PLoS ONE
Articles in this Issue
The stigma of alcohol use during pregnancy: Exploring the impact of alcohol strength and social context on public perceptions
Alcohol use during pregnancy remains a major public health concern, with societal expectations of abstinence often resulting in stigma toward women who drink. To examine stigma and discrimination attr...
Does surgical approach affect Hirschsprung-associated enterocolitis risk? A comparison between transanal Swenson-like and endorectal pull-throughs
Hirschsprung-associated enterocolitis (HAEC) is a complication of Hirschsprung disease (HSCR) that may occur both before or after surgery. Transanal endorectal pull-through (TEPT) is one of the standa...
Short-term refractive and corneal astigmatism after canal-based microinvasive glaucoma surgery
Purpose To investigate changes in refractive and corneal astigmatism after Hydrus Microstent (Alcon Inc., Geneva, Switzerland) implantation during microinvasive glaucoma surgery....
Suicide adverse events associated with zopiclone and eszopiclone: A pharmacovigilance analysis based on FAERS, JADER and CVARD
Background Suicide adverse events are a serious concern with zopiclone and eszopiclone. This study assessed the risk of such events by mining data from the FAERS, JADER, and CVARD...
Merge-YOLO: An accurate detection model for book packaging defects in intelligent logistics scenarios
Driven by the knowledge economy and digitalization, the scale of book logistics continues to expand. However, the quality inspection process in this field currently uses generic target detection model...
Social determinants in the delay of starting colorectal cancer treatment
Delayed access to colorectal cancer (CRC) treatment leads to disease progression, advanced stages at diagnosis, and reduced survival. In Brazil, Law 12.732/2012 mandates treatment initiation within 60...
Evaluation of conditional treatment effect of salt stress on tomato sugar content using causal machine learning: A pilot study
Exposing tomatoes to salt stress has been reported to increase the fruit sugar content (°Brix); however, the causal impact of this treatment under varying environmental conditions remains unclear. In...
Hypoxemia prediction in pediatric patients under general anesthesia using machine learning: A retrospective observational study and external validation
Background Pediatric patients under general anesthesia are particularly vulnerable to hypoxemia, which can lead to rapid oxygen desaturation. This vulnerabil...
Prediction of differentiation levels in lung adenocarcinoma using peripheral blood inflammatory cytokines and tumor markers
Objective Lung Adenocarcinoma (LUAD) has highly aggressive and lethal, and its degree of differentiation significantly influences prognosis and treatment strategies, yet accurate p...
Translocated populations are genetically similar to natural populations and populations resulting from natural colonizations
Genetic diversity and structure are rarely assessed in populations established through conservation translocation. Here, we analysed the genetic structure and diversity of populations of an endangered...
A corpus-based analysis on the use of MAKE in sinologist Cyril Birch’s English version of Mistress and Maid (Jiaohongji)
While corpus-based translation studies have extensively analyzed lexical patterns, they exhibit critical theoretical limitations in integrating translation theories with empirical analysis, particular...
Script or style? Analysis of the relationship between teaching scripts and supervision style
Purpose Clinical teachers use both clinical and teaching scripts when supervising students. The aims of the study was: 1) to explore how teaching scripts are operationalized during...
Stability of salivary microRNA measures across an NCAA Division I football season: Implications for microRNA as a biomarker of concussion
Background Clinicians often face challenges in concussion care due to a heavy reliance on subjective patient input. Recently, research has sought objective biomarkers, like salivar...
Fine mapping and transcriptomics reveal OSG function in regulation of grain size and pollen fertility in rice (Oryza sativa)
Grain shape is a critical factor that directly influences rice yield and quality, however, the molecular mechanisms underlying the regulation of grain shape development remains elusive. In this study,...
Relationship between the Rate of Perceived Stability, electrodermal activity and task performance during balance challenges in chronic stroke
Introduction In addition to sensorimotor impairments following stroke, decreased self-efficacy regarding walking balance may lead to self-imposed limitations on community level mob...
Space-time clustering and temporal trend analysis of pulmonary tuberculosis in Brazil, 2010–2023
Background Identifying high-risk areas for pulmonary tuberculosis (PTB) is essential for understanding the dynamics of disease transmission and for guiding more effective control s...
Mechanical behavior of Port Basin Bulkheads Reinforced with novel multi-anchored sheet piles
To address the critical limitations of conventional parallel double-anchor support systems, including coplanar load imbalance, critical spacing risks, deviations from theoretical designs, and maintena...
How exercise adherence affects emotion regulation in Chinese college students: The chain mediating effect of sleep quality and self-efficacy
Objective This study investigated the mechanism through which exercise adherence enhances emotional regulation ability in college students, focusing on the chain mediating pathway...
Retraction: Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway
Multi-objective QSAR prediction of ERα antagonists via SHAP-based interpretation
To achieve a comprehensive evaluation of candidate drugs in terms of both biological activity and ADMET properties, this study proposes a two-stage predictive framework based on Quantitative Structure...
A simplified model for predicting the minimum miscibility pressure of CO2 flooding in reservoirs of the Ordos Basin
Minimum miscibility pressure (MMP) is a critical parameter in reservoir screening and development design for CO 2 flooding projects. With the expanding implemen...
Speak or shout? Nonverbal vocalizations promote rapid detection of emotions in vocal communication
Human vocal expressions of emotion can be expressed nonverbally, through vocalizations such as shouts or laughter, or speakers can embed emotional meanings in language by modifying their tone of voice...
Pharmacokinetics and analgesic efficacy of fentanyl and buprenorphine in chicken embryos
Chicken embryos are able to process and receive noxious stimuli from embryonic day (ED) 13. In the context of animal welfare, analgesic refinement is highly recommended for painful procedures from thi...
High microbial diversity in glacial habitats uncoupled from the specialized microbiomes of resident chironomid fauna
Ecosystems associated with retreating glaciers are undergoing rapid transformation in the context of a changing climate. Invertebrate fauna, including the Chironomidae insect family (non-biting midges...
Actigraphy-based sleep outcomes in substance use disorders: A protocol for a systematic review and meta-analysis
Introduction Individuals with substance use disorders (SUDs) are at increased risk for sleep disturbances, creating a bidirectional relationship that may heighten relapse risk. Whi...