PLoS ONE
Articles in this Issue
Severity-dependent metabolic rewiring in COVID-19 based on untargeted metabolomic profiling of patient plasma
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a major global health challenge, characterised by a heterogeneous clinical spec...
Clinical and cost-effectiveness of the digital intervention, MyWay Diabetes, in people with type 2 diabetes living in Greater Manchester during the COVID-19 pandemic
Aims We aimed to assess a) whether using the digital intervention, MyWay Diabetes (MWD), during the COVID-19 pand...
Expression of Concern: Evaluation of the urban industrial coupling strategy based on the global production networks theory: A case study of the smart phone industry in the Guangdong-Hong Kong-Macao Greater Bay Area
Clinical practice teaching system for MNS cardiac rehabilitation: Delphi consensus
Background China faces a growing demand for cardiac rehabilitation professionals that outstrips available medical resources. While nursing master's candidates represent key talent...
Detection of Coxsackievirus A24v during an acute haemorrhagic conjunctivitis outbreak in Dar es Salaam, Tanzania, January-February 2024
Background In January 2024, an outbreak of acute viral conjunctivitis was declared in Dar es Salaam, Tanzania, following initial case clusters reported in December 2023 and continu...
Influence of fruit maturity and variety on seasonal postharvest fungal diseases and vascular streaking in California Avocados
This study evaluated the avocado varieties ‘Hass’, ‘GEM’, ‘Luna UCR’, ‘Eugenin’, ‘Flavia’, I27EG, I55B, I49LB, I54J, and I73WL to determine seasonal dry matter (DM) patterns and assess how harvest tim...
Tracking the narrative: A data-driven analysis of media coverage of Russia and Ukraine 2013–2024
This study addresses the lack of global, long-term analyses of media narratives on Russia and Ukraine by examining their evolution from 2013 to 2024. Based on 22.2 million article titles from 14,622 s...
Regional VRE surveillance using routine centralised, multicentre whole genome sequencing
Objective Whole genome sequencing (WGS) is increasingly used to support infection prevention and control. However, its application for routine regional surveillance of vancomycin-r...
Enhanced IGFL1 translation in response to IL-1β is controlled by distinct 3’UTR elements
Translation is a crucial regulatory mechanism involved in several diseases, including cancer, where pro-inflammatory conditions within the microenvironment have been shown to modulate the translation...
Isoginkgetin increases the expression of metal responsive transcripts but inhibits their translation
Isoginkgetin (IGG) is a natural bioflavonoid isolated initially from leaf extracts of Gingko biloba trees used in traditional Chinese medicine. We previously re...
Analysis of brain network temporal reconfiguration and frequency-domain features during dynamic orchestral segmentation transition based on electroencephalography
Background/Objectives: The human brain’s natural capacity for music perception relies on dynamic interactions across distributed neural systems. To understand this process, we investigated how the bra...
Trends and risk factors of patient falls in Korean hospitals: A five-year national reporting data analysis
Patient falls are among the most frequent and preventable patient safety incidents in hospitals, often resulting in serious injury, prolonged hospitalization, and increased medical costs. Despite the...
In silico screening and molecular analyses identify apigenin from Scutellaria barbata as a potent AKT1 inhibitor in breast cancer
Breast cancer (BC) remains a leading cause of cancer-related mortality in women worldwide. Scutellaria barbata , a traditional Chinese medicinal herb, possesses...
Ego-resilience and health-related quality of life after acquired Upper Limb Amputation
Purpose The purpose of this study was to examine the relationships between demographic variables, ego-resilience and health-related quality of life (HRQoL) for individuals with upp...
The mediating effect of burnout on the relationship between workplace culture and intent to stay among registered nurses in Saudi Arabia
Background Nurse turnover is a critical challenge to healthcare quality in Saudi Arabia, yet the mechanisms linking workplace culture to retention intentions remain unclear. While...
Artificial Intelligence in emergency department triage: A scoping review
Background Triage in emergency departments (ED) is a critical process for prioritizing care and ensuring clinical safety. However, current triage systems often exhibit vulnerabilit...
Factors associated with the coexistence of anemia and undernutrition among children aged 6–59 months in Mali, 2023/24: A multilevel mixed-effects analysis
Introduction coexistence of anemia and undernutrition is a major public health concern among children in Mali. However, there is a lack of study looking into the relationship betwe...
Relationships between gene expression variability, expression levels, and Protein–Protein interactions in mouse and yeast
Understanding how evolution shapes variability in gene expression is complicated by the interdependence of expression levels, expression variability, and evolutionary rates. Metrics that quantify vari...
Speed guidance strategy at intersections based on platoon recognition in connected and autonomous vehicles environments
To alleviate the issues of widespread traffic congestion and low passage efficiency at urban signalised intersections, which result in increased vehicle energy consumption, this paper proposes a speed...
Editorial Note: Drug prescriptions preceding opioid-related deaths–a register study in forensic autopsy patients
Psychosocial factors associated with engagement and efficacy of mindfulness intervention in the classroom
Background Mindfulness practice has been associated with a range of benefits in the literature. However, intervention effects show substantial person-to-person variability, and the...
The expert’s cadence, the novice’s rush: A multi-level analysis of cognitive rhythm in translation production under pressure
This study examines how time pressure and translator experience interact to shape the cognitive rhythm of translation production. Sixty-five Chinese-English translators’ (35 novices, 30 experienced) k...
Correction: Where do they come from and where do they go: Understanding the relationship between deprivation and the geographical journeys of trainee doctors in England
Assessing undergraduate mentoring competency in a research-intensive Hispanic serving institution: A revalidation
Mentoring is a critical factor in fostering persistence and professional identity among undergraduate students from underrepresented minority (URM) backgrounds in STEM. However, the systematic assessm...
Evaluation of stream visual assessment protocol with measured water quality parameters in urban streams
Accurate assessment of stream health is important due to the numerous known influences of habitat, including water quality, on aquatic ecosystems as well as human health. The Stream Visual Assessment...