PLoS ONE
Articles in this Issue
Hypoxia- and inflammation-driven preconditioning modulates angiogenic and metabolic pathways in canine adipose-derived mesenchymal stem cells
The immunomodulatory properties of exogenous mesenchymal stem cells (MSCs) have been the target of research in immune-mediated diseases and organ transplants. However, the altered microenvironment dec...
Refining fibroblast-to-cardiomyocyte transdifferentiation protocols to explore emergent self-organization in cardiac cultures
Fibrotic scars post-myocardial infarction disrupt cardiac conduction, causing arrhythmias. We developed a minimized 4-component cocktail (CHIR99021/BMP4/Activin A/IWP2) for efficient fibroblast-to-car...
Global trends and forecasts of cervical cancer and a real-world safety assessment of human papillomavirus vaccines in women: A systematic analysis of the Global Burden of Disease study 2021 and the Vaccine Adverse Event Reporting System database
Background Cervical cancer (CCA) remains a major cause of morbidity and mortality among women globally, particularly in low- and middle-income countries. Although human papillomavi...
Clinical manifestations and cross-reactions between cockroaches and termites and identification of termites’ major allergens
The American cockroach ( Periplaneta Americana, CRa A) is a strong risk factor for allergic sensitization and asthma morbidity. Molecular phylogenetic studies d...
Correction: The impact of digital intelligence technologies on innovation performance: Evidence from specialized, refined, differential and innovative enterprises
Optimizing online teaching effectiveness in elementary education: Exploring multifaceted pathways based fsQCA analysis
The effectiveness of online teaching has emerged as a critical concern during the COVID-19 pandemic, with a particular emphasis on fostering a sustained interest in online instruction among educators....
Evaluating route preview as an alternative to turn-by-turn navigation in pedestrian mobility
Mobile navigation apps like Google Maps and Apple Maps predominantly use turn-by-turn (TBT) instructions for pedestrians, a paradigm originally designed for vehicular navigation. However, many users a...
App-supported versus conventional college physical education: Effects on standardized physical fitness scores and exercise motivation in Chinese university students
This study evaluated the effectiveness of an app-supported training model versus conventional physical education (PE) on college students’ basic athletic abilities and described exercise motivation in...
Retraction: Utilization of solid mine waste in the building materials for 3D printing
Retraction: Green fabricated zinc oxide nanoformulated media enhanced callus induction and regeneration dynamics of Panicum virgatum L.
Investigating the effects of continuous theta-burst stimulation over the posterior parietal cortex on holistic processing of composite faces: evidence from cognitive modeling
Efficient interaction with complex visual environments depends on the balance between global and local processing, with a natural tendency to prioritize global information—a phenomenon known as the gl...
The anti-infective potential of human milk oligosaccharides in carbohydrate powder in implant-associated infection with Staphylococcus aureus
Introduction Periprosthetic joint and implant-associated infections remain serious complications despite highly standardized diagnostic and therapeutic protocols. Repeated revision...
Reliability of durometry to assess firmness of calcinosis lesions in Juvenile and adult dermatomyositis
Background/Objective Dermatomyositis (DM) and juvenile dermatomyositis (JDM) are inflammatory myopathies affecting multiple organs, including muscle and skin. Calcinosis is a compl...
Identifying clinico-radiological determinants of post-stroke fatigue 3 months post-stroke in a French hospital-based cohort of non-severe stroke patients without psychiatric comorbidities
Post-stroke fatigue (PSF) is an overlooked and debilitating condition. As a multidimensional construct, fatigue encompasses physical, cognitive, and emotional components, complicating efforts to under...
Editorial Note: Green credit and market expansion strategy of high pollution enterprises—Evidence from China
A framework for objectively comparing competing invasion percolation models based on highly-resolved image data
Predicting gas migration in water-saturated porous media (a multiphase flow problem) is essential for applications such as carbon dioxide sequestration, hydrogen storage, and groundwater remediation....
Relationship between household attributes and contact patterns in urban and rural South Africa
Households play a crucial role in the propagation of infectious diseases due to the frequent and prolonged interactions that typically occur between their members. Recent studies have emphasized the n...
A smoothing and bootstrap-based framework for early outbreak detection
Timely detection of infectious disease outbreaks is critical for effective public health response. The effective reproduction number ( R...
The Women’s Wellness with Type 2 Diabetes Programme: Feasibility of an online peer support and goal-setting intervention for midlife women
Objective The Women’s Wellness with Type 2 Diabetes Programme (WWDP) is a complex intervention, encouraging positive lifestyle behaviours to enhance wellness outcomes. A previous f...
Numerical simulation of a hot-air cleaning fan for the combine harvester
This study aimed to improve the separation efficiency of damp crops by developing a hot-air cleaning fan. First, the aerodynamic performance of two fans with different inlet structures was compared. T...
The effect of dumping syndrome severity on health-related quality of life among bariatric surgery patients in Saudi Arabia
Dumping syndrome is a postoperative complication of bariatric surgery; it is classified into early and late dumping syndrome depending on the time of the symptoms. This study aimed to assess the healt...
Temporomandibular disorders among adult patients: Relationship with personality traits and other factors
Introduction Temporomandibular disorders (TMDs) refer to the pain and dysfunction of the temporomandibular joints and associated masticatory muscles. There is a lack of evidence ab...
Internal gene segments from a mouse-adapted influenza B virus confer increased pathogenicity to mice
Influenza B viruses (IBVs) contribute significantly to the annual influenza epidemics in human. Most IBV strains are non- or poorly pathogenic in mice, which are frequently used for vaccine studies. W...
Reliability and validity of the Sinhala version of the physical activity questionnaire for older children (PAQ-C)
Introduction In Sri Lanka, as non-communicable diseases rise, the significance of physical activity is increasingly recognised, particularly in children. The Physical Activity Ques...