PLoS ONE
Articles in this Issue
Effect of drainage layers on water retention of potting media in containers
Excess water retention in the potting medium can be a significant problem for plants grown in containers due to the volume of saturated medium which forms above the drainage hole. Adding a layer of co...
Impact of β-defensin 103 (DEFB103) copy number variation on bull sperm parameters and post-insemination uterine gene expression
Pregnancy rates for elite bulls used in artificial insemination (AI) can vary significantly and therefore the identification of molecular markers for fertility and targets to improve bull selection is...
Fetal genetic factors in pregnancy loss: Insights from a meta-analysis and effectiveness of whole exome sequencing
Spontaneous pregnancy loss commonly occurs during the first trimester and can be caused by various factors including chromosomal abnormalities and submicroscopic aberrations. After the first trimester...
Evaluation of psychiatric conditions in asymptomatic outpatient clinic patients
Introduction A significant part of the internal medicine outpatient clinic burden consists of patients who are asymptomatic and intend to have routine check-up tests. In this study, we aimed to invest...
Effects of pressure on the survival and viability of cancer cells in vitro: An analytical study
Intense cancer research is underway to discover possible therapies but no major breakthrough appears to be in sight in terms of its cure when diagnosed late. The cytostatic and growth inhibitory effec...
Astragalus polyphenols attenuates doxorubicin-induced cardiotoxicity by activating the PI3K/AKT/NRF2 pathway
Background Doxorubicin (DOX) is a powerful chemotherapeutic agent commonly employed in cancer treatment. However, its clinical utility is constrained by dose-dependent cardiotoxicity, which can result...
Influence of new qualitative productivity forces on quality-effective change in China’s Yangtze river economic belt sports industry: The mediating effect of industry–University–Research Cooperation
Due to the lack of empirical research on the influence of new qualitative productivity forces on quality-effective change in the sports industry, entropy-weighted threshold-based estimation (TOPSIS) i...
Consumption of protect and risk food groups for non-communicable diseases among women of reproductive age in rural areas of Morogoro, Tanzania
Malnutrition has been persistently high in Tanzania, especially in the rural areas. Although some interventions have been implemented to reduce the rate of undernutrition, improvement is much slower t...
RETRACTED: Enhancing the decision optimization of interaction design in sustainable healthcare with improved artificial bee colony algorithm and generative artificial intelligence
With the development of digital health, enhancing decision-making effectiveness has become a critical task. This study proposes an improved Artificial Bee Colony (ABC) algorithm aimed at optimizing de...
Machine learning for predicting antimicrobial resistance in critical and high-priority pathogens: A systematic review considering antimicrobial susceptibility tests in real-world healthcare settings
Background Antimicrobial resistance (AMR) poses a worldwide health threat; quick and accurate identification of AMR enhances patient outcomes and reduces inappropriate antibiotic usage. The objective...
Evaluating refrigeration and antibiotic treatment for maintaining urine electrophysiology
Background Electrophysiological analysis of urine has shown utility in differentiating between healthy and bladder cancer specimens, offering a rapid, label-free alternative to molecular methods. Howe...
Soluble RAGE enhances muscle regeneration after cryoinjury in aged and diseased mice
The Receptor for Advanced Glycation End Products (RAGE), classically considered a mediator of acute and chronic inflammatory responses, has recently been implicated by genetic knockout studies as a re...
The 24-hour movement behaviour compositions of children with and without impaired motor coordination: The Moves-UP project
The 24-hour movement behaviours, including sleep, sedentary behaviour (SB), and moderate-to-vigorous physical activity (MVPA) are crucial for a child’s healthy growth and development. Yet, the full 24...
Weaving a new web: gregarious parasitism in Idris Förster (Hymenoptera: Scelionidae) attacking spider eggs
The present study, conducted in West Bengal, India, explored the unique ‘multi-chambered’ appearance of certain spider eggs, leading to the discovery of gregarious parasitism in the idiobiont endopara...
Capsicum chinense Jacq. fruit plays an immunomodulatory role in cytokine attenuation and DNA damage protection
Capsicum chinense (C. chinense) Jacq., recognized for its bioactive compounds, has attracted interest due to its possible immunomodulatory and DNA-damage-protective effects. This study aimed to assess...
Implications of tissue specific STING protein flux and abundance on inflammation and the development of targeted therapeutics
Drugs targeting the ER-resident innate immune receptor Stimulator of Interferon Genes (STING) are in development for treatments of cancer and inflammatory diseases. Accurate determination of STING rec...
Couple-centered HIV prevention and care: Endorsement, practice and uncertainty among us healthcare providers in western-central upstate New York
Given the influence of provider perspective and practice in the uptake of HIV/STI prevention and care strategies, this qualitative descriptive design study sought to illuminate perspectives of couples...
The role of renal and liver function in clinical ctDNA testing
Circulating tumor DNA (ctDNA) has high clinical potential in early cancer detection. The renal system and the liver are involved in clearing circulating cell free DNA (cfDNA) from the blood. Recent st...
Association between cardiometabolic index and albuminuria: Evidence from NHANES 2017–2020
Introduction Albuminuria is a crucial marker of kidney damage and serves as an early indicator of the risk for chronic kidney disease (CKD). Recent studies have suggested that the cardiometabolic inde...
Fusion of motion smoothing algorithm and motion segmentation algorithm for human animation generation
In the field of human animation generation, the existing technology is often limited by the dependence on large-scale data sets, and it is difficult to capture subtle dynamic changes when processing m...
Policy-mix and SME innovation: Evidence from China
The question of whether and how innovation policy can effectively influence innovation in small and medium-sized enterprises (SMEs) has received limited attention in academic research. This study take...
Poor sleep patterns are associated with the prevalence of benign prostatic hyperplasia in US aged 40 and older: A cross-sectional study based on NHANES
Background The connection between sleep patterns (sleep duration, trouble sleeping and sleep disorders) and benign prostatic hyperplasia, commonly referred to as BPH, is not yet clear. Our aim is to i...
Responses of soil labile organic carbon stocks and the carbon pool management index to different vegetation restoration types in the Danxia landform region of southwest China
Soil organic carbon (SOC) is an important index for evaluating soil quality in the process of ecological restoration. It plays an important role in increasing soil carbon storage, improving soil textu...
Measurement accuracy and cutoffs for predicting primary aldosteronism diagnosis using Lumipulse® for renin and aldosterone measurements
Objectives Primary aldosteronism (PA) diagnosis is a multistep process that begins with screening based on the plasma aldosterone-to-renin ratio (ARR). As cut-off values depend on the methods used, t...
Wastewater surveillance overcomes socio-economic limitations of laboratory-based surveillance when monitoring disease transmission: The South African experience during the COVID-19 pandemic
Wastewater and environmental surveillance has been promoted as a communicable disease surveillance tool because it overcomes inherent biases in laboratory-based communicable disease surveillance. Yet,...