PLoS ONE
Articles in this Issue
Artificial intelligence in the diagnosis of deep vein thrombosis: A scoping review
Deep vein thrombosis (DVT) is the formation of thrombi in the deep venous system, most often in the lower extremities. Although usually not life-threatening, DVT requires timely diagnosis to prevent c...
Correction: Quantum-inspired pedestrian mobility modeling: Applying probabilistic spatial simulation to urban walkability and thermal comfort in Sri Lanka
Emotional demands and burnout: Differential moderating effect of job resources and age
This study, based on the Job Demands–Resources (JD-R) model, investigates how perceived and contact-related emotional demands contribute to burnout, and whether job resources -deep acting, meaning of...
Interpretable machine learning via symbolic classification of radiomic texture and morphological features for pediatric pneumonia detection from chest X-rays
Explainable artificial intelligence in medical imaging is currently dominated by post-hoc tools that rationalise the decisions of otherwise opaque deep networks, without providing, most of the time, a...
Do South Korean adults have insufficient levels of physical activity? Domain patterns and associations with self-rated health
Objectives The study aimed to evaluate domain-specific physical activity (PA) patterns in South Korea, where the prevalence of insufficient PA is high, and assess their association...
Identifying potential inhibitors for wild-type EGFR tyrosine kinase through a cross-talk pathway strategy and an in-silico drug repurposing method
Wild-type epidermal growth factor receptor (EGFRwt) is commonly implicated in tumor growth, yet most of the approved EGFR-targeted therapies are against mutant receptor isoforms, and patients with EGF...
Retraction: SiC ultra -thin films for high-performance quantum spacecraft applications fabricated via nanosecond pulsed laser deposition and doping
Exploration of the associations between muscle oxygen saturation and skin temperature responses during isokinetic strength exercise
Previous studies suggested that skin blood flow, and therefore skin temperature affect changes in muscle oxygenation (SmO 2 ). Given that near-infrared spectros...
Optimization of banana sucker production using different macropropagation structures and substrates
Banana ( Musa spp .) production in Malawi is constrained by limited access to high-quality planting materials, restricting farm productivity. This study evaluat...
Determinants of low birth weight babies delivered at paropakar maternity and Women’s hospital: A case-control study
Background Low birth weight remains a major public health concern due to its association with adverse neonatal, developmental, and long-term health outcomes, with no substantial im...
Outcomes of In-hospital Cardiac Arrest: Insights from a Medical Intensive Care Unit
Background Critically ill patients admitted to intensive care units (ICU) usually suffer from life-threatening illnesses, and many are hemodynamically unstable. The incidence of ca...
AI-assisted thematic synthesis of existing neurological core outcome sets: A descriptive reference framework (COS-Neuro)
Background Neurological disorders affect approximately 3 billion people globally, yet clinical trial success is often hindered by poorly selected outcome measures, impacting trial...
Economic evaluation of the second-line regimen of liposome irinotecan (II) combined with 5-FU/LV versus placebo combined with 5-FU/LV for locally advanced or metastatic pancreatic ductal adenocarcinoma in China
Background The cost-effectiveness of liposome irinotecan (II) (HR070803) in combination with 5-fluorouracil and leucovorin as a treatment for patients with locally advanced or meta...
Correction: Rare event detection by progressive clustering undersampling
Factors associated with resilience among parents of children with autism spectrum disorder: A systematic review
Parents of children with autism spectrum disorder (ASD) experience ongoing caregiving demands and challenges that may contribute to their general well-being. Research has shown that resilience enables...
Effects of incentive spirometer training on dyspnea and functional status in patients with long COVID
Background Since the emergence of Coronavirus Disease 2019 (COVID-19), it has become a global pandemic, profoundly affecting public health and daily life. Many recovering individua...
Dietary supplement consumption among active individuals in Saudi Arabia
Background Despite the increasing use of dietary supplements in Saudi Arabia, accurate information on their consumption patterns and predictors is essential for effective policy pl...
Functional comparison of SP6 RNA polymerase and T7 RNA polymerase
RNA-based therapeutics have emerged as a powerful class of drugs, highlighted by the rapid development and success of COVID-19 vaccines. Therapeutic RNA synthesis relies on in vitr...
Disentangling crossing fibers with advanced dMRI methods reveals bundle-specific degeneration across the visual system in asymmetric glaucoma
Diffusion magnetic resonance imaging (dMRI) is a non-invasive neuroimaging technique that enables in vivo assessment of white matter microstructure and is highl...
Correction: Italy’s progress towards the objectives of the national action plan to combat antimicrobial resistance
Experimental study on mechanical response of soft soil freezing in underground excavation using artificial ground freezing method
To ensure the stability of the artificial frozen wall during the underground excavation of a proposed subway station using the artificial ground freezing method in soft soil strata, and to guarantee t...
Airborne spread of severe acute respiratory syndrome coronavirus 2 between rooms in a sealed, mechanically ventilated ward: Evidence from a hospital outbreak investigation
Airborne transmission of severe acute respiratory syndrome coronavirus 2 in enclosed, mechanically ventilated hospital wards remains poorly characterized. In February 2025, a coronavirus disease clust...
Tumor-associated M2 macrophages promote prostate cancer invasion through the M-CSF-PCLAF pathway
Background Prostate cancer (PCa), particularly in its advanced and castration-resistant forms, remains a major threat to men’s health, with the tumor microenvironment (TME) playing...
Vulnerability assessment to tropical cyclones in the North Caribbean Coast of Nicaragua (1988–2022)
The North Caribbean Coast Autonomous Region of Nicaragua (RACCN) is one of the most vulnerable areas to tropical cyclones (TCs), a condition exacerbated by climate change and internal structural dispa...