PLoS ONE
Articles in this Issue
Green spot in ‘WA 38’: Growth dynamics, vascular integrity and architecture, and a hypothetical mechanism
‘WA 38’ is a cross of ‘Enterprise’ and ‘Honeycrisp’. It is susceptible to the surface disorder known as green spot (GS), which reduces its marketability. This study aimed to characterize fruit growth...
Utilization of cell-penetrating peptide adaptors to enhance delivery of variably charged protein cargos
Cell-penetrating peptides (CPPs) can deliver biomacromolecular cargos into cells, potentially enabling a new mode of intracellular drug delivery. However, a major problem with CPP-mediated delivery is...
Real-world evidence of physical activity practices and policies in Greater London primary schools: A cross-sectional survey
Background The World Health Organization (WHO) recommends six domains for a whole-school approach to promote physical activity (PA) levels. This approach aims to help children achi...
Examining relationship between unhealthy lifestyle and life satisfaction among new students at Tehran University of Medical Sciences
Background Transitioning to university is a critical period marked by lifestyle changes, academic pressures, and increasing autonomy, which can influence students’ overall well-bei...
Corrosion assessment in aluminum pipe based on nonlinear ultrasonic technique using macro fiber composite transducers
Pipe corrosion, specifically pitting corrosion, is the main cause of destructive pipe leakage, driven by the harsh working environment of liquid and gas transportation. Therefore, detecting pitting co...
Editorial Note: Study on optimization of inspection mechanism of concrete beam bridge
miR-132 overexpression is associated with modulation in miR-21 expression and glioblastoma cell behavior
Glioblastoma multiforme (GBM) is the most aggressive and lethal primary tumor of the central nervous system. MicroRNAs (miRNAs) are key post transcriptional regulators of gene expression, and increasi...
Prevalence and risk factors of hypertension in rural Bangladesh: A population-based cross-sectional study
Non-communicable diseases (NCDs), such as hypertension, are amongst the most fatal conditions afflicting people living in low- and middle-income countries (LMIC), including Bangladesh. This study addr...
NLOS/LOS identification with LightGBM ensemble
Non-Line-of-Sight (NLOS)/Line-of-Sight (LOS) identification is crucial to accurate Ultra-Wideband (UWB) positioning. The current Machine Learning solutions to this problem have either too many paramet...
Intuitionistic fuzzy PAMSSEM method for MAGDM incorporating cumulative prospect theory and its application to the assessment on water resource carrying capacity
Assessing water resources carrying capacity (WRCC) is essential for regional high-quality development. However, most existing WRCC assessment models fail to handle uncertainties and mixed data arising...
Editorial Note: Heat health risk assessment analysing heatstroke patients in Fukuoka City, Japan
Burnout in primary healthcare providers: A cross-sectional study from Al-Khobar, Saudi Arabia
Aim Job burnout is one of the emerging challenges in the healthcare sector which caused various issues among the primary healthcare providers. Hence, the present study was designed...
GraphTransDTI: A novel hybrid framework combining graph transformer and CNN-BiLSTM for enhanced Drug-Protein Interaction prediction
Drug-protein interaction (DTI) prediction is a pivotal step in the drug discovery and repurposing process, helping to minimize experimental costs and time. However, existing deep learning methods ofte...
Sexual harassment at work: Targets’ perspectives on prevention and response
Harassment, including sexual harassment, in the workplace poses a significant threat to workers’ wellbeing and contributes to social inequities. Organizations play a pivotal role in both enabling and...
Adaptive geometric-attention network for two-stage lung nodule segmentation and malignancy classification in federated healthcare IoT edge environments
Accurate segmentation and classification of lung nodules in computed tomography (CT) scans remains a critical challenge in early lung cancer detection within distributed healthcare Internet of Things...
Simulation of emulsion evolution in shear flow field under the control of bidirectional pulsed electric field
Electrostatic demulsification is a widely used technique for treating high-water-cut emulsions (O/W type). However, in high-water-cut emulsions, continuous electric fields often lead to short-circuiti...
Tear-film imaging measurements of the lipid and muco-aqueous layers and their association with dry eye disease signs and symptoms in adults: A pilot, prospective, cross-sectional study at a tertiary eye care center
The purpose of this study was to assess tear film (TF) parameters in subjects with signs and symptoms of dry eye disease (DED) using a novel nanometer resolution tear film imager (TFI, AdOM, Israel)....
Comparative analysis of the mucosal and shell microbiota of Trachemys scripta elegans across multiple urban freshwater habitats
Turtles harbor diverse microbial communities that influence their health, ecology, and interactions with the environment. While sea turtle microbiomes have received growing attention, the microbial co...
Evaluating the feasibility and acceptability of home-based isometric exercise and behaviour change for the management of hypertension: The HOME-FIT study protocol
This protocol describes a pilot randomised controlled trial that aims to assess the feasibility and acceptability of a 24-week remotely delivered home-based isometric exercise and behaviour change int...
Psychological distress in hypertension: Prevalence and links to self-care in Gonabad, Iran
Introduction A critical component in the hypertension management and the prevention of its life-threatening complications, is self-care. Psychological factors such as stress, anxie...
Measuring airway compliance of pulmonary fibrosis by endobronchial optical coherence elastography
Background Optical coherence elastography derived from optical coherence tomography for measuring soft tissue and organ compliance, holds promise in respirology but remains largely...
In the belly of the beast: How dietary changes and preexisting invasive prey may have promoted the success of a novel invasive amphibian
Biological invasions provide unique opportunities to examine how populations cope with rapid ecological change, as well as the influence of human activity on our natural world. The island of Newfoundl...
Phytochemical and biological evaluation of methanolic extracts as a preventive measure for antioxidant and Anticoccidial Eimeria columbae Oocysts
Background Herbal products are rich in the source of bioactive ingredients, including phenols, flavonoids, tannins, and essential oil components such as cinnamaldehyde, eugenol, an...
Editorial Note: Response of vegetation to submergence along Jingjiang Reach of the Yangtze River
Can dietary supplementation with highly purified fucoidan alter growth, digestive enzyme activity, serum biochemicals, immune-antioxidant responses, and related gene expressions in Nile tilapia (Oreochromis niloticus)?
The present study investigates the impact of dietary fucoidan supplementation on growth performance, intestinal tract morphology, endogenous digestive enzymes, hematological parameters, serum biochemi...