PLoS ONE
Articles in this Issue
Current practice in prescribing footwear and insoles to reduce the risk of neuropathic plantar forefoot ulceration and re-ulceration in people with diabetes
Background Footwear and insoles are frequently used to offload the neuropathic diabetic foot at risk of ulceration and re-ulceration. This study aims to explore the prescription ha...
The multi-faceted effects of technology-driven productivity surge in the crop & livestock sector in Greece: Evidence from the FABLE Calculator
This paper the effects of a technology-driven increase in crop and livestock productivity on key agricultural, land-use, and environmental indicators in Greece, using the FABLE (Food, Agriculture, Bio...
Pulmonary fibroblasts activated by the addition of TNF-α and IL-4 enhance lymphangiogenic capacity and ameliorate lung fibrosis in an allogeneic rat model
Background Pulmonary fibrosis remains a major clinical challenge with limited treatment options. Recent studies have suggested that fibroblasts, when stimulated by specific cytokin...
Morphological characterization of Calotropis procera (Aiton) W.T. Aiton, a neglected medicinal plant
Calotropis procera (Aiton) W.T. Aiton, a medicinally significant but understudied species, exhibits remarkable adaptability to arid environments. Despite its ecological and pharmac...
Computational elucidation of stomidazolone mediated inhibition of stomatal differentiation and its implication in plant developmental regulation
Stomata play a critical role in plant physiology by balancing gas exchange and water conservation. Their development is driven by a precisely orchestrated sequence of cell divisions and differentiatio...
Investigations of a new EPS-insulated mortar-free reusable interlocking block for sustainable buildings
Sustainable, energy-efficient, and reusable construction systems have increasingly been demanded due to the increasing amount of plastics, waste, demolition debris, and the carbon footprints associate...
Correction: Co-generation of NaREE(MoO4)2 and REEPO4 in multiple habits by solid-flux crystal growth
Smallpox outbreak scenarios and reactive intervention protocols: A mathematical model-based analysis applied to the Republic of Korea
Smallpox, caused by the variola virus, remains a potential biosecurity threat despite its eradication. This study develops a mathematical model to evaluate outbreak scenarios and the effectiveness of...
The potential impact of wheat stem rust on global agricultural supply, demand, and food security, considering market interactions
Wheat stem rust, a fungal disease that can be highly devastating under the right environmental conditions, was reduced to non-economically damaging levels during the Green Revolution. However, it has...
Correction: Investigating the causal effects of COVID-19 vaccination on the adoption of protective behaviors in Japan: Insights from a fuzzy regression discontinuity design
Soil organic carbon dynamics: Influences of land-use change in natural and plantation forests of the Western Ghats, India
Soil organic carbon (SOC) is a fundamental component of the global carbon cycle, underpinning ecosystem health, climate regulation, and sustainable land management worldwide. The conversion of natural...
Refining weak supervision for robust lung cavity segmentation: A graph-affinity method with boundary constraints
Pixel-level annotation of lung cavities (LCs) in computed tomography (CT) images is challenging due to their morphological diversity and complexity. Weakly supervised semantic segmentation (WSSS) meth...
Evaluating the effectiveness of preservice midwifery curricula in Ethiopia: A comparison of neonatal resuscitation and infection prevention practice of midwifery graduates trained in competency-based versus conventional curricula
Background Infection control and neonatal resuscitation are essential midwifery practices that can reduce maternal and neonatal mortality. However, in Ethiopia, theory-heavy midwif...
AI-based prediction of recurrence after carbon ion radiotherapy for early stage non-small cell lung cancer
Lung cancer is a leading cause of cancer-related deaths. Carbon ion radiotherapy (CIRT) is a treatment modality for patients with inoperable conditions or who decline surgery, but there is room for re...
Beyond traditional stimuli: Validating AI-generated images for eliciting negative emotions in affect research
Studies of emotion often rely on standardized stimulus sets to elicit affective responses. Although established databases provide images with normative valence and arousal ratings, selecting suitable...
Editorial Note: A Meta-Analysis of Studies of Treatments for Feline Urine Spraying
Serological evidence of West Nile virus circulation in Indonesia: Initial insights into an underrecognized flavivirus threat
West Nile virus (WNV) is a mosquito-borne flavivirus primarily transmitted by Culex species and maintained in a bird–mosquito–bird cycle. Though WNV is not cons...
Exploring the crosstalk between the FGF/FGFR pathway and tumor microenvironment in clear cell renal cell carcinoma
Background In the phase 3 CLEAR study, lenvatinib plus pembrolizumab showed improved efficacy versus sunitinib for patients with clear cell renal cell carcinoma (ccRCC). Previous p...
Analysis of the importance and priority of male and female players in mixed doubles table tennis
To examine the relative importance and tactical priorities of male and female players in mixed doubles table tennis, this study analysed 35 matches involving world top-50 ranked players. A novel Five-...
Simultaneous transcatheter edge-to-edge repair (TEER) for severe mitral and tricuspid regurgitation is feasible, safe, and associated with good clinical outcome
Background Mitral regurgitation (MR) and tricuspid regurgitation (TR) commonly coexist in patients with heart failure (HF). Their concomitant occurrence carries a much poorer progn...
Correction: Effects of using standing desks for 45 minutes on the stress and executive function of elementary school students
Effect of whole-body vibration combined with exercise therapy on jump-landing stability after ACL reconstruction: A randomized controlled trial
This study examined whether incorporating whole-body vibration (WBV) into routine exercises enhances dynamic postural stability during jump-landing in athletes following anterior cruciate ligament rec...
Photo-based individual identification is more reliable than visible implant elastomer tags or toe-tipping in young agile frogs
In amphibian capture-recapture studies, commonly used individual-identification methods include toe clipping as well as less invasive alternatives of varying cost. Yet, choosing the best method for a...
Postpartum cytokine shifts and IL-10–mediated immune suppression in malaria-infected primigravid women
Background According to the World Health Organization’s recent report, malaria remains a major health challenge during pregnancy and for postpartum women in endemic regions. While...
Winners and losers in the platform revolution
This study investigates the success and failure of open platform strategies in enhancing firm profitability and value, extending prior research by Parker and Van Alstyne (2018) and Parker et al. (2017...