PLoS ONE
Articles in this Issue
Growth, instability and future outlook of livestock population and products in Bangladesh
In the changing agri-food system, livestock play an important role, providing not only protein and micronutrients but also organic fertilizers, employment, and women’s empowerment in many developing c...
Transcranial direct current stimulation in affecting neuropsychiatric symptoms of post-COVID syndrome: No change in microstates and functional connectivity
Introduction Neuropsychiatric symptoms of post-covid syndrome (PCS) involve fatigue, brain fog, cognitive impairment, or symptoms of depression and anxiety. These symptoms are in o...
Downregulation of SLC44A4 in nasopharyngeal carcinoma is associated with malignant progression, B-cell/TLS-related immune features, and sensitivity to DNA-damaging agents
Nasopharyngeal carcinoma (NPC) is characterized by aggressive progression, frequent metastasis, and heterogeneous therapeutic responses. Through integrated bulk transcriptomic datasets, single-cell an...
Further evidence for embodied cognition: The link between spontaneous respiratory oscillations and number processing
Embodied accounts of cognition propose that bodily states shape mental representations. We test this proposal in numerical cognition by asking whether spontaneous respiration biases random number gene...
Seed disperser connectivity in a heterogeneous landscape of the Colombian Coffee Region
Habitat fragmentation is a major threat to biodiversity in tropical montane ecosystems, where limited forest cover and steep elevational gradients can strongly constrain species movement and connectiv...
Long-term effects following prenatal cocaine exposure: A systematic review
Cocaine use represents a global public-health concern, and children’s exposure to this substance is receiving growing attention. Despite the importance of this phenomenon, efforts to isolate cocaine-s...
A collaborative cervical precancer screening strategy with concurrent HPV genotyping and visual inspection using alumni of a training centre across Ghana: The Rotary ‘Protect Your Pearl’ initiative
Background Cervical cancer is a leading cause of cancer mortality among Ghanaian women, yet screening uptake is under 5%. The Cervical Cancer Prevention and Training Centre (CCPTC)...
Identifying gene regulation modules associated with tumor metastasis using a network decomposition approach and combinatorial fusion analysis
We systematically evaluated whether modular decomposition of molecular networks into gene regulatory modules (GRMs) enables the identification of metastasis‑associated genes. We developed an efficient...
Multisystem frailty phenotypes and associated factors among older adults in Türkiye: A nationally representative study
Multisystem frailty, characterised by concurrent decline across motor, sensory, cognitive, and functional domains, remains a relatively understudied phenotype within ageing research. Evidence on its p...
Standalone bio-interventional uveoscleral outflow enhancement for intraocular pressure reduction in open-angle glaucoma: One-year results from a prospective multicenter real-world evidence study (NCT05506423)
This prospective, multicenter, real-world evidence study evaluates the 12-month safety and effectiveness of standalone cyclodialysis with AlloFlo™ cleft reinforcement for intraocular pressure (IOP) re...
Inpatient mortality and associated clinical factors among people living with HIV with cryptococcal meningitis in Uganda: A retrospective cohort study
Introduction Cryptococcal meningitis remains a leading cause of HIV-related mortality in sub-Saharan Africa despite expanded antiretroviral therapy coverage. Evidence on the burden...
Optimizing an ethanol-based fixative for enhanced nucleic acid preservation in cervical samples using a central composite design approach
Background To accurately diagnose cervical cancer, high-quality genetic material (DNA and RNA) from clinical samples is crucial. Current preservation methods often have limitations...
Adaptive robust sparse representation for face recognition based on weighted and fusion dictionary
We propose a new model for face recognition under insufficient sampling conditions in this paper. In the proposed method, we combine the fusion dictionary with nuclear norm regularization to preserve...
Immunosuppressive regimens and long-term kidney transplant outcomes: A dual survival modeling framework
Optimizing immunosuppressive therapy remains central to improving long-term outcomes after kidney transplantation. Both induction and maintenance therapies are widely used, yet their comparative effec...
Integrated application of meat waste-derived organic fertilizer and chemical fertilizer in sugarcane cultivation
Slaughterhouse waste is a major source of environmental pollution. However, its rich organic content holds considerable potential for enhancing soil fertility. Herein, slaughterhouses meat waste was u...
A curriculum-integrated sun safety intervention to improve adolescent skin health knowledge in an independent girls’ secondary school
Australia has one of the world’s highest melanoma incidences among youth. Adolescents often under-prioritise sun protection due to sociocultural factors, for example, the perceived attractiveness of t...
Understanding smart home automation acceptance through users’ lifestyles and perceived difficulty of use: Evidence from South Korea
Smart home automation (SHA) is an advanced service that automates household tasks with minimal human intervention, enhancing efficiency, convenience, and personalization. SHA serves as the critical br...
A mixed-methods analysis of the implementation of a new community long-COVID service during the 2020 pandemic: Learning from practice
Introduction The rapidly increasing prevalence of long-COVID (LC), a condition characterised by multisystem complexity and high patient symptom burden, posed an immediate need to d...
Determinants and predictive modelling of barriers to HIV testing uptake among adolescents and young adults in a private higher education institution in Botswana
Background HIV represents a significant public health challenge, contributing to increased mortality and morbidity in developing countries, particularly Sub-Saharan Africa. While H...
Artificial intelligence-based prediction of diseases among homeless populations in Bogotá: Implications for targeted interventions
Background The homeless population in Bogotá exhibits complex social and health vulnerabilities, with a high prevalence of chronic and communicable diseases such as hypertension, d...
Factors associated with the duration of telephone observation and consultation sessions provided by the Hiroshima Prefecture Follow-up Center in the later stages of the COVID-19 pandemic in Japan
Background Identifying the factors that affected the workload of Public Health Centers (PHCs) during the recent COVID-19 pandemic may help such institutions improve their preparedn...
Comparison of two algorithms of APTT-based lupus anticoagulant assay, two Dilute Russell viper venom time reagents, and silica clotting time
Lupus anticoagulants (LA) are heterogeneous antiphospholipid antibodies that interfere with phospholipid-dependent coagulation assays, resulting in considerable variability among detection methods. Al...
Health outcomes and healthcare delivery systems for pregnant and postpartum individuals in immigration detention settings: A scoping review protocol
Pregnant and postpartum individuals in immigration detention may experience barriers to accessing timely and appropriate perinatal care. The existing literature remains fragmented across global settin...
Editorial Note: Design and implementation of a graphene–polyimide-based H-slot terahertz antenna for wireless and biomedical applications
Cannabis use, sexual behaviors, and HIV prevention behaviors among young adults attending key-population-led sexual health clinics in Bangkok, Thailand: A mixed-method study
Background The intersection of cannabis and sexual behaviors poses important public health concerns, particularly following Thailand’s cannabis decriminalization. However, evidence...