PLoS ONE
Articles in this Issue
Beyond the bamboo ceiling: How ethnic collaborative networks facilitate Chinese inventors’ knowledge remittances
Previous research on the “bamboo ceiling” has focused on how ethnic homophily limits career advancement for East Asian immigrants. However, less is known about how their ethnic collaborative networks...
Implicit association tests for all: Using iatgen for non-English and offline samples
The Implicit Association Test (IAT) has become an invaluable tool for researchers in many fields. The IAT is a sorting task that measures the strength of automatic associations between targets (e.g.,...
Utilization of the posterior iliac line for visualizing posterior column screws in obturator oblique view
Purpose To evaluate whether posterior column screws penetrate the posterior cortical surface of the acetabulum when assessed using obturator oblique radiographic imaging....
Evidence-based action plan for integrating artificial intelligence in an academic medical centre-a multidisciplinary approach
Introduction As the effectiveness of artificial intelligence (AI) in enhancing various facets of healthcare delivery becomes more apparent, it is anticipated that AI will soon find...
Ultra-high dose rate electron FLASH beam irradiation using a modified clinical linear accelerator
FLASH radiation therapy reduced radiation-induced damage to normal tissue, compared to conventional radiation therapy, and active studies have been undertaken worldwide. While a number of preclinical...
Multiomics profiling of zebrafish embryonic cell line PAC2 across growth phases to assess its relevance for toxicological studies
Permanent fish cell lines offer promising alternatives to traditional animal models for environmental risk assessment of chemicals. However, to facilitate broader uptake into toxicity testing practice...
Correction: Curated character of the Initial Upper Palaeolithic lithic artefact assemblages in Bacho Kiro Cave (Bulgaria)
Treatment sequence patterns of urate-lowering therapy in Korean patients with gout: A common data model-based study
Background A treat-to-target strategy involving treatment modification improves outcomes in gout, but evidence remains limited regarding the optimal approach when initial urate-low...
Evaluating the implementation and impact of the HEart faiLure carer support Programme (HELP) in the United Kingdom: A study protocol for a multi-centre, mixed-method, implementation study
Background Informal carers ( i.e., family members or friends) of patients with heart failure are ill-prepared and...
A pyroptosis-related gene signature for the diagnosis of acute pancreatitis
Acute pancreatitis (AP) is a severe inflammatory disorder in which pyroptosis—a pro-inflammatory form of programmed cell death—may contribute to pathogenesis. However, the complete transcriptional pro...
A protocol to establish and maintain organotypic cerebellar slice culture (OCerSC) from aged mice
Organotypic slice culture is a sophisticated technique historically used in cellular and developmental neurobiology to investigate three-dimensional architecture and cellular interactions. Maintaining...
A systematic review protocol: Efficacy and safety of nitrous oxide in analgesia in burn patients with dressing change
Background To alleviate pain in burn patients during dressing changes, it is necessary to identify an effective analgesic method. Conventional opioid analgesics have many limitatio...
SCGAN-generated skin-tone-balanced extension of the HAM10000 dataset for fairer dermatological AI
This dataset presents a synthetic collection of skin lesion images generated using a tone-conditioned Generative Adversarial Network (GAN) to model skin tone variation in dermatological datasets, moti...
Implementation fidelity of a community-based Aedes aegypti breeding site elimination program for dengue control in southeastern Mexico
Introduction Dengue is a globally significant arboviral disease in tropical regions such as southeastern Mexico. The “Healthy Environments and Communities” (...
SHPRH together with the Ube2D family of enzymes directly ubiquitinates PCNA at Lys164 in vitro
Ubiquitin-chain attachment to a highly conserved Lys164 residue in the proliferating cell nuclear antigen (PCNA) signals for template switching events to resume stalled DNA replication. In human cells...
Increased serum albumin corrected anion gap levels are associated with poor prognosis in sepsis-induced coagulopathy patients
Background Sepsis-induced coagulopathy (SIC) is associated with high mortality, and acid-base disturbances are common in critically ill patients with this condition. The anion gap...
Seroprevalence and altitude-dependent patterns of Toxoplasma gondii infection in livestock from northern Armenia
Toxoplasmosis, caused by the intracellular protozoan parasite Toxoplasma gondii , is a zoonotic disease affecting almost all warm-blooded vertebrates. Despite i...
Are routinely collected clinical and sociodemographic characteristics associated with social functioning and activities of daily living in schizophrenia? A machine learning approach descriptive of a schizophrenia cohort
Patients with schizophrenia often experience substantial impairments in social functioning and activities of daily living (ADLs). Previous studies have highlighted links between sociodemographic and c...
Correction: Critical risk identification in construction projects using 2D and 3D risk matrices
PDGFRα-positive mesenchymal stem/stromal cells contribute to autonomous vascular formation through in-body tissue architecture
Driven by endogenous platelet-derived growth factor receptor α (PDGFRα)-positive cells, in-body tissue architecture (iBTA) enables the autonomous formation of vascularized tissues within subcutaneousl...
Beyond silos: Drivers and barriers to intersectoral collaboration in zoonotic disease surveillance and response in the Greater Accra Metropolitan Area, Ghana
The One Health approach has gained global traction as a strategy to combat zoonotic diseases, which account for 60–75% of emerging infectious diseases. While effective surveillance requires intersecto...
Impact of age and clinical factors on the feasibility of mobile digital monitoring in people at risk of suicide
Objective Assessing the risk of suicidal outcomes is challenging, particularly in older people. Smartphone-based digital phenotyping may help to monitor suicide risk through ecolog...
Food safety practice and associated factors among food handlers working in food and drinking establishments in Debre Birhan City, North Eastern Ethiopia: A convergent parallel mixed-method study
Background Food-borne illnesses pose a major global public health threat, affecting up to 30% of people annually in higher-income countries and contributing to hundreds of thousand...
Mukara: A deep learning alternative to the four-step travel demand model with a case study on interurban highway traffic prediction in the UK
Accurate traffic volume prediction is essential for managing congestion, improving road safety, mitigating environmental impacts, and supporting long-term transportation planning. The traditional four...
Lack of tetrodotoxin analogues and individual metabolomic profiling of the cryptic frog Colostethus imbricolus
Poison frogs (Dendrobatoidea) are characterized by the great diversity of alkaloids discovered in their skin. However, most of these alkaloids have been found in brightly colored species and there is...