PLoS ONE
Articles in this Issue
Measuring and valuing spillover effects in caregivers and families: A scoping review
Objectives As healthcare increasingly relies on informal care for chronic and complex conditions, economic evaluations have expanded beyond patient outcomes to consider spillover e...
Blocking heterochromatin spreading constrains cohesin binding at a yeast heterochromatic locus
Cohesin mediates central features of chromosome architecture. The protein complex governs sister chromatid cohesion and organizes genomes into loops and domains. In budding yeast, cohesin accumulates...
Palliative care follow-up for cancer patients combining day-hospital visits and telemedicine: What feasibility?
Background Due to the increasing life expectancy of patients with cancer, palliative care services are increasingly solicited to provide follow-up for individuals living at home. T...
Assessment of newly designed fonts for visual accessibility
Purpose The visual accessibility of fonts refers to the range of print sizes and efficiency with which readers can access text. One goal of font design may be to maximize accessibi...
Factors associated with Turkish individuals’ purchase of transportation, accommodation, and household services from digital platforms
Digital platforms are technological applications with steadily increasing popularity. This study aims to investigate various factors associated with the purchase of transportation, accommodation, and...
Utilizing large language models to construct a dataset of Württemberg’s 19th-century fauna from historical records
Constructing datasets on past biodiversity from historical sources is crucial for understanding long-term ecological changes. Typically, compiling such datasets relies on prior knowledge of the source...
An interdisciplinary rehabilitation program for adults with dementia—A randomized controlled pilot trial evaluating social participation, loneliness and mental health
Background To meet the complex needs of adults with dementia, a team-based, individualized rehabilitation approach may be required. This randomized controlled pilot trial evaluated...
Nickel price forecasting based onempirical mode decomposition and deep learning model with expansion mechanism
As a critical material for stainless steel production, electric vehicle (EV) batteries, and advanced technology alloys, nickel plays a pivotal role in the global energy transition, with its strategic...
Integrating natural gradients and controlled assays to reveal bacterial responses to cadmium in Theobroma cacao L., soils
Cadmium (Cd), a toxic heavy metal found in agricultural landscapes worldwide, has been pointed out in cropped soils with Theobroma cacao L., as one of the main...
Voiding symptoms aggravate with decreasing stromal/epithelial ratio and increasing glandular-epithelial content in patients undergoing laser enucleation for benign prostatic hyperplasia, independently from prostate size
Introduction Benign prostatic hyperplasia (BPH) includes epithelial, stromal and mixed hyperplasia, but their specific contributions to voiding symptoms and prostate volume (PV) ar...
Enhancing tensile strength of 3D-printed wood-PLA composites via a particle swarm optimization framework
In the evolving landscape of additive manufacturing, this study pioneers the optimization of FDM (Fused Deposition Modelling) parameters to enhance the tensile performance of eco-friendly Wood-PLA com...
Association between diabetes mellitus and impaired single-leg stance in patients with chronic liver disease: A cross-sectional study
Diabetes mellitus (DM) is highly prevalent among patients with chronic liver disease (CLD) and is associated with disease progression and complications. However, the impact of DM on physical function,...
Formulation and in-vitro functional evaluation of a Bacillus-based multi-strain probiotic consortium relevant to protein-energy malnutrition
Protein-energy malnutrition (PEM) remains a critical global health challenge, characterized by impaired nutrient absorption and chronic gut inflammation. While probiotics offer a potential therapeutic...
Improving the composition of donor milk using machine learning and optimisation techniques
Background and aims The macronutrient composition of donor human milk (DHM) can vary substantially due to several factors such as maternal age, diet, and lactation duration. Howeve...
Wild mushroom consumption susceptibility among Chinese university students: A machine learning study
Objectives To investigate factors associated with susceptibility to wild mushroom consumption using machine learning approaches and identify key predictors for targeted interventio...
The STRENGTH Study: A cluster randomised controlled trial of the effect of a behaviour change intervention added to cardiac rehabilitation on physical activity adherence
Background Coronary heart disease is the leading cause of global mortality, imposing significant health and economic burdens. Cardiac rehabilitation, including physical activity, c...
Unveiling hidden rocky reefs of the Mexican Atlantic coast: Topographic characterization and benthic community dynamics along the North Coast of the Yucatan Peninsula, Mexico
Rocky reefs are vital ecosystems hosting diverse benthic communities, including sessile organisms like algae, octocorals, and sponges, alongside associated fish and invertebrates, providing numerous e...
Correction: Development of an open-hardware semen homogenizer and application to serotonin effects on sperm motility
Correction: Research on multiple improvement paths of national innovation output based on tsQCA
Home over institution? New insights on older adults’ care preferences from a mixed-methods study in France
As populations age, long-term care policies must balance individual preferences with financial constraints. The prevailing “aging in place” policy in France assumes that citizens overwhelmingly prefer...
Retraction: The Effects of Matrix Metalloproteinase-9 on Dairy Goat Mastitis and Cell Survival of Goat Mammary Epithelial Cells
Prevalence and genotypic distribution of non-epidermolytic ichthyosis in Italian Golden Retrievers
Non-epidermolytic ichthyosis (NEI) is a hereditary skin disorder affecting several dog breeds, most notably the Golden Retriever. It is primarily caused by a loss-of-function variant in the...
Dynamic optimization of high-bandwidth multi-receiver signals for civil aircraft flight tests telemetry
Civil aircraft flight tests are distinguished by parallel multi-task operations, multi-sensor collaboration, and high-frequency data acquisition. The exponential growth in telemetry data generated in...
An integrated model of financial socialization, technology, and financial capability in predicting financial well-being
This study develops and empirically tests an integrated framework that explains how financial socialisation, technological factors, and financial capability jointly shape financial behaviour and in an...
HMGB1 reduce DNA damage by binding KU70 to activate NHEJ pathway in colorectal cancer cells after radiation
DNA damage-induced by radiotherapy is a critical factor in promoting the death of colorectal cancer cells (CRC). Although high mobility group box 1 (HMGB1) reportedly plays a vital role in tumor radio...