PLoS ONE
Articles in this Issue
Downstream community risks post dam-spillage flooding along the Volta River in Ghana: potential pathogens and public health implications
Flooding compromises the microbiological quality of domestic and recreational water sources, increasing exposure to waterborne and opportunistic pathogens in affected communities. Following widespread...
Simulation and performance analysis of a solar-assisted venturi-plasma pasteurization system for milk
This research evaluates the feasibility and performance of a novel solar-powered milk pasteurization system integrating a Venturi tube hydrodynamic reactor and liquid-phase cold plasma technology. Des...
Incidence of Dengue Fever in Pakistan
Introduction Dengue is a growing health threat in Pakistan due to climate, urbanization, and inadequate sanitation. Despite recurrent seasonal outbreaks, comprehensive evidence on...
Short-term effects of alcohol detoxification on cardiovascular, hematological, and oxidative stress biomarkers: A prospective cohort study
Introduction Chronic alcohol consumption induces multisystem dysfunction, including cardiovascular instability, hematological alterations, and oxidative stress imbalance. However,...
A pilot randomized trial on the usability and acceptability of an app (MyIBDDiet) to improve the self-management of anti-inflammatory diet for individuals with inflammatory bowel disease: A protocol paper
The role of diet in the management of inflammatory bowel disease (IBD) is increasingly recognized with recent guidelines providing specific dietary recommendations. Although mobile health apps targeti...
Correction: Potential mechanisms and effects of AFB1-induced asthma: A comprehensive analysis based on network toxicology and molecular docking
Retrospective cohort study of Advanced HIV disease among children and adolescents in Uganda: Characteristics, clinical outcomes, and rate of mortality
Background People diagnosed with advanced HIV disease (AHD) are at high risk for mortality even after starting antiretroviral therapy (ART). We determined characteristics, clinical...
Heart failure hospitalization in patients with and without type 2 diabetes: A population-based retrospective cohort study
Purpose Type 2 diabetes mellitus (T2DM) is a common comorbidity among patients with heart failure (HF). This study aims to describe how T2DM relates to HF hospitalization patterns...
Explainable machine learning for predicting activities of daily living at discharge in stroke patients: A retrospective study using SHAP interpretability
Purpose We aimed to develop a machine learning model to predict activities of daily living (ADL) at discharge in stroke patients and identify key predictors to guide rehabilitation...
Evaluating the impact of the EU Medical Device Regulation (MDR) on mortality and device availability in Germany
Introduction The EU Medical Device Regulation (MDR), effective since May 25, 2017, aims to enhance the safety and quality of medical devices within the EU. This study models the po...
“Shining a light on chronic pain”: A qualitative study of stakeholder views towards chronic pain at work and the Pain-at-Work Toolkit
Purpose The study explored the views of organisational stakeholders who participated in the feasibility trial of the Pain-at-Work Toolkit towards the implementation of the toolkit...
Path loss characterization of a compact dual-band mmWave antenna in urban microenvironments
This work presents a compact dual-band millimeter wave (mmWave) antenna that operates at 17–27 GHz and 36–43 GHz, with resonance frequencies centred at 21.1 GHz and 38.3 GHz, respectively. The multipl...
Retraction: The Succinate Receptor GPR91 Is Involved in Pressure Overload-Induced Ventricular Hypertrophy
Comparative effects of bioelectric and manual toothbrushing on acrylic denture teeth: Surface integrity and wear analysis
Bioelectric toothbrushes deliver a low-level microcurrent intended to disrupt biofilm with reduced mechanical force, yet their effects on denture-tooth wear remain unclear. This in vitro study compare...
Study on the influence of compaction energy and moisture content on the permeability and compression characteristics of granite-weathered soil
The feasibility of reusing granular weathered (GW) soil as foundation fill is closely related to the strength and stability. Initial moisture content and compaction energy were identified as the main...
The role of estimated muscle power from a sit-to-stand test in determining frailty in community-dwelling older adults
Introduction This study explored the usefulness of estimated lower-limb muscle power, derived from the 5-times sit-to-stand (5xSTS) test, for identifying frailty among community-dw...
Hybrid RSM–NSGA-II based multi-objective optimization of electrical discharge machining of AISI D2 steel
In this study, electrical discharge machining (EDM) of AISI D2 die steel was performed by varying three different process parameters: peak current (Ip), pulse-on time (Ton), and duty cycle (c). Enhanc...
Analysis of strength degradation of coal and rock masses and stability of mined areas under long term immersion environment
To address the stability challenges of suspended roof goaf and engineering disasters in coal mine goafs under long-term water immersion, coal rock mass was selected as the research object. Triaxial co...
Association of baseline HBcAg and HBV DNA with persistent detectability of HBV RNA during NA therapy
Objective Even after long-term nucleos(t)ide analogue (NA) therapy achieves hepatitis B virus (HBV) DNA suppression in patients with chronic hepatitis B (CHB), serum HBV RNA may re...
Fascia iliaca compartment block for surgical analgesia in children with osteogenesis imperfecta: A retrospective cohort study
Background Osteogenesis imperfecta (OI) is a rare genetic bone disorder. Children with OI have a higher risk of intraoperative pain. The fascia iliaca compartment block (FICB) can...
Optimising Cold Spray Additive Manufacturing: Pressure-driven enhancement of mechanical performance in copper deposits
Cold spray additive manufacturing (CSAM) is a solid-state process capable of producing dense metallic components without melting, making it highly attractive for copper applications requiring both ele...
Development and qualification of an enzyme-linked immunosorbent assay to detect human serum immunoglobulin G reactive to multiple lineages of Lassa virus nucleoprotein
Lassa fever is a severe, often fatal febrile illness endemic to West Africa caused by Lassa virus (LASV), with different virus lineages predominating across West African countries. The viral nucleopro...
Wetland conversion to farmland in Bure and Womberma Woredas, Northwestern Ethiopia: Implications for sustainable land use
This study investigates the reasons why wetlands transformed to farmland. The data were garnered using Landsat, questionnaire surveys, and key informant interviews. Descriptive statistics were applied...
Assessment of maternal diet inflammatory status and inflammatory markers in human breast milk
Human breast milk is a complex bioactive fluid containing multi-functional components that support many infant physiological functions. Maternal diet has been demonstrated to influence human milk comp...
Spatial distribution of uptake of newly introduced vaccines and its associated factors among children aged 12–35 months in Ethiopia: Multi-scale Geographically Weighted Regression Analysis
Background The pneumococcal conjugate vaccine (PCV) and rotavirus vaccine (RVV) have been introduced to Ethiopia’s expanded childhood immunization program in 2011 and 2013, respect...