PLoS ONE
Articles in this Issue
Shining light on vitamin C deficiency and scurvy in Canada: A scoping review protocol of risk profiles, health outcomes, and interventions
Scurvy, resulting from vitamin C deficiency, is linked to serious health outcomes, including impaired collagen synthesis, anemia, and delayed wound healing. Once considered largely eradicated in high-...
Fine-grained identification of greenhouse crop leaf diseases based on reconstruction-generation network
There are few data labels in the agricultural field, and accurate annotation of existing data requires professional knowledge and is time-consuming and laborious, especially the images collected in th...
Myc and Skp2 overexpression promotes p27 ubiquitination and degradation in Ewing Sarcoma
Background Ewing sarcoma remains partially uncontrollable even after treatment with chemotherapy, surgery, and radiation therapy due to its high malignancy. To explore genes that d...
Non-destructive environmental DNA extracted from owl pellet contents: A valuable tool for monitoring mammalian species richness
Environmental DNA (eDNA) offers valuable presence/absence data for populations and has been widely used in comprehensive biodiversity assessments. However, applying eDNA in terrestrial environments po...
Exploring equity in audit and feedback trials: Secondary analysis of a systematic review
Background One potential approach to eliminating or reducing health inequities for health systems is audit and feedback (A&F). A&F involves providing measurements of qualit...
Correction: Concurrent coverage and determinants of vitamin A supplementation and deworming among children aged 12–59 months in 15 Sub-Saharan African countries
Modelling approaches for estimating vaccine effectiveness of consecutive SARS-CoV-2 variant sublineages in the absence of study-specific genetic sequencing data, VEBIS hospital network, Europe, 2023/24
Introduction Genetic changes in COVID-19 variants/sublineages (VSLs) can reduce vaccine effectiveness (VE). Timely VSL-specific VE estimates are essential, but study-specific VSL i...
Integrating machine learning with SHAP to uncover multi-tissue molecular signatures in Osteoarthritis progression
Osteoarthritis (OA) is a chronic joint disorder characterized by pain, reduced mobility, and structural degeneration. Despite its complex etiology and multi-tissue involvement, the molecular mechanism...
Factors correlated with financial hardship among cancer patients during the COVID-19 pandemic
Purpose Financial hardship from cancer care is associated with poor patient outcomes. Economic disruption during the COVID-19 pandemic may have exacerbated patients’ financial conc...
Psychophysiological effects of traditional cycling, virtual reality-enhanced cycling, and passive virtual reality exposure in young adults: A controlled within-subject study
Background Virtual reality (VR) offers a promising tool to enhance engagement in physical activity, but the independent and combined effects of VR on physiological and psychologica...
Correction: Exploring the potential of nest archives for establishing long-term trends in local populations of an Arctic-nesting colonial sea duck
Correction: Age-related changes in gait, balance, and strength parameters: A cross-sectional study
Spoken language and attitudes in Hong Kong: English leads in prestige, mandarin rises in employability, and Cantonese faces challenges
Language serves not only as a means of communication but also carries cultural, historical, and socio-economic implications associated with its speakers. These associations can reflect social dynamics...
Prevalence and associated factors of health facility delivery during COVID-19 in the Tamale Metropolis of Ghana: Analytical cross-sectional study
Introduction Globally, the COVID-19 pandemic significantly impacted the provision of maternal health services, especially facility-based delivery. However, there is little evidence...
Linear anti-jamming algorithm design for multi-channel optical fiber communication
The multi-channel fiber optic communication network, crucial for long-distance digital signal transmission, faces linear interference from orthogonal frequency division multiplexing. To address the ch...
Integrative network pharmacology and machine learning identify potential targets of indole-3-lactic acid in colorectal cancer
The treatment of colorectal cancer (CRC) remains challenging due to chemotherapy resistance and genetic heterogeneity. Indole-3-lactic acid (ILA), a tryptophan metabolite derived from gut microbiota,...
Reduced levels of mitochondrial ribosomal protein MRPL54 does not alter Apc related adenoma formation
Reprogramming of energy metabolism is one of the hallmarks of cancer cells and mutations that modify wild type intestinal cells to colon carcinomas increases cellular energy expenditure. Mitochondria...
Context-dependent dysregulation of store-operated calcium channels in head and neck squamous cell carcinoma
Store-operated calcium entry (SOCE), mediated by ORAI1–3 calcium channels and stromal interaction molecules STIM1 and STIM2, is increasingly recognized as a regulator of cancer progression. However, i...
Patient and injection partner perspectives on barriers and facilitators to home-based administration of long-acting injectable antiretroviral therapy
Long-acting injectable antiretroviral therapy (LAI-ART) offers an alternative to daily oral treatment but is typically administered in clinics, which can create barriers for some people with HIV (PWH)...
Analyzing and modeling public interest in fishery resources: Proposing flagship species for promoting sustainable fisheries in Japan
Effective management of natural resources fundamentally relies on public support, making an understanding of the dynamics of public interest crucial for successful conservation policy. Globally, fishe...
Evaluation of risk promoting effects for age-related macular degeneration by estradiol
Early menopause increases the risk for age-related macular degeneration (AMD), the most common cause of vision loss in industrialized countries. The supplementation with estradiol reduces the risk in...
Global, regional, and national burden of soft tissue and other extraosseous sarcomas, 1990–2021: A Systematic analysis for the global burden of disease study 2021
Background Soft tissue and other extraosseous sarcomas (STOES) are rare malignancies originating from mesenchymal tissues, posing a substantial health burden due to their aggressiv...
Retraction: Application of in-silico drug discovery techniques to discover a novel hit for target-specific inhibition of SARS-CoV-2 Mpro’s revealed allosteric binding with MAO-B receptor: A theoretical study to find a cure for post-covid neurological disorder
Vertical Jump and Isometric Strength in Professional Female Basketball Players: Starter vs. Non-Starter Comparison
This study examined whether differences in countermovement jump (CMJ) and isometric mid-thigh pull (IMTP) force-time metrics exist between starters and non-starters in professional female basketball p...