PLoS ONE
Articles in this Issue
Identifying policy-relevant traffic crash risk factors in Cheongju, South Korea using logistic regression and explainable machine learning
Rapid urbanization and increasing traffic volumes have made the occurrence of traffic crashes and the resulting harm a major public safety concern. This study analyzes traffic crash data from Cheongju...
Test–retest reliability and sensitivity of horizontal jump inter-limb asymmetry in youth soccer players across maturity stages
The present study examined the test–retest reliability and sensitivity of inter-limb asymmetry derived from the single-leg hop test (SLHT) across different maturity stages in young male soccer players...
Non-linear impact mechanisms of multi-modal urban traffic on air quality: An interpretable machine learning study for sustainable policy making
Urban air pollution, specifically Nitrogen Dioxide (NO 2 ), presents a multifaceted challenge that is intricately coupled with the stochastic, multi-modal, and...
Molecular modeling of highly selective CDK1 Inhibitors based on pyrazolo-pyrimidines using 3D-QSAR, docking, and molecular dynamics simulations
Cyclin-dependent kinase 1 (CDK1) has emerged as a compelling target for anticancer drug development due to its essential role in cell cycle regulation. In this study, a series of pyrazolopyrimidine-ba...
Retraction: Digital twin–driven design and testing of laser shock processed aluminum–graphene composites for spacecraft docking tribology
Determine the optimal ignition timing function based on combustion duration, load and fuel blending ratio of an engine powered with diesel-methanol blends
The study employs AVL Boost software to investigate the effects of different methanol blending ratios (BR) in diesel–methanol mixtures (ranging from 0 to 50%), ignition timings (IT), and combustion du...
Chronic kidney disease screening and associated factors among people living with HIV on anti-retroviral therapy in Dar Es Salaam, Tanzania: Hospital-based cross-sectional study
Background Chronic Kidney Disease (CKD) is a significant global health challenge, particularly among people living with HIV (PLHIV) on antiretroviral therapy (ART). The combined ef...
Writing creativity, cohesion, and formal linguistic competence in LLMs: A comparative evaluation based on English and Chinese continuation writing
Recent advancements in large language models (LLMs), such as GPT-3.5, GPT-4, and Chinese models like ERNIE and SparkDesk (SPARK), have shown remarkable potential in story generation. However, a direct...
Pan-genome and reverse vaccinology for a multi-epitope vaccine against circulating post-2022 Monkeypox virus strains
Background Since the 2022 outbreak, the number of Monkeypox cases worldwide has been increasing at an alarming rate. As of August 2024, approximately 99,000 people have been infect...
My avatar moves with me, so I am the one acting: Avatar responsiveness supports implicit sense of agency in virtual reality
Virtual reality (VR) allows users to interact with computer-generated environments in a controlled yet immersive manner. One of its most relevant features is its ability to induce virtual embodiment,...
The occurrence of a particular state is a predictor of successful travel consultation
Dyadic interactions, such as consultations between clerks (i.e., travel agent sales staff) and customers, involve multiple behaviors that reflect people’s internal states, such as interests and prefer...
Hearing loss and executive functions – results from a population-based cohort study
Introduction Hearing loss is linked to cognitive decline, yet its relation to specific executive functions remains unclear. This study examines associations between planning abilit...
Testing for pre- and post-copulatory inbreeding avoidance in the flour beetle Tribolium castaneum
Inbreeding depression poses a significant threat to fitness in many taxonomic groups. Studies have suggested that females may mate with multiple males to reduce inbreeding through post-copulatory disc...
A multi-modal co-attention model for accurate drug-target interaction prediction
Accurate prediction of drug-target interactions (DTIs) plays a crucial role in modern drug discovery and repositioning. Despite recent advances in deep learning, existing methods often fail to effecti...
Extremes on the benign-malignant tumour spectrum: Distinct transcriptomic landscapes between two common canine perianal neoplasms based on the hallmarks of cancer
The hallmarks of cancer describe stepwise changes in cellular functions and molecular pathways of tumour cells that undergo malignant progression. Although 14 hallmarks have been proposed, their manif...
Inhaled nitric oxide in fibrotic and advanced interstitial lung disease: A systematic review and meta-analysis of randomized controlled trials
Purpose Interstitial lung disease (ILD) can lead to pulmonary hypertension (PH), contributing to reduced exercise capacity in patients with ILD. Inhaled nitric oxide (iNO) reduces...
Edible agents with perceptible minds: A psychological study of human perception in human–food interaction
Investigating the psychological and cognitive mechanisms of eating living beings is important for understanding ethical judgments and decision-making in eating behaviors. For example, the meat paradox...
Biomarkers of chronic liver disease and their determinants in northern Ethiopia: Evaluating the synergistic impact of HBV and Schistosoma mansoni and the contribution of metabolic and lifestyle factors to liver injury
Background Liver diseases are a major global health concern, affecting over 1.5 billion people and ranking among the leading causes of death. Sub-Saharan Africa carries a high burd...
Pornography consumption among medical students in Syria: Prevalence, patterns, and predictors
Background Pornography consumption is a global phenomenon, yet empirical research from the Middle East, particularly Syria, is nonexistent. Medical students may be especially vulne...
Association between dynamic digital radiography findings and post-extubation respiratory deterioration: A retrospective exploratory analysis of a prospectively collected ICU cohort
Introduction Dynamic Digital Radiography (DDR) is a novel bedside imaging modality that enables real-time visualization of pulmonary motion with minimal radiation exposure. We eval...
Postoperative renal dysfunction and associated perioperative factors among patients undergoing major vascular surgery at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
Background Postoperative renal dysfunction (PORD) is a common and serious complication following major vascular surgery and is associated with prolonged hospitalization, renal repl...
Retraction: Do Magnetic murmurs guide birds? A directional statistical investigation for influence of Earth’s Magnetic field on bird navigation
Applications of electromyography in Amyotrophic Lateral Sclerosis: A systematic review
This systematic review examined the use of surface electromyography (sEMG) for the neuromuscular assessment of individuals with Amyotrophic Lateral Sclerosis (ALS), focusing on clinical parameters, th...
GL-Net: A knowledge-guided Gaussian-gated and layered refinement network for 3D MRI segmentation of brain gliomas
Glioblastoma is a highly malignant brain tumor, and accurate lesion segmentation in MRI is essential for diagnosis, treatment planning, and prognosis assessment. This paper proposes a knowledge-guided...
Gender discrimination and personal and professional development fostered by allopathic medical schools in the United States
Background Despite prevalent gender discrimination in medical education, its influence on personal and professional development, foundational competencies in medical training per t...