PLoS ONE
Articles in this Issue
Microscopic simulation of free riding speed dynamics in bicycle traffic: Modeling heterogeneous context-dependent effects
Simulation is a valuable tool for traffic planning that requires reliable modeling of traffic dynamics. Free flow speeds in bicycle traffic depend on the characteristics and preferences of the bicycli...
An approach of dual attention-driven multi-levelled graph neural architecture for rich-structural social graph analysis and representation learning
In recent years, graph neural networks (GNNs) have emerged as a dominant paradigm for learning from graph-structured data, achieving strong performance across a wide range of graph mining tasks, inclu...
Detection of non-invasive sexing of early chick embryos in intact eggs using laser speckle contrast imaging and deep neural networks
The ability to image blood flow in early-stage avian embryos has significant applications in developmental biology, drug and vaccine testing, as well as determining sex differentiation. In this projec...
The individual and combined effects of air pollution mixtures on the risk of cardiovascular diseases in patients with Cardiovascular-Kidney-Metabolic syndrome at stages 0–3
Background This study aims to employ a prospective cohort design to quantitatively assess the association between exposure levels of common ambient air pollutants and the risk of c...
Framing the world: Strategic narratives of foreign states in China’s mainstream media (1950–2019)
This study investigates how mainstream Chinese media have portrayed foreign states over the past seven decades. While scholars have extensively studied foreign media portrayals of China, little system...
Acute effects of intermittent hypoxia–hyperoxia exposure on cardiovascular autonomic function and blood pressure in sedentary older adults: A pilot randomized controlled trial
Background The aim of this study was to evaluate the acute effects of a single session of intermittent hypoxia–hyperoxia exposure on cardiovascular autonomic regulation, blood pres...
Emergency department visits and disease patterns during and after the COVID-19 lockdown
Background The COVID-19 pandemic caused significant disruptions in healthcare systems worldwide, particularly in emergency department (ED) utilization. While much research has focu...
Determinants of dropout from lifestyle interventions for overweight polycystic ovary syndrome: An exploratory analysis of randomized controlled trial
Objective This exploratory analysis of a randomized controlled trial aimed to identify baseline predictors of dropout in overweight women with polycystic ovary syndrome (PCOS) part...
Integrated NEK7-inflammasome and platelet transcriptomic signature generates mechanistic hypotheses in heart failure
Background The relationship between NEK7-NLRP3 inflammasome activation and elevated platelet activity in the progression of heart failure (HF) is not well understood. Additionally,...
Comparative performance of invasive, semi-invasive, and non-invasive insulin resistance-related indices across prediabetes and normoglycemia
Insulin resistance, a defining abnormality in the development of type 2 diabetes, often emerges silently during prediabetes. This study evaluated the comparative performance of multiple insulin resist...
Assessing reader reception of Arthur Waley’s English translation of Journey to the West: A topic modeling and sentiment analysis approach
Arthur Waley’s 1942 abridged translation, Monkey: Journey to the West , remains one of the most influential and widely debated English renderings of this Chines...
Situated generosity in clinical care: A mixed-methods study of STI services in China
Background Generosity is a critical yet understudied dimension of prosocial behavior in healthcare. Existing research has focused on individual traits or professional values, with...
Potentials and challenges of next generation sequencing-guided individualized treatment for management of rifampicin-resistant tuberculosis – A qualitative study
Background Next generation sequencing (NGS) is a powerful technology for diagnosing and managing rifampicin-resistant tuberculosis (RR-TB). To facilitate its integration into routi...
Role and mechanism of nitric oxide-regulated cGAS/STING pathway-mediated inflammatory response in hypoglycemia-induced coronary artery endothelial cell injury
Background Hypoglycemia in diabetes markedly increases the risk of coronary artery events, but the mechanism by which it damages vascular endothelium through nitric oxide (NO) regu...
Optimized passive thermoelectric temperature regulation for dust-resilient sensor nodes in Extreme Desert Climates
Autonomous sensor nodes deployed in harsh, remote desert environments face significant reliability challenges due to extreme diurnal temperature fluctuations. This paper presents an Optimized Passive...
Integrated in silico and in vivo larvicidal evaluation of compounds targeting juvenile hormone for malaria vector control
Malaria remains a major global health challenge, particularly in sub-Saharan Africa, where it is a leading cause of morbidity and mortality. Inhibition of the mosquito juvenile hormone binding protein...
Nitrate contamination characteristics and health risk assessment of groundwater in the typical area of the lower Yellow River Basin
Nitrate is a key indicator for assessing groundwater quality, and nitrate pollution in groundwater poses a threat to water security and ecological health in the Yellow River Basin. Taking the Changxia...
Knowledge, attitudes, and practices toward artificial intelligence among health sciences students: A cross-sectional study in Palestine
Background Artificial intelligence (AI) is increasingly integrated into healthcare education and clinical practice. Understanding health sciences students’ knowledge, attitudes, an...
Association of SARS-CoV-2 infection with incident diabetes among U.S. Veterans in a prospective longitudinal cohort
Objective To assess care-seeking patterns and incident diabetes risk following SARS-CoV-2 infection in a prospective longitudinal cohort....
Understanding the drivers of modern contraceptive use trend change and inequalities among sexually active women in Lesotho: A decomposition analysis (2004–2023)
Background Improving utilization of contraceptive methods serves as a powerful catalyst for advancing women’s education, health, and personal autonomy. Many countries have pledged...
Correction: Comparative metabolic profiling, enzyme inhibitory activities, and in-silico analysis of the hexane extract and the hydrodistilled oil of Boswellia serrata
Tracking rehabilitated sea turtles in the Indian Ocean using satellite telemetry: Insights into behaviour, ecology, and conservation implications
Understanding the movements and behaviour of threatened marine turtles is essential for effective conservation management. Satellite telemetry is a valuable tool which has previously provided valuable...
Effects of 12-weeks of Brisk Walking on Health-related Physical Fitness, Balance, and Life Satisfaction in Overweight Older Chinese Women: A Cluster Randomized Control Trial
Obesity among the elderly is primarily the result of a lack of exercise. Many people around the world are concerned about how physical activity can improve the life satisfaction and physical health of...
Plasma C5a and serum C5aR levels in patients with chronic spontaneous urticaria: A single-center case-control study
Background C5a and its receptor, C5aR, are involved in the degranulation of mast cells and basophils, leading to the release of proinflammatory cytokines. However, to date, their r...
Why do people comply with health guidelines in a competing information environment?
The COVID-19 pandemic unfolded in parallel with an infodemic where competing information from formal and informal sources shaped protective behavior. This study conducted a secondary analysis of cross...