PLoS ONE
Articles in this Issue
Dispersion of LPG from spherical storage tanks: Power-law scaling and comparative analysis of LFL vs. 50% LFL
Liquefied Petroleum Gas (LPG) is typically stored in pressurized spherical tanks, where accidental leaks can create dense, flammable vapor clouds. This study used PHAST to simulate LPG dispersion from...
Editorial Note: Synergy between adaptations and resilience of livelihood from climate change vulnerability: A group-wise comparison of adapters and non-adapters
Does C-reactive protein exhibit high prognostic information value in acute pulmonary embolism? A novel structural pathway for disease progression beyond classical statistical associations
Acute pulmonary embolism (APE) is a life-threatening condition requiring precise risk stratification. Although numerous prognostic factors have been proposed, redundancy and limited predictive utility...
Reassessing the emergency department burden of influenza: A comprehensive real-world analysis using administrative data
Emergency departments (EDs) are burdened by high patient volumes during influenza seasons, yet the clinical and operational profile of influenza visits remains underexamined in large-scale data. This...
Repurposing antiviral agents against mucormycosis
Mucormycosis is a life-threatening fungal infection with limited treatment options and high mortality rates among immunocompromised individuals. To identify new therapeutic strategies, we screened a l...
Anomaly detection of cybersecurity behavior using cross-sequence aligned transformer—A dynamic recognition approach for high-frequency interaction patterns
In high-frequency interaction network environments, network traffic features and user behavior sequences often exhibit pronounced temporal asynchrony and information redundancy, which can substantiall...
Effects of dietary glutathione supplementation on the growth performance, nutrient digestibility, antioxidant function and intestinal morphology in growing male minks
This study investigated the effects of dietary glutathione (GSH) supplementation on growth performance, nutrient digestibility, amino acid digestibility, antioxidant capacity, and intestinal morpholog...
Association between social skills and mental health outcomes in Health Science Residents in Brazil
Residency programs play a crucial role in the development and technical training of young health professionals. However, mental health issues such as psychological distress, anxiety, and depression ar...
Optimizing nutritionally adequate food basket using linear programming in Niayes Households, Senegal
In Senegal, particularly in rural areas, diets are often monotonous and primarily based on cereals, with limited intake of animal proteins, vegetables, fruits, and dairy products. The COVID-19 pandemi...
Three-year functional, physical, and mental health outcomes after critical COVID-19: A prospective multicentre cohort study
Background The understanding of recovery after critical COVID-19 beyond the first year is limited. Objectives...
Longitudinal changes in circulating biomarkers from baseline to week 48 in treatment-Naïve people living with HIV initiating integrase inhibitor-based antiretroviral therapy
Background Currently, integrase strand-transfer inhibitors (INSTIs) are the cornerstone of antiretroviral therapy (ART), providing potent viral suppression and good tolerability. E...
Herbal medicine use and renal dysfunction among persons living with HIV on Tenofovir-based ART in Kampala, Uganda
Introduction HIV/AIDS remains a major public health issue, with about 1.4 million people infected in Uganda by 2020. In rural western Uganda, 57.6% of people living with HIV (PLWH)...
Artificial and natural selection components reveal the mechanisms of tropical sheep populations against gastrointestinal parasites
The infection by Haemonchus contortus is a significant challenge to sheep production in tropical regions, particularly in developing countries. Although several...
The association of maternal serum parameters with pregnancy induced hypertension in Chinese population
Background Abnormal changes of peripheral blood parameters were observed in women with pregnancy induced hypertension (PIH) as indicators of multi-organ involvement, but the clinic...
Environmental drivers of wild orchid distribution: Soil properties shape habitat preferences in the Po Delta Regional Park (Italy)
European terrestrial orchids inhabit a wide range of habitats, including forests, grasslands, wetlands and anthropogenic ecosystems. This study investigates the ecological preferences of seven wild or...
Assessing the sensitivity and predictive value of wastewater in detection of Hepatitis A cases in San Diego County
Hepatitis A virus (HAV) remains a significant public health concern in the United States. Because infected individuals shed virus through stool, HAV can be detected in wastewater. Shedding occurs prio...
AMR surveillance in Canada: Insights from the 2025 Priority Pathogen List
Background Antimicrobial resistance (AMR) remains a growing threat to public health and healthcare systems. In 2015, Canada published its first AMR Priority Pathogen List. In 2025,...
Normative Data for Learning and Memory Test (TAMV-I) in Latin American and Spanish Children: An item response theory and linear mixed models approach
Robust normative data for pediatric learning and memory tests in Spanish-speaking populations are scarce, and existing approaches often rely on univariate methods that overlook item-level properties a...
Hybrid passive micromixer using combined traditional microfabrication and 3D printing for gold nanoparticle synthesis
This study introduces a novel hybrid passive micromixer that seamlessly integrates conventional microfabrication techniques with cost-effective 3D printing to facilitate the controlled synthesis of na...
Optimising delivery of integrated palliative care and heart failure services: A realist evaluation protocol (PalliatHeartSynthesis II)
Background Inequality in palliative care provision is an ongoing problem for underserved groups, such as those with heart failure (HF) placing a burden on patients, their caregiver...
Noradrenergic innervation across brain regions is altered by aging and by disease progression in a mouse model of Alzheimer’s disease neuropathology
Norepinephrine plays critical roles in modulating arousal and attention, is highly dynamic in awake, behaving individuals, and has anti-inflammatory and neuroprotective actions. Notably, the locus coe...
Mapping potential community resources and care pathways for earlier identification and recovery-oriented intervention for people with psychosis in Addis Ababa, Ethiopia
Background There is a pressing need to reduce the long duration of untreated illness and improve care and outcomes for people with psychosis in Ethiopia. This study aimed to map co...
Editorial Note: Biochar enhances wheat crop productivity by mitigating the effects of drought: Insights into physiological and antioxidant defense mechanisms
Neighbourhood composition dictates expression of soil legacy effects on plant growth
Soil legacies, which reflect the influence of previous vegetation on soil biota and other properties, are increasingly recognized as drivers of current plant performance and community dynamics. Yet th...
Too much of a good thing? The moderating role of children’s perceived social support in drawing activities
Art engagement plays a crucial role in children’s flourishing, yet there is limited understanding of how individual traits and environmental factors shape children’s art engagement. Drawing on Cogniti...