephora) cropping systems in Uganda: A two-step pixel and sub-pixel based approach with Sentinel-2 data
Coffee is a highly valued commodity and a widely consumed beverage, playing an important role in global trade. However, coffee farming landscapes are increasing transitioning into smaller-scale agricu...
Impact of population pressure on forest resources depletion in Yayo coffee forest Biosphere Reserve, Southwest Ethiopia
An increase in population density amplifies the demand for forest products, which in turn drives deforestation and the exhaustion of forest resource. The aim of the study was to assess the impact of p...
Effect of aromatherapy with Matricaria chamomilla in pain and anxiety management in hospital settings: A scoping review protocol
Introduction Pain and anxiety are underestimated complications in hospitalized patients, negatively impacting their well-being and physiological functioning. Integrative and Comple...
Correction: Exploring the relationship between motor visual proficiency and performance metrics in elite skeet shooters: An in-depth analysis
A fusion sparse learning algorithm for fault identification of rolling bearings
A key part of CNC machine tools is the rolling bearing, and thus, it is vital to employ a data-driven approach for fault diagnosis. This paper proposes a two-stage fusion sparse learning algorithm for...
Correction: Depression as a risk factor for Alzheimer’s disease: A human post-mortem study
Correction: What emotions are elicited by smells in Japanese people? Emotional measurement using a universal scale in Japanese
Autonomic nervous system maturation in preterm neonates: Correlation with gestational and postmenstrual age (ProMote)
Background Autonomic nervous system (ANS) maturation is crucial for neonatal adaptation, but in preterm infants, this process is often delayed, leading to increased vulnerability....
Integrating simulated and experimental data to identify mitochondrial bioenergetic defects in Parkinson’s Disease models
Mitochondrial bioenergetics are vital for ATP production and are associated with several diseases, including Parkinson’s Disease (PD). Here, we simulated a computational model of mitochondrial ATP pro...
The effect of diaphragmatic breathing and diaphragmatic mobilization on physical performance, fear of falling, and quality of life in community-dwelling older adults: A randomized controlled trial
Background Falls are a significant health concern among older adults, leading to reduced mobility, fear of falling, and poor quality of life. Diaphragmatic breathing (DB) and diaph...
Correction: Perceptions and practices of community pharmacists towards the use of short-acting beta-2 agonists inhalers in Malaysia: A cross-sectional survey
Correction: Antihypertensive therapy to prevent cardiac death: A study of combined ACE inhibitors and β-blockers—a retrospective cohort study in Tsunan Town, Japan
Evaluating the role of graft angle on cerebral hemodynamics following direct cerebral bypass for moyamoya disease
Direct cerebral bypass is a key treatment for moyamoya disease (MMD). This surgery grafts a donor vessel onto a recipient cerebral artery to boost blood flow to hypoperfused brain regions. Unlike coro...
Impacts of key environmental variables on suitable cultivation and flavonoid accumulation in Pueraria montana var. lobata under climate change in China
Pueraria montana var. lobata ( P. lobata ) is both a medicinal herb with significant pharmacological...
Dissecting the differential performance of contrasting stay-green and stem reserve mobilization wheat (Triticum aestivum L.) genotypes – Validation of GWAS analysis
The present study aimed to validate the identified marker trait associations (MTAs) for stay-green (SG) and stem reserve mobilisation (SRM) using 12 wheat genotypes. Out of 12 genotypes, equal number...
Barriers and facilitators to developing faith-based peer interventions in Islamic religious settings for obesity prevention in women: A qualitative exploratory study
Background Muslims represent the second-largest religious group in England and are geographically concentrated in socioeconomically deprived areas, predisposing them to health disp...
Correction: Adverse events of androgen receptor pathway inhibitors in prostate cancer from real world data
Editorial Note: Risk of stillbirth in singleton fetuses with advancing gestational age at term: A 10-year experience of late third trimester prenatal screenings of 50,000 deliveries in a referral center in northern Italy
Elevated mortality and upregulated SARS-CoV-2-associated pathways in innate and adaptive immune cells from individuals with Down syndrome
Trisomy 21 increases the risk of severe outcomes and mortality in hospitalized individuals with Down syndrome (DS) following SARS-CoV-2 infection. Using data from the Brazilian Epidemiological Surveil...