PLoS ONE
Articles in this Issue
Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways
Crateva religiosa, a plant used in traditional medicine, is valued for its bioactive properties. Traditional approaches are more accepted worldwide as a cost effective alternatives being used in netwo...
PCYT2 overexpression induces mitochondrial damage and promotes apoptosis in hepatocellular carcinoma cells
Phosphatidylethanolamine cytidyltransferase 2 (PCYT2) is commonly regarded as the rate-limiting enzyme in eukaryotic phosphatidylethanolamine synthesis. However, the role of PCYT2 in the development o...
Does host-guest interaction promote tolerance behavior? The mediating role of place attachment and subjective well-being
This study explores the mediating role of place attachment (PA) and subjective well-being (SWB) in the mechanism of tourist tolerance behavior (TTB) from the perspective of host-guest interaction (HGI...
Rethinking vegetarianism: Differences between vegetarians and non-vegetarians in the endorsement of basic human values
Differences between the basic human values of vegetarians and non-vegetarians were examined in three studies of samples of adults drawn from general populations, one in the US and two in Poland. Veget...
Roles of logistics service quality in shaping generation Z customers’ repurchase intention and electronic word of mouth in E-commerce industry
As e-commerce continues to reshape retail landscapes, logistics service quality (LSQ) has become a crucial determinant of customer trust, satisfaction, and long-term engagement. This study investigate...
Exploring green purchasing intentions and behaviours among Vietnamese Generation Z: A perspective from the theory of planned behaviour
As environmental degradation escalates, the critical need to understand green purchasing intentions and behaviours among Vietnamese Generation Z becomes increasingly urgent. Although the Theory of Pla...
Can splitting influence corporate strategy? Exploring the effects of TMT faultlines on internationalization speed
On the basis of upper echelons theory, this paper examines the effect of TMT faultlines on internationalization speed and considers the contextual factors that may affect the focal relationship. We fo...
A scoping review and quality assessment of machine learning techniques in identifying maternal risk factors during the peripartum phase for adverse child development
Maternal exposure to environmental risk factors (e.g., heavy metal exposure) or mental health problems during the peripartum phase has been shown to lead to negative and lasting impacts on child devel...
Epimedin C enhances mitochondrial energy supply by regulating the interaction between MIC25 and UBC in rodent model
The study investigates the molecular mechanisms underlying the skeletal muscle-enhancing effects of Epimedin C, a natural flavonoid, focusing on its interaction with the mitochondrial cristae structur...
Impacts of climate change on the distribution pattern of Himalayan Rhubarb (Rheum australe D. Don) in Nepal Himalaya
While there has been substantial consensus that climate change poses a severe threat to the Himalayan biota; we still lack comprehensive data on the potential impact of climate change on the important...
Topic modeling and evolutionary trends of China’s language policy: A LDA-ARIMA approach
Background Language policy serves as an essential tool for governments to guide and regulate language development. However, China’s current language policy faces challenges like outdated analytical me...
The association of sarcopenia, possible sarcopenia and cognitive impairment: A systematic review and meta-analysis
Objectives The study aimed to investigate the relationship between sarcopenia, possible sarcopenia, and cognitive impairment, and to analyze the impact of potential moderating factors. Methods A com...
Association between androgen receptor gene and behavioral traits in cats (Felis catus)
Cats (Felis catus) are companions familiar to people worldwide. Despite their popularity, few studies have investigated the genetic background of their behavior. This study aimed to explore the relati...
Downward accountability mechanism effectiveness by non-governmental organizations in low- and middle-income countries: A qualitative systematic review
Background Downward accountability, defined as being answerable to beneficiaries for actions and giving affected populations influence in aid processes, remains unstandardized and underinvested across...
Analysis of the efficacy of splenic artery superselective embolization in cirrhosis with hepatocellular carcinoma
Background To explore the safety and effectiveness of partial splenic embolization (PSE) in patients with hypersplenism and hepatocellular carcinoma (HCC) and to compare the efficacy of superselective...
Sleep behaviors and metabolic-associated fatty liver disease
Objective This study aimed to comprehensively evaluate the association between various sleep behaviors and the risk of metabolic-associated fatty liver disease (MAFLD), particularly self-reported snor...
Resolution of the High versus Low debate for Old and Middle Kingdom Egypt
The unrivaled millennia-long historical chronology of ancient Egypt forms the backbone for archaeological synchronization across the entire Eastern Mediterranean region c. 3000-1000 BCE. However, for...
Effects of chemical exposures and diet on birth outcomes in a New York City pregnancy cohort: Mediation through favorable fetal growth conditions
Background Fetal growth is shaped by a complex interplay of parental traits, environmental exposures, nutritional intake, and genetic predispositions. In epidemiological research, birth weight is wide...
The changing impact of the active job openings-to-applicants ratio (AJOAR) on ambulance dispatches during deflation: A longitudinal ecological study
Background Frequent ambulance dispatches is a common challenge in developed countries. Several factors have been identified as contributing to increase in dispatches, but no stipulation has explained...
Association between virtual visits and health outcomes of people living with HIV: A cross-sectional study
Background Virtual care has been integrated as a modality of care in Ontario, yet its effectiveness for people living with HIV remains largely unexplored....
Retraction: A novel triple repeat mutant tau transgenic model that mimics aspects of pick’s disease and fronto-temporal tauopathies
Rural labor migration and household waste separation willingness: Evidence from 6849 rural residents in China
Understanding the key determinants of rural household waste separation willingness (HWSW) is indispensable in promoting sustainable development for many developing economies. Few studies have been ded...
The impact of mergers and acquisitions on technological innovation in state-owned enterprises: The moderating role of mixed-ownership
Using data from Chinese A-share listed state-owned enterprises (SOEs) between 2007 and 2019, we examine how mergers and acquisitions (M&As) affect SOE innovation through patent outputs, with a foc...
Facilitators, barriers, and strategies for the implementation of peer-led tuberculosis active case finding among people who use drugs in Dar es Salaam, Tanzania
Background Globally, tuberculosis (TB) is the leading cause of death from a single infectious agent. In 2023, an estimated 2.7 million cases of TB were undiagnosed or unreported. To address missing ca...
Integration of bioinformatics and identification of the role of m6A genes in NAFLD
Non-alcoholic fatty liver disease (NAFLD) is prevalent worldwide and seriously affects health. M6A methylation is crucial in its pathogenesis. In this study, a thorough analysis of three gene expressi...