PLoS ONE
Articles in this Issue
FORCETRACKER: A versatile tool for standardized assessment of tissue contractile properties in 3D Heart-on-Chip platforms
Engineered heart tissues (EHTs) have shown great potential in recapitulating tissue organization, functions, and cell-cell interactions of the human heart in vitro. Currently, multiple EHT platforms a...
TWINKLE: An open-source two-photon microscope for teaching and research
Many laboratories use two-photon microscopy through commercial suppliers, or homemade designs of considerable complexity. The integrated nature of these systems complicates customization, troubleshoot...
Table tennis coaching system based on a multimodal large language model with a table tennis knowledge base
Table tennis is one of the most popular sports in the world, and it plays a positive role in the overall development of people’s physical and mental health. This study develops an AI table tennis coac...
Integrating transcriptome and metabolomics revealed the key metabolic pathway response of Amaranthus retroflexus L. to the resistance to fomesafen
Background Amaranthus retroflexus L. is one of the main broad-leaved weeds in soybean fields in Heilongjiang Province and is an important factor affecting soybean yield. It is becoming increasingly re...
Optimizing in-store warehouse safety: A DEMATEL approach to comprehensive risk assessment
Introduction In-store warehouses can be a dangerous place due to the storage of a high volume of diverse life goods which may raise the total risk of warehouse. The turnover of goods in this kind of w...
How regional innovation and entrepreneurship vitality affects residents’ leisure consumption potential—utility differences between educational investment and scientific and technological investment
Innovation and entrepreneurship vitality, as a key factors in the development of the digital economy, significantly affects both regional economic development and residents’ consumption capacity. On t...
Effects of Taekwondo intervention on balance ability: A meta-analysis and systematic review
Objective This study investigated the effects of Taekwondo interventions on balance ability through meta-analysis and systematic review. Additionally, an optimal intervention protocol was proposed bas...
LIPG-mediated regulation of lipid deposition and proliferation in goat intramuscular preadipocytes involves the PPARα signaling pathway
Endothelial lipase (LIPG), a member of the triglyceride lipase family, plays an essential role in human diseases and lipid metabolism. However, its function in goat intramuscular fat (IMF) deposition...
ILR-Net: Low-light image enhancement network based on the combination of iterative learning mechanism and Retinex theory
Images captured in nighttime or low-light environments are often affected by external factors such as noise and lighting. Aiming at the existing image enhancement algorithms tend to overly focus on in...
Digital mental health service engagement changes during Covid-19 in children and young people across the UK: Presenting concerns, service activity, and access by gender, ethnicity, and deprivation
The adoption of digital health technologies accelerated during Covid-19, with concerns over the equity of access due to digital exclusion. The aim of this study was to assess whether service access an...
The importance of genetic counselling and testing in inherited eye diseases: A population-based retrospective study
Purpose Inherited eye diseases (IEDs) are among the main causes of visual impairment and blindness in children and young people worldwide. The objective of our study was to characterize the prevalenc...
Digital transformation and liquidity creation in commercial banks: Evidence from the Chinese banking industry
This study investigates the impact of digital transformation on the liquidity creation among banks in China, focusing on 127 commercial banks from 2010 to 2021. The research is driven by the observed...
Managing flash flood crises with cultural perspectives: A user-centric feature identification study
Flash floods are severe disaster that have caused enormous damage to people, property, and the environment. Despite the conventional emphasis on technical and engineering solutions in controlling flas...
Production risk and technical efficiency of dry-season vegetable farmers in the Upper East Region of Ghana
The Ghanaian population is aware of the increasing health challenges in our health facilities and the need to consume more vegetables to improve their health status. This, coupled with population grow...
Factors associated with pulmonary tuberculosis in elderly individuals: A protocol for a scoping review
Background Tuberculosis (TB) is an infectious disease with a significant impact on public health, with the pulmonary form being the most critical. The disease poses numerous risks to the elderly popul...
The effectiveness and safety of physical activity and exercise on women with endometriosis: A systematic review and meta-analysis
Background Endometriosis is a debilitating, chronic disease that affects approximately 10% of women of reproductive age worldwide. The most common symptom is chronic pelvic pain, which leads to a redu...
Exploring the combined effect of optimally controlled chemo-stem cell therapy on a fractional-order cancer model
This study aims to investigate the effect of fractional order on a novel cancer treatment model in the Caputo sense with chemotherapy and stem cell therapy. The existence of positive solutions, equili...
Exploring the effects of quercetin-added pancreatic diet on metabolic homeostasis in dogs via metabolomics
Objective To investigate the role of quercetin-added pancreatic prescription food in regulating metabolic homeostasis in dogs. Methods The experimental dogs were divided into a control diet group...
Multi-step depth enhancement refine network with multi-view stereo
This paper introduces an innovative multi-view stereo matching network—the Multi-Step Depth Enhancement Refine Network (MSDER-MVS), aimed at improving the accuracy and computational efficiency of high...
Underwater target depth estimation: A shallow-water broadband acoustic source depth estimation method based on corrected warping transformation
A broadband sound source depth estimation method based on the BDRM model is proposed for the shallow sea to address the problem that the traditional Warping transform is limited by the ideal waveguide...
Global prevalence of elevated estimated pulmonary artery systolic pressure in clinically stable children and adults with sickle cell disease: A systematic review and meta-analysis
Background The current study sought to determine the prevalence of elevated estimated pulmonary artery systolic pressure (ePASP) in clinically stable children and adults with sickle cell disease)SCD(w...
Passive acoustic monitoring of baleen whale seasonal presence across the New York Bight
The New York Bight is an ecologically and economically important marine region along the U.S. Atlantic Coast. Extensive assessments have characterized the habitats and biota in this ecosystem; however...
Financial cost of assisted reproductive technology for patients in high-income countries: A systematic review protocol
Background Infertility affects one in six people globally, with similar prevalence rates across high-income and low- and middle-income countries. Technological advancements, particularly in Assisted R...
Effect of Chinese herbal medicine (CHM) as an adjunctive therapy in distinct stages of patients with COVID-19: A systematic review and meta-analysis
Background The pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of infected cases and deaths worldwide. Clini...
Cost-sensitive multi-kernel ELM based on reduced expectation kernel auto-encoder
ELM (Extreme learning machine) has drawn great attention due its high training speed and outstanding generalization performance. To solve the problem that the long training time of kernel ELM auto-enc...