PLoS ONE
Articles in this Issue
Channel reconstruction and dual attention dynamic fusion for remote sensing image semantic segmentation
As the spatial resolution of remote sensing imagery continues to be improved, the complexity of the information also increases. Remote sensing images generally have characteristics such as wide imagin...
A socio-ecological approach to the determinants of animal health management: A scoping review
With approximately 60% of human infectious diseases originating from zoonotic sources, an integrated approach to animal health management is critical. Significant barriers persist in optimizing diseas...
Prevalence and characteristics of scoliosis among ethiopian schoolchildren aged 6–15 Years: A school-based cross-sectional study
Background Scoliosis is a progressive spinal deformity that often develops during childhood and adolescence. In Ethiopia, population-level prevalence data are scarce, and school-ba...
Higher temperatures are associated with increased risk of police violence: A nationwide county-level study in the United States, 2013–2024
Ambient temperature has been demonstrated to be associated with a variety of violent or conflict events. However, few studies have so far linked temperature to the risk of police violence, where the q...
A nationwide survey on the prevalence of asbestos-related lung cancer in Japan
The nationwide prevalence of asbestos-related lung cancer (ARLC) needs to be accurately estimated to adequately operate a compensation subsidy program for patients with ARLC. In the present study, we...
Quantitative profiling of lifespan-dependent cell-cell communication potential reveals dynamic ligand-receptor network shifts across mouse tissues
Cell-to-cell communication (CCC) is a tightly regulated process essential for tissue development and homeostasis, but can become dysregulated during ageing. While CCC is inherently complex and remains...
Forecasting auditor’s going concern opinion using with hybrid robust machine learning model
The importance of forecasting company bankruptcies makes the auditor’s reporting of the going concern opinion (GCO) a focal point for interested parties. Therefore, researchers have recently turned to...
Feed management practices used for dairy cows in confined dairies in Brazil
Despite the critical role that feeding and feed bunk management practices play in dairy herd performance, limited information is available on how these practices are implemented across different produ...
A computational method to estimate the relative biological effectiveness and tumor control probability for low-LET proton irradiations
A constant relative biological effectiveness (RBE) value of 1.1 is used for proton therapy (PT) in many clinical treatment plans. However, several studies show that RBE varies with proton energy, line...
Comparison of CD34+ cell enumeration between flow cytometric analysis and ADAMII-CD34 image-based fluorescence cell counter
Background Accurate CD34 + cell enumeration is essential in stem cell transplantation. Flow cytometry (FC) is the...
Development of a survey and worry score to evaluate physician burnout and wellness interventions during COVID-19 in the Rio Grande Valley: A pilot study
Background Current research on physician burnout is limited in rural communities and physicians caring for the medically underserved. This study aimed to create an instrument to qu...
Assessment of compliance with quality laboratory standards in medical laboratories within the Kumasi Metropolis, Ghana
Background In Ghana, medical laboratories are a vital component of the health system, but there has been limited evidence on how well they meet international quality standards. Thi...
Pooled prevalence and co-occurrence of diarrhea and wasting and its associated factors among children aged 6–24 months in East Africa: Insight from recent demographic health survey: A multilevel analysis
Background Young children experiencing both diarrhea and wasting (DW) are at increased risk of severe malnutrition, impaired immune function, and greater susceptibility to infectio...
Sex differences in physical fitness among 10,000 adolescents aged 13–15 years
Physical fitness during adolescence is critical for health and sports participation, with sex-specific developmental trajectories influencing performance. The aim of this cross-sectional study was to...
What is the appropriate timing for advance care planning according to patients and their relatives? A scoping review
Background Advance care planning (ACP) is often initiated in the last phase of life. However, patients and relatives may need earlier conversations about their care preferences in...
Patient satisfaction among national health insurance enrollees in an accredited hospital of Kathmandu Valley: A cross-sectional, mixed methods study
Background The national health insurance program was piloted in 2016 in Nepal with a political commitment of reducing out-of-pocket expenditure and improving access to quality heal...
Machine learning of factors for improving oyster hatchery production
Oyster aquaculture and restoration in the Chesapeake Bay are vital, yet hatcheries frequently struggle with inconsistent larval growth and sudden mass mortality events. Unpredictable disruptions in la...
Visual analytics framework for survival analysis and biomarker discovery from gene expression data
We introduce a visual analytics methodology for survival analysis, and propose a framework that defines a reusable set of visualization and modeling components to support exploratory and hypothesis-dr...
The risk assessment of sleep duration on geriatric sarcopenia and its regulatory role in the effect of BMI index on geriatric sarcopenia based on the CHARLS database
Background The effect of sleep duration on geriatric sarcopenia remains unclear, and evidence of the combined impact of it and BMI on geriatric sarcopenia is scarce....
Exploring factors influencing parents’ adoption intention toward children’s illustrated e-books: A push-pull model perspective
With the development of multimedia technologies, children’s illustrated e-books are getting increasingly popular due to their diverse formats and engaging content. However, few studies have explored t...
Cancer risk associated with DPP4 inhibitors in type 2 diabetes: A pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS)
Background The use of dipeptidyl peptidase 4 (DPP4) inhibitors in treating type 2 diabetes mellitus (T2DM) is increasingly widespread. However, their association with malignancy ri...
Global COI meta-analysis reveals ocean-basin genetic structure in Sphyrna lewini
The scalloped hammerhead shark ( Sphyrna lewini ) is a circumglobally distributed apex predator clarified as Critically Endangered due to population declines ex...
Effect of maternal education on the literacy-numeracy development of children: A propensity-score matched analysis
This study examined the causal relationship between maternal education and children’s literacy-numeracy development in Bangladesh using nationally representative data from the Bangladesh Multiple Indi...
Visual self-assessment of dental appearance: A comparison of mirror types and digital reflection via smartphone front facing camera
Introduction In dental practice, patients often evaluate their own dental attractiveness using mirrors or smartphone digital reflections. This study aimed to investigate how mirror...
A theoretical and experimental model of flow characteristics in subretinal injections
Subretinal injections (SI) are used to deliver gene therapies for inherited retinal diseases, yet the optimal injection parameters remain undefined. This study used theoretical and experimental models...