PLoS ONE
Articles in this Issue
Expression of Concern: Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: Possible role of the Akt/GSK3β signaling pathway
Expression of Concern: The hidden costs of inflation: A critical analysis of industrial development and environmental consequences
Experiences of HPV self-collection among Aboriginal and Torres Strait Islander women and people with a cervix
Since July 2022, Australian guidelines have recommended that anyone eligible for cervical screening be offered a choice between using a self-collected vaginal sample or a clinician-collected cervical...
Long-term intensive golf training induces reconfiguration of brain structural covariance networks
Long-term motor training is thought to reshape brain organization, yet how golf expertise influences large-scale brain networks remains unclear. Using T1-weighted MRI and an individualized structural...
Associations between physical activity, fitness, cognitive and academic performance in Swedish adolescents: Findings from a cross-sectional study
Background Adolescence is a crucial phase for the development of cognitive abilities linked to academic performance. Factors such as physical activity (PA) and fitness have been hy...
Timed image naming evaluation for adults (TIME) using BOSS images
Normative data for naming photographs are essential in psycholinguistic research. However, image naming norms are typically derived from young adults, limiting their relevance for older populations, w...
Serological profile of naïve patients affected by the first sars-cov-2 variant: A prospective study
Background Understanding post-infection immunity with the first SARS-CoV-2 variant may provide valuable insights into the duration and effectiveness of the humoral immune response....
Interventions to improve mental well-being and sleep in paramedics: A scoping review
Background Paramedics face unique occupational hazards, including high operational demands, trauma exposure, and shift work, all of which impact mental well-being. Suboptimal sleep...
Similarity of sputum mediator signatures between e-cigarette users and COPD depends on GOLD stage and type of e-cigarette: a pilot study
There is overlap in symptoms and airway pathobiology between COPD and e-cigarette (e-cig) users. We sought to determine if young adult e-cig users have similar sputum soluble mediator profiles to COPD...
Correction: Research on energy-saving algorithm of HVAC multi-agent system consensus based on event-triggered mechanism
Leukotriene receptor antagonists and eosinophilic granulomatosis with polyangiitis: a disproportionality analysis from FAERS, JADER, CVAR databases integrated with network pharmacology
Objective The relationship between leukotriene receptor antagonists (LTRAs) usage and the subsequent occurrence of eosinophilic granulomatosis with polyangiitis (EGPA) remained hig...
Timing of therapeutic hypothermia and outcomes in neonates with hypoxic-ischemic encephalopathy: A cohort study in a middle-income country
Background Therapeutic hypothermia improves survival and neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy when initiated within 6 hours of birth. Howeve...
Identification of core genes mediating the association between obesity and hepatocellular carcinoma: A bioinformatics study based on mitochondrial metabolism and immune pathways
Purpose Obesity is strongly associated with hepatocellular carcinoma (HCC), yet the molecular mechanisms linking them remain unclear. This study aimed to identify mitochondrial met...
Dynamic simulation and intelligent control technology for cutting head load of coal mine roadheader
Due to the complex geological conditions of coal-rock, the cutting head of coal mine excavation machines experiences severe fluctuations in loads, making it difficult for existing macroscopic controls...
Forest fire detection and recognition method based on improved YOLOv5-ACE algorithm
Currently, forest fires have become a major fire safety issue. To detect forest fires and optimize the accuracy, a forest fire detection and recognition model based on an improved YOLOv5-ACE algorithm...
Quercetin prevents age-related hearing loss in C57BL/6J mice by activating mitophagy and inhibiting the NLRP3 inflammasome
Objective Age-related hearing loss (ARHL), the most prevalent sensory impairment in older adults, is closely associated with NOD-like receptor thermal protein domain-containing pro...
Mental health acts and out-of-hospital care: Legislative boundaries and the paramedic role in Australian mental health legislation
Background Changes to Australian mental health legislation have expanded the role of paramedics in managing mental illness. Paramedics in most Australian states and territories can...
Knockdown of miR-21-5P targets and regulates PDCD4-induced apoptosis in ovarian granulosa cells and ameliorates in sulin resistance in polycystic ovary syndrom
This study examined the role of miRNA-21-5p in a rat model of polycystic ovary syndrome with insulin resistance (PCOS-IR) and its potential involvement in ovarian granulosa cell apoptosis. Female Spra...
A prospective observational study of plasma concentrations and safety of combined intravenous lidocaine and epidural ropivacaine in laparotomy surgery
Intravenous lidocaine (IVL), an alternative to epidural analgesia (EA) for laparotomies, has demonstrated anti-inflammatory and anti-hyperalgesic effects. However, its combination with EA raises conce...
Unraveling the therapeutic potential of Elaeagnus angustifolia extract on triple-negative breast cancer (TNBC): An investigation using zebrafish model
Breast cancer is a widespread and aggressive disease, with 2.3 million new cases globally in 2022. Metastasis, the spread of cancer cells to distant organs, remains a leading cause of breast cancer-re...
Phosphorylations of serines 21/9 in glycogen synthase kinase 3α/β are dispensable for V600EBRAF-driven premalignant tumour development in the mouse intestine
Valine to glutamate substitution at residue 600 of the BRAF oncogene ( V600E...
Differential modulation of haematopoietic and oxidative injury by PARP-1 and ATR kinase inhibition in a murine model of acute irradiation
Temporal Modulation of Acute Radiation Injury by Post-Exposure PARP-1 versus ATR Kinase Inhibition. Background PARP-1 and...
Anisotropic mechanical properties of Dodecanophene nanosheets with pre-existing cracks by molecular dynamics simulation: Uncovering orientation- and temperature-induced variations
This work presents a comprehensive molecular dynamics simulation study investigating the anisotropic mechanical response and fracture mechanisms of defective Dodecanophene nanosheets, a novel two-dime...
Perception on blackflies and community ownership of the “Slash-and-Clear” vector control intervention in onchocerciasis-endemic communities along Edo-Ondo border in Southern Nigeria
Background Many communities along the Edo-Ondo border in southern Nigeria remain highly endemic for onchocerciasis. Despite more than two decades of mass drug administration (MDA),...
Invasive Argemone mexicana’s suppressive effects on germination and early growth of Triticum aestivum and Hordeum vulgare in South-western Saudi Arabia
The invasion of exotic plant species has emerged as a global problem that impacts the ecosystems, economy, and human health, and is the reason for biodiversity loss. Argemone mexic...