PLoS ONE
Articles in this Issue
Sociodemographic influences on Student Mental Health and their association with activation-regulating functional impairments
Activation-regulating functions, grounded in Executive Function Theory, Self-Regulation Theory, and the Dysexecutive (DEX) Framework, refer to higher-order cognitive processes such as task initiation,...
Prevalence of hyperprolific authors in sports medicine and musculoskeletal health and implications on research attention
Purpose The phenomenon of hyperprolific authorship has raised concerns about research quality, academic integrity, and the sustainability of publication practices across scientific...
Identification of novel plasma proteomic biomarkers of Dupuytren disease
Dupuytren Disease (DD) is a chronic progressive disease that can cause disabling hand deformities. The most common treatments have either high complication rates or high early recurrence rates. Dupuyt...
Computational design of functional random heteropolymers through atomistic simulations
Random heteropolymers (RHPs) are emerging single-chain nanoparticles with great potential in protein mimicry, yet a systematic understanding of how chemical composition and monomer structures govern t...
SegMan-based dual-prior network with boundary-augmented hybrid attention for robust skin lesion segmentation
Skin lesion segmentation is a crucial component of dermoscopic computer-aided diagnosis, yet challenges such as boundary ambiguity, morphological diversity, and noise interference under complex imagin...
Subjective and psychophysiological response to pictures of ancestral and modern threats: Not all evolutionary threats are alike
After encountering a potentially dangerous stimulus, the human body and mind might react with a cascade of physiological, emotional, and cognitive responses to minimize impending harm. However, whethe...
Exposure to parental depression in childhood and memory trajectories in mid- and later life
Little is known about whether childhood exposure to parental mental health problems, a significant stressor in early life, influences an individual’s memory trajectories in mid- and later life. Drawin...
Preparation and application of Taq DNA polymerase monoclonal antibody guided by structural domain analysis
Hot-start polymerase chain reaction (hot-start PCR) effectively inhibits non-specific product amplification during PCR, with hot-start Taq DNA polymerase (HS Taq) serving as the critical component. Cu...
Exploring the determinants of midwives’ perinatal bereavement support behaviour to mothers using the theory of planned behaviour in the Upper West Region of Ghana
Background Perinatal loss presents profound emotional challenges requiring skilled bereavement support from midwives. Despite its importance, determinants of midwives’ bereavement...
Contemporary Chinese newspaper discourse on translation: A mixed-methods approach to the People’s Daily (1949–2023)
Newspaper discourse on translation forms a particular discourse that uses newspapers as a medium to discuss the products, processes, and functions of translation. It can reflect how a society perceive...
Using national virtual maternal death reviews to improve the quality of care during Pregnancy, labour and birth, and Postpartum in Tanzania
Background Tanzania has implemented the Maternal and Perinatal Death Surveillance and Response (MPDSR) system for more than a decade. However, multiple assessments have shown that...
Seasonal variation in hospitalizations for peptic ulcer disease: A five-year retrospective study from Latvia
Peptic ulcer disease (PUD) remains a significant global health burden, yet data on seasonal variations in PUD hospitalizations are inconsistent across regions. No studies have assessed seasonal patter...
Data-driven p-norms for estimating transmission loss coefficients in power systems
This research introduces a novel convex methodology for estimating transmission loss coefficients ( B -coefficients) in power systems using a data-driven approa...
Malnutrition and female political representation in India
Malnutrition casts a negative shadow over the course of the lives of a fifth of children under the age of five who are stunted worldwide. Despite two decades of growth, India has one of the highest wa...
Effectiveness of routine tuberculosis education in a high-burden setting: A prospective observational cohort study
Background Low adherence to tuberculosis (TB) treatment remains a major driver of adverse health outcomes in high-burden countries. While guidelines recommend routine client educat...
How do hospital goals resonate with leaders, clinicians, managers, and patient and family partners? A critical discourse analysis of institutional logics
Introduction In pursuit of building person-centered health systems, patient and family engagement (PE) has emerged as a strategy to promote care quality, well-being, and patient ex...
Assessment of the compound impact of sea level rise, land subsidence and storm surge under climate change in ShangHai
Global climate change-induced sea level rise has emerged as a critical environmental challenge for coastal cities in the 21st century. Shanghai, China’s economic, financial, and shipping hub, faces si...
Prevalence of childhood polyvictimization, mental health outcomes, and associated risk and protective factors in Ethiopia and Uganda refugee settings
Background Children exposed to polyvictimization (exposure to multiple types of victimization), experience severe impacts on health and well-being across the life course. While the...
Exploring patient interpretation of an orthosis adherence checklist: A cognitive interview study
Upper extremity orthoses are commonly used in rehabilitation to reduce pain, improve alignment, and support return to daily activities. These benefits depend on regular and correct use, yet adherence...
Blockchain and federated Q-learning-based secure, fault tolerant, and energy efficient framework for ad hoc networks
An ad hoc network plays a critical role in enabling communication in environments where deploying fixed infrastructure is impractical or infeasible. However, their dynamic topology and decentralized n...
Antibacterial properties of experimentally produced birch tar and its medicinal affordances in the Pleistocene
Birch tar is well-documented for its use as an adhesive in the Middle Palaeolithic of Europe, but other uses remain poorly explored. Drawing from recent arguments suggesting multimodal uses of product...
Regulating ride-sourcing markets: Can minimum wage regulation protect drivers without disrupting the market?
Ride-sourcing platforms such as Uber and Lyft are prime examples of the gig economy, recruiting drivers as independent contractors, thereby avoiding legal and fiscal obligations. Although platforms of...
Implementing a successful patient navigation program for follow-up colonoscopy: Lessons from the PRECISE study
Background Colorectal cancer (CRC) screening using annual fecal immunochemical tests (FIT) is an effective strategy to reduce CRC incidence and mortality. However, nearly 50% of pa...
Effect of rhythmic auditory stimulation (RAS)® with and without melody on Parkinson’s disease (PD) patients with deep brain stimulation (DBS): A study protocol
Parkinson’s Disease (PD) is characterized by motor impairments, including gait abnormalities that contribute to instability and an increased risk of falls as the disease progresses. While deep brain s...
ABC-YOLO: Automated skin burn depth classification using YOLO architectures
Accurate classification of skin burn depth is vital for determining appropriate treatment and accelerating the healing process. This study conducts a comparative analysis of YOLO-based deep learning a...