PLoS ONE
Articles in this Issue
COVID-19 alert level systems—Lessons learnt for future public health emergencies: A qualitative study
Background During the COVID-19 pandemic, Alert Level Systems (ALS) were widely implemented as public health tools to communicate risk levels and recommend public health and social...
Knowledge, attitudes, and practices regarding asthma management among pharmacists in palestine: A cross-sectional study
Background Pharmacists can play a key role in asthma management through patient education, inhaler technique assessment, and promoting evidence-based care. This study assessed Pale...
The validity and reliability of a biometrically accurate, photorealistic set of young adult body size scales based on 3D scans of White Europeans
Young adults are a high-risk group for weight-related health problems but are often overlooked in weight management intervention design. Validated visual tools that accurately depict body size are nee...
Leaf beetle diversity on a Southeast Asian continental island: Taxonomy, DNA barcoding, and preliminary evolutionary insights from Cat Ba Island, Vietnam
Continental shelf islands in Southeast Asia remain poorly studied with respect to insect diversity and evolutionary history. Here, we provide an integrative assessment of species diversity, DNA barcod...
Optimized feature selection and zero-parameter channel attention BiLSTM for RPL-attack classification in IoT networks
The increasing adoption of Internet of Things (IoT) devices introduces significant security challenges, particularly in networks based on the Routing Protocol for Low-Power and Lossy Networks (RPL), w...
Thyroid V40 as a potential early predictor of hypothyroidism following hypofractionated locoregional breast radiotherapy
Radiotherapy (RT) is used quite often among breast cancer patients, and because these patients now live longer than they used to, long-term treatment-related adverse effects, such as hypothyroidism, a...
Hybrid quantum-classical neural networks for real-time fault detection in power systems
As modern power systems continue to be integrated with renewable energy sources, the ability to detect faults in these systems quickly and accurately is becoming more sophisticated. A Hybrid Quantum C...
Visual and textual cues in online presentations of natural foods are associated with taste inference and cognitive engagement
Digital environments have become important contexts in which consumers form sensory expectations and evaluate food quality prior to consumption. Drawing on the elaboration likelihood model and attribu...
Correction: The Covid-19 pandemic in Sweden: Prolonged and unevenly distributed effects on the volume of pediatric anesthesia and surgery demonstrated by data from the Swedish Perioperative Register
Attitudes and Behaviors toward traditional music among Chinese students: the role of individual, family, and school factors
Background Traditional music is vital for cultural identity, particularly among youth in China, yet factors influencing students’ engagement with it remain underexplored....
Comparative analysis of gut microbiome alterations in early- and late-onset preeclampsia: A case control study
Preeclampsia (PE) is a complication during pregnancy characterized by hypertension, organ damage, and systemic inflammation. Increasing evidence suggests that the gut microbiome may play a role in the...
Focus shifts in contextual and lexical cue interactions in GPT models
Transformer-based language models have demonstrated sensitivity to a range of linguistic dependencies, yet it remains unclear how they represent information-structural focus and integrate discourse an...
Start order and medal outcomes: An analysis of apparatus finals in men’s artistic gymnastics
Purpose This study examined the relationship between start order and competition outcomes in men’s artistic gymnastics apparatus finals....
HIF-2α drives osteoarthritis progression via suppression of the HDAC4-ATF4-CHOP signaling axis
Hypoxia-inducible factor-2α (HIF-2α) is a key regulator of cellular adaptation to hypoxia, but its role in osteoarthritis (OA) remains incompletely defined. This study aimed to investigate the contrib...
Protocol for a qualitative mechanistic study of MDMA with a sample of psychoanalytic psychotherapists: A phenomenological investigation
Introduction Methylenedioxymethamphetamine (MDMA)-assisted psychotherapy (MDMA-AP) is a potentially transformative intervention for post-traumatic stress disorder (PTSD). Despite e...
Whole-genome characterization of halotolerant Enterobacter roggenkampii OSNO4 and its potential for climate-resilient agriculture
Plant growth-promoting rhizobacteria (PGPR) represent an eco-friendly strategy to improve crop yield under abiotic stress conditions. This study aimed to perform a comprehensive genomic and functional...
Evaluation of steroids for acute COVID in the prevention of long COVID in children: An EHR and pediatric cohort study from the RECOVER Initiative
Background Studies have shown that use of immunomodulators during the acute phase of SARS-CoV-2 infection may decrease development of post-acute sequelae of SARS-CoV-2 (PASC) or lo...
Multi-scale closed-loop tuning via spatial frequency collaborative sensitivity for rice leaf disease detection
Rice is a fundamental food source for more than half of the global population, making stable yields and quality improvements vital for food security and sustainable agricultural development. Early inf...
Trends and spatial distribution of low-level viremia among Ugandan children and adolescents, 2014–2023
Background Low-level viremia (LLV) is as an early warning signal for treatment failure and onward transmission risk. Uganda has achieved major progress in expanding viral load (VL)...
Analysis of molecular targets and mechanisms of Bisphenol F (BPF)-induced non-alcoholic fatty liver disease (NAFLD) based on network toxicology and molecular dynamics
Bisphenol F (BPF), a primary substitute for bisphenol A (BPA), is widely utilized in industrial production and daily life. However, its widespread environmental presence has raised concerns regarding...
Exploring how entrepreneurship education and entrepreneurial mindset shape students’ entrepreneurial intention in an Iranian university context
Despite the growing emphasis on entrepreneurship education, many university graduates continue to exhibit low entrepreneurial intention and engagement. Understanding how education and entrepreneurial...
Providers of and participants in suicide assistance in Germany: A field description based on expert interviews
Background Over the past 20 years, assisted dying practices have been legalised in an increasing number of countries around the world. After a decision of the German Federal Consti...
First steps towards distinguishing Mediterranean vegetation root marks on bones: An experimental approach
Root-bone interactions are common in buried skeletal remains, yet their diagnostic value remains largely unexplored because few controlled studies have linked root marks to specific plant types. Conse...
Effectiveness and implementation of a primary healthcare intervention for multimorbidity and frailty among urban older adults in India: Protocol for the Multi-FrAME cluster randomized trial
The worldwide impact of multimorbidity and frailty is accelerating among older adults, particularly in India, where healthcare systems face resource constraints. Multimorbidity defined as the coexiste...
PTPRE promotes gastric cancer cell resistance to 5-fluorouracil by inhibiting ferroptosis via the Src/FAK/TRIB3 axis
Acquired drug resistance is a major cause of failure in gastric cancer treatment. The protein tyrosine phosphatase receptor type E (PTPRE) plays an oncogenic role in certain tumours; however, its func...