PLoS ONE
Articles in this Issue
Hypochloremia, non-medication related associated factors, and impact on clinical outcomes in patients with acute heart failure: Insights from resource limited setups
Background Electrolyte disturbances such as hypochloremia are common in patients with acute heart failure (AHF) and may worsen clinical outcomes. However, data from low-resource se...
Lipidomic analysis of bile from patients with extrahepatic cholangiocarcinoma
Objective Cholangiocarcinoma and gallstones are significant gastrointestinal diseases with diverse etiologies and complex clinical manifestations. Understanding their underlying mo...
Expression of Concern: Enhanced surface plasmon resonance biosensor with graphene-black phosphorus heterostructure for ultra-high sensitivity refractive index detection with machine learning for behaviour prediction
Integrating biological and machine learning models for rainbow trout growth: Balancing accuracy and interpretability
Invasive species management demands predictive models that balance accuracy with ecological interpretability, yet traditional approaches often fail to capture complex environmental interactions. We ev...
Non-invasive host transcriptome and HPV oncogene expression map the molecular landscape of HPV-driven cervical lesions
Cervical cancer remains a significant global health burden. Current screening methods are not yet capable of detecting molecular alterations preceding cytological abnormalities. In this study, we perf...
Study protocol: Dental and periodontal characteristics of older adults in Atahualpa, Ecuador within the Atahualpa Project cohort
This study protocol describes an observational, cross-sectional investigation of oral health in community-dwelling older adults from Atahualpa, a rural village in Ecuador, embedded within the long-sta...
Strategic equity compensation: A delphi-AHP approach to industry-specific governance design for RSUs
This study views RSUs (Restricted Stock Units) as a strategic tool to achieve sustainable growth, shareholder value enhancement, and key talent retention, and proposes RSUs introduction and operation...
Antenatal depression and its relationship with birth outcomes and postnatal depression in Rural India: A longitudinal study
Background Depression is the most common mental disorder among women of reproductive age, with maternal depression the second leading cause of morbidity worldwide. Despite the seri...
Gene expression and metadata based identification of key genes for lung cancer, COPD, and IPF using machine learning and statistical models
Lung cancer (LC) is one of the most prevalent and deadly cancers globally, presenting a major public health challenge. Patients with chronic obstructive pulmonary disease (COPD) and idiopathic pulmona...
Correction: Home range and activity budget in the Falkland Steamer Duck (Tachyeres brachypterus)
Myofibrillar protein accumulation but reduced protein synthesis in PDCD4-depleted myotubes
Skeletal muscle is critical to whole-body functionality and homeostasis. The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) is a nutrient/growth-factor sensitive positive regulator of sk...
Evidence of allocentric spatial learning in male rats with large lesions of the hippocampus
The hippocampus (HPC) is the neural substrate of viewpoint-invariant cognitive maps, also known as allocentric spatial representations. Lesions of the HPC disrupt performance on allocentric tasks like...
Effects of similarity networks in graph-based multi-omics classification
Accurate classification of disease subtypes is a fundamental requirement of precision medicine especially for complex and heterogeneous conditions such as breast cancer and Alzheimer’s disease. Recent...
Genetic merit of sires for ad libitum residual feed intake has no adverse effects on carcass and ham quality traits of restricted-fed heavy pigs
This study evaluated the influence of sire genetic merit for residual feed intake (RFI) on carcass and ham quality traits in heavy pigs raised under the restricted feeding conditions typical of Protec...
“It makes me feel so much safer”: Sexual and gender minority community perspectives on telehealth use and implications for future practice
Introduction Telehealth has the potential to expand access to care, though barriers including insurance coverage, technology literacy, and personal preferences have been described...
Toxic chinese herbal medicine recognition in real-world images via multi-scale and attention-enhanced EfficientNetV2
Accurate identification of toxic Chinese herbal medicines is critical for public health and clinical safety. However, real-world herbal images often exhibit complex backgrounds and small, indistinct t...
Factors associated with patient adherence to medical recommendations during a health crisis
Introduction Patient non-adherence to medical recommendations is associated with significant economic and health consequences, particularly in chronic diseases. While less studied,...
Altitudinal and household breeding patterns of the medically important mosquitoes Aedes aegypti, Aedes albopictus and Culex quinquefasciatus in Nepal
Medically relevant mosquitoes have established populations across Nepal, adapting to diverse environmental conditions and altitudes. In addition to arbovirus vectors, the presence of...
Who cares about mental health? Benchmarking the issue importance of mental health for American voters”
Existing scholarship on public opinion and mental health in the US has emphasized variations in Americans’ stated support for policies or investments intended to address mental health. This work has s...
Expression of Concern: Schizophrenia as a Network Disease: Disruption of Emergent Brain Function in Patients with Auditory Hallucinations
Effects of increasing narasin doses on feedlot performance, feeding behavior, carcass traits, and rumen-cecum morphometrics in Nellore cattle
Narasin is an ionophore commonly used to improve energy efficiency and feed utilization in beef cattle. This study evaluated the impact of increasing levels of narasin on performance, feeding behavior...
Nutritional status and health of community-dwelling older adults in urban areas of the Lalitpur district, Nepal
Background Poor nutrition causes ill health and functional dependence in the older population. Different aspects of older people’s health and nutritional status are little known in...
Expression of concern: Optimizing load scheduling and data distribution in heterogeneous cloud environments using fuzzy-logic based two-level framework
Expression of Concern: Ensemble learning approach for advanced metering infrastructure in future smart grids
Trend of liver cancer attributable to alcohol use in China from 1992 to 2021: An age-period-cohort analysis study
Background & aims To analyze the dynamic trends of mortality, incidence, and disability-adjusted life years (DALYs) of liver cancer attributable to alcohol use in China from 19...