PLoS ONE
Articles in this Issue
Patients’ perception and needs of spiritual care: A qualitative study in the context of prolonged hospitalizations
Spiritual care is recognized as a core component of holistic nursing, particularly for patients experiencing prolonged hospitalization. Extended hospital stays may intensify spiritual needs by disrupt...
Reappraisal of profibrotic phenotype and cell-cycle state of renal tubular epithelium after ischemia–reperfusion injury
Chronic kidney disease progression involves phenotypic changes in tubular epithelial cells, and recent studies have highlighted the relationship between such pro-fibrotic phenotypes and cell cycle arr...
Prevalence of fungal infections in a patient cohort in The Gambia: Identification and characterization of three priority fungal species in patients with symptoms suggestive of TB
Invasive fungal infections are an increasing global health concern, particularly in low-resource settings where diagnostic capacity is limited. In The Gambia, where tuberculosis is highly prevalent, f...
Protocol for a randomized pilot trial of COMPASS, an open‑source, culturally adapted cognitive behavioral therapy program for forcibly displaced Venezuelan adults in Peru
Task-sharing approaches have shown promise in low-resource settings, yet few culturally adapted interventions have been systematically evaluated for forcibly displaced populations. Since 2016, over 1....
Targeted transferosomal delivery of cetirizine: A new approach to alopecia management
Introduction Androgenetic alopecia is common in males and females; its prevalence increases with age. It affects the social life of individuals worldwide. The main problem associat...
Associated factors of health-related quality of life in Indonesian Women with Systemic Lupus Erythematosus: A cross-sectional within-cohort analysis
Objective This study aims to determine the effects of sleep quality along with age, marital status, socioeconomic status, depression, anxiety, disease activity, pain scale, and dos...
Curability difference between autochthonous mouse tumors and their transplants in association with immune gene expression
Compared with transplanted tumors, autochthonous tumors are difficult to cure using experimental radiation therapy in mice. Here we analyzed differences in immune-related gene expression profiles betw...
BBR-n+ congestion control: Real-time performance with smart exit and advanced AQMs
The Internet is evolving rapidly, and billions of devices are being connected to it at the edge. Performance at the edge matters, and the role of the congestion control mechanism is important. Since t...
An optimized protocol for metabolic measurement in 3D tumor spheroids derived from primary and established glioblastoma cells
Tumors are characterized by a multitude of genetic and epigenetic alterations, including a deregulation of the metabolism, driving migration and infiltration. To mimic the energetic landscape of...
Mass casualty incident preparedness and response: A desk review of the Code Orange Plan and Assessment of Healthcare Workers’ Knowledge, Attitudes, and Practices in a Lebanese Tertiary Government Hospital
Background Effective preparedness and response to mass casualty incidents (MCI) are essential for hospital safety, operational efficiency, and the delivery of timely, high-quality...
Distinct tumor genomic signatures underlie canine macrophage polarization
Tumor-associated macrophages (TAMs) drive cancer progression and metastasis. However, the mechanisms by which tumor cells shape TAM phenotypes in canine cancers remain poorly understood. We investigat...
Comparative emission and energy performance of biochar production versus in-situ burning of Gorean agrobyproducts
Uncontrolled open-field burning of agricultural residues remains a pervasive source of air pollutants and greenhouse gases in Korea, particularly for high-burning-ratio crops such as perilla, pepper,...
Spatial distribution and determinants of unimproved sanitation facilities among households in Somalia: Using Somalia integrated household budget survey (SIHBS 2022)
Background Access to adequate sanitation remains a critical public health challenge in Somalia, where a large portion of the population relies on unimproved facilities due to persi...
Gut microbiome alterations among Ghanaian children with asymptomatic malaria infections
The human gut microbiome, consisting of bacteria, archaea, fungi, and viruses, influences various physiological processes of the body. The gut microbiome composition is shaped by factors such as diet,...
Prevalence of cancer related fatigue and its associated factors among adult cancer patients in eastern Ethiopia: A cross-sectional study
Background Fatigue is a frequent and distressing symptom experienced by patients with cancer. It may result from the disease process and/or its aggressive treatment, which substant...
Hierarchical coordinated scheduling algorithm for reactive power and voltage in cross-regional power grids based on multi-agent reinforcement learning
To address the challenges of strong dynamic coupling, action space dimension explosion, and voltage imbalance in reactive power and voltage scheduling of cross-regional power grids, this paper propose...
Stance modals in Chinese EFL learners’ monologue tasks: A corpus-based study
This study investigates how Chinese tertiary-level EFL learners used modals as linguistic devices for expressing stances in spoken English. Modals convey speakers’ commitment to propositions (epistemi...
Analysis of catabolic products of L-arginine; L-ornithine and L-citrulline and the residual L-arginine using the HPLC and LC-MS
L-arginine, a semi-essential amino acid, is metabolised in the cell to generate nitric oxide (NO) and L-citrulline via the enzyme nitric oxide synthase (NOS) or urea and L-ornithine via arginase activ...
PlantaNet and PlantaNetLite: Efficient and explainable multi-crop plant disease classification via transformer benchmarking and custom lightweight CNNs
Plant disease diagnosis based on visual symptoms is crucial for preventing yield loss; however, deployment in practical settings remains challenging due to inter-class similarity, background noise, an...
Development and validation of the MIPPE: A novel dyadic assessment tool for early parent-child interactions in clinical practice
Early parent-child interactions are crucial for child development. Existing assessment scales have several limitations: intensive training often exceeding 40 hours, administration time up to two hours...
Relationship between dietary thiamine, riboflavin, and niacin intake and hypertension subtypes: A cross-sectional study from the 1999–2023
Background This cross-sectional study aimed to investigate whether vitamin B intake (thiamine, riboflavin, niacin) influences different hypertension subtypes and which subtype exhi...
Voronoi tessellation as a complement or replacement for confidence ellipses in the visualization of data projection and clustering results
Visualizing two-dimensional data projections with group-wise coloring and confidence ellipses is a standard approach in biomedical data analysis. However, this method can obscure subtle group overlaps...
Robust finite-time anti-swing control for quadrotor slung-load system based on compensation function observer
In this work, a robust finite-time anti-swing controller is proposed for the quadrotor slung-load system subject to external disturbances. To stabilize the swing angles of the payload, an energy funct...
Correction: Formative research for a pre-operative psychosocial screening program for cardiac surgical patients: The EMBRACE study, a mixed methods knowledge to action protocol
Social capital and its influence on sustainable economic development and natural resource management among ethnic minorities in Phu Tho province, Vietnam
This study investigates the role of social capital in promoting sustainable economic development and natural resource management among ethnic minority communities in Tan Son and Thanh Son districts, P...