PLoS ONE
Articles in this Issue
Muscle strength characteristics and the predictive value of handgrip strength in young obese males: A multi‑joint isokinetic and LASSO regression analysis
Obesity is a primary global public health concern, often associated with impaired muscle function and an increased risk of exercise-related injuries. This cross-sectional study aimed to elucidate the...
Siphonophore genome structure and the evolution of functional specialization
Siphonophores (Cnidaria: Hydrozoa) are pelagic colonial marine invertebrates with many highly specialized bodies (zooids) within a single colony. Their unique biology and ecological importance have ma...
Delayed health-seeking behavior and its associated factors among cancer patients in Ethiopia: A systematic review and meta-analysis, 2025
Background Delayed Health-seeking behavior among cancer patients is a major contributor to late diagnosis, poor prognosis, and high mortality, particularly in low-resource settings...
Emotional understanding in Japanese children 3–6 years: Language ability mediates the relations between theory of mind and executive function
Previous research has documented associations between children’s emotional understanding (EU) and social-cognitive abilities such as theory of mind (ToM) and executive function (EF); however, findings...
A high centrifugal force-enhanced Ziehl–Neelsen method for improved detection of Mycobacterium tuberculosis
Ziehl–Neelsen (ZN) smear microscopy remains central to tuberculosis (TB) diagnosis and treatment monitoring; however, its sensitivity is limited by incomplete recovery of Mycobacte...
Ketogenic diet therapies for the treatment of drug-resistant epilepsy in children and adults: A systematic review
Epilepsy is a common treatable neurological condition characterized by recurrent involuntary brain activity manifested in seizures. It is estimated that around 30% of patients with this disease do not...
The effect of auditors’ digital literacy on reduced audit quality behavior: A chain mediation model and the moderating role of prosocial behavior
Reduced audit quality behavior is prevalent in audit practice and poses a serious threat to overall audit quality. With the increasing adoption of digital auditing, auditors’ digital literacy has beco...
Morpho-biochemical diversity and phytochemical profiling of Rubus fruticosus L. landraces
The flora of Khyber Pakhtunkhwa, Pakistan, is severely threatened by illegal harvesting of non-timber forest resources, resulting in the genetic loss of native plant species, including...
Data-driven prediction and thermodynamic performance assessment of industrial cooling towers using advanced machine learning algorithms
Cooling towers are an important part of the thermal system in industries, where they are used to remove unwanted heat and help maintain the proper performance of the machines. Four machine learning al...
Diabetes among Indigenous Orang Asli adults in Peninsular Malaysia: Prevalence and associated factors from Orang Asli Health Survey 2022
Background Type 2 diabetes mellitus (T2DM) is a growing public health problem globally, and in Malaysia. Orang Asli, the Indigenous population in Peninsular Malaysia, often experie...
Navigating ethical waters: The impact of ethical judgment, norms, and CSR skepticism on CSR engagement and purchasing intention in a breast cancer campaign
Corporate social responsibility (CSR) campaigns play a crucial role in shaping consumer perceptions and behavior. This study examines Delta Air Lines’ CSR campaign centered on breast cancer awareness,...
Preparation and physicochemical characterization of a biodegradable chitosan/carboxymethyl cellulose hydrogel synthesized in NaOH/urea medium
The use of super absorbent polymers in agriculture for water and fertilizers retention in soils has become popular with the increasing need for resource optimization. The objective of the present stud...
The uncertain self: Intolerance of uncertainty moderates the association of both positive and disorganized schizotypal traits with self-concept clarity in a non-clinical sample
Our objective was to investigate the relationship between self-concept clarity, intolerance of uncertainty, and schizotypal traits, with a focus on whether intolerance of uncertainty moderates the ass...
Health impacts of climate change on children and adolescents: A protocol for review of reviews
Introduction Climate change is a contemporary phenomenon of grave concern to global public health. Climate change events such as droughts, wildfires, tornadoes, heatwaves, floods,...
Seasonal patterns of vegetation drought resilience and vegetation loss in Central Asia
Drought events have become increasingly common in Central Asia, increasing the risk of vegetation degradation. In this study, the resilience of vegetation to drought and its drivers was investigated a...
Association of oral health knowledge, attitudes, and practice with dental caries status among 6–12-year-old Iranian orphaned children using the CAST index: A Cross-sectional study
Introduction Orphaned children face heightened vulnerability due to the absence of parental care and limited access to preventive services. Evidence linking oral health knowledge,...
Research on the impact of artificial intelligence on the export technological complexity of chinese manufacturing enterprises: An analysis based on mediating effects
Technological innovation drives high-quality economic development, and artificial intelligence (AI) represents a new impetus for developing productive forces with new qualities. AI is becoming a focal...
Age, gender, and score distributions of moral foundations
Claims of generational differences in moral values have important implications for understanding societal change. Using the recently developed Moral Foundations Questionnaire (MFQ-2), we examined age...
Perceptions of research participation among underrepresented groups: Insights using freelisting methodology
Background Low enrollment and retention in clinical research disproportionately impact Black, Hispanic or Latinx, women, and rural populations, undermining generalizability and per...
Nine keys for successful interprofessional collaboration Based on observing facilitators and barriers during different types of treatment meetings: A qualitative study
Introduction The increasing prevalence of multimorbidity requires effective collaboration between health professionals. Both interprofessional (IP) and multidisciplinary (MD) colla...
An exercise-associated gut microbiota signature enhances endurance performance: A study combining a human cohort and a mice FMT model
Background The gut microbiota is closely related to exercise, but the interrelationship between the two remains elusive. In this study, we aimed to explore differences in the gut m...
Development of a blended MOOC implementation model for English language learning: An interpretive structural modeling approach
The integration of Massive Open Online Courses (MOOCs) into traditional English language education has created new opportunities for scalable, flexible, and inclusive learning. However, existing studi...
A network pharmacology-based approach and molecular docking study to explore the therapeutic potential of a nutraceutical formula (Vernolac) in the treatment of cancer
Vernolac is a commercially available polyherbal nutraceutical capsule containing Vernonia zeylanica aerial parts, Nigella sativa...
Determining optimal practices for foal weaning – A protocol for a systematic review and network meta-analysis
Background Weaning is a stressful time in a foal’s ( Equus caballus ) life. As humans artificially manage weaning...
Short- and long-term scaling behavior of blood pressure and pulse arrival time during sleep in healthy controls and patients with obstructive sleep apnea
Obstructive sleep apnea (OSA) is characterized by recurrent respiratory events that trigger autonomic arousals and blood pressure (BP) surges, contributing to elevated cardiovascular risk. Photoplethy...