PLoS ONE
Articles in this Issue
Geographic inequities in human papillomavirus vaccine non-uptake and its determinants among adolescent girls in Ethiopia: Evidence from the National Immunization Survey
Introduction Human papillomavirus (HPV) vaccination has emerged as the most effective method for preventing cervical cancer. Despite this, Ethiopia’s HPV vaccine non-uptake rate re...
Camera traps reveal extensive anthropogenic impacts inside protected areas in Bangladesh
Camera traps serve as an essential tool for monitoring the wildlife habitat while simultaneously detecting and assessing various anthropogenic intrusions within protected areas (PAs). This study aims...
Fecal microbiota transplantation mitigates respiratory infection in rats exposed to hypobaric hypoxia by modulating the NLRP3 inflammasome and mucosal immunity
Objective To investigate the role of the gut-lung axis in respiratory infection under hypobaric hypoxia and the therapeutic potential of fecal microbiota transplantation (FMT)....
Integrated spatial-temporal feature alignment with graph convolutional and gated recurrent networks for traffic flow prediction
Accurate traffic flow prediction is essential for Intelligent Transportation Systems (ITS), yet capturing the complex spatiotemporal relationships within traffic data remains challenging due to dynami...
IGNN: An improved graph neufral network with integrated attention and pre-message-passing for few-shot image classification
Graph Neural Network (GNN) faces limitations in few-shot image classification due to insufficient adaptive feature extraction and limited long-range dependency modeling. To address these challenges, t...
Ecological patterns in the Porto-Novo Lagoon (Benin, West Africa): A review with implications for SDG 6.3.2 and EU-WFD readiness toward ecological status classification
Urban tropical lagoons provide vital services yet face nutrient loading, macrophyte blooms, and episodic hypoxia. This scoping review compiles four decades of hydromorphological, physico-chemical, and...
Fatty acid-binding protein 5 (FABP5) modulates limbal epithelial cell homeostasis by regulating the expression of key genes under both normal and inflammatory conditions, in vitro
Congenital aniridia, a rare disorder caused by PAX6 haploinsufficiency, is characterized by progressive, vision-threatening aniridia-associated keratopathy (AAK) with limbal epithelial dysfunction and...
Resilient nursing in ICU: Aadaptive practices beyond IPC protocols for MDRO management. A qualitative study
This descriptive qualitative study explores how resilience among intensive care nurses is activated during the management of patients with multidrug-resistant organisms and how it shapes adherence to...
Cytotoxicity in vitro assay in 3D vs. 2D L929 cell cultures – comparative analysis of the response to the latex extracts
The ISO 10993–5 recommends the cytotoxicity in vitro tests of the medical devices for the 2D cultures. The aim of the study was: – to develop the L929 cell cult...
Economic burden of pulmonary arterial hypertension in Switzerland
Objectives Pulmonary arterial hypertension (PAH) is a rare, progressive condition associated with high morbidity and healthcare resource utilization. This study aimed to estimate t...
Coaching past simple forms of habitual expressions beyond the textbook: A corpus-based experimental investigation
The present study was a nonequivalent pretest-posttest control group design investigating the effects of corpus-based instruction on grammatical accuracy and written application of past simple forms o...
Metagenomic and taxonomic profiling of phyllosphere bacteria from Mangifera indica in response to urban air pollutants in Medellín, Colombia
Urban trees and their phyllosphere-associated microbiota constitute a promising nature-based solution for mitigating urban air pollution. In this study, we characterized the taxonomic composition, div...
Primary liver cancer in Georgia: Seven years’ experience following the launch of the Hepatitis C Elimination Program, 2015–2022
Hepatitis C virus (HCV) infection is associated with hepatocellular carcinoma (HCC), the predominant form of primary liver cancer (PLC). In 2015, Georgia implemented the HCV Elimination Program to red...
How digital transformation in “diverse directions” activates enterprise total factor productivity: A mechanism study based on dynamic capability reconfiguration
Digital transformation is a key force driving high-quality economic development, yet the economic consequences of different digital technology directions vary significantly. Existing research often tr...
Expression of Concern: Detection of Plant DNA in the Bronchoalveolar Lavage of Patients with Ventilator-Associated Pneumonia
Correction: Annotation of nuclear lncRNAs based on chromatin interactions
Performance evaluation of the properties of gel patches based on the cross-linking reaction of partially neutralized sodium polyacrylate
Four types of partially neutralized sodium polyacrylate (PNSP) were prepared using two commonly used neutralization degrees of sodium acrylate/acrylic acid in molar ratios of 50/50 and 35/65. The perf...
ESKD from primary glomerulonephritis: Incidence and post KRT survival: A national cohort study in the UK
Background Primary glomerulonephritis (pGN) is a significant contributor to end-stage kidney disease (ESKD) and presents a significant healthcare burden. However, the epidemiology...
Evaluation and enhancement of suspected opioid overdose definitions in emergency medical services data using machine learning with natural language processing
Background Fatal and non-fatal drug overdoses have evolved into a critical public health crisis, with over a 50% increase in the rate of fatal drug overdose since 2019. Emergency M...
Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway
Sepsis-associated acute lung injury (SALI) is characterized by endothelial barrier dysfunction and capillary leakage. Ulinastatin (UTI), a serine protease inhibitor with recognized clinical benefits i...
Environmental DNA monitoring of waterfowl reveals community changes during migration
Large-scale monitoring of wildlife populations is a cornerstone of effective conservation and resource management, particularly for highly mobile taxa whose distributions shift rapidly across space an...
Personalized novelty-aware recommendation in social recommender systems: A Framework
This paper introduces a novel framework for improving social recommender systems by incorporating a personalized notion of item novelty grounded in user’s social interactions. Unlike conventional appr...
ATRX function beyond hippocampal CA1 is required for cognitive deficits in mouse models of intellectual disability
ATR-X syndrome, caused by mutations in the ATRX gene, leads to intellectual disability and neurodevelopmental deficits, with previous mouse models implicating f...
Task complexity in exoskeleton setup and takedown: Procedural steps and usability problems as predictors of deployment performance
Occupational exoskeletons show promise in reducing physical strain in industrial work, yet their industrial adoption remains limited. For exoskeletons to be used when performing tasks in industrial se...
Phenolic compounds from Arthrospira platensis and Chlorella vulgaris enhance growth, digestive function, antioxidant capacity, and immune-related gene expression in Nile Tilapia
Microalgae have many bioactive compounds as well as nutritional properties and have been used as a functional feed supplement to improve the health status of fish and their performance. Thus, the curr...