PLoS ONE
Articles in this Issue
Economic impact of the Elecsys anti-Müllerian hormone Plus immunoassay for anti-Müllerian hormone testing as part of polycystic ovary syndrome assessment in the United Kingdom
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women. Current international PCOS assessment and management guidelines recommend anti-Müllerian hormone (AMH) as an alterna...
Research on the correlation between retinal vascular parameters and axial length in children using an AI-based fundus image analysis system
Objective This study aims to utilize artificial intelligence technology to conduct an in-depth analysis of fundus data from myopic children and adolescents, thoroughly exploring the correlation betwee...
Arrhythmia classification based on multi-input convolutional neural network with attention mechanism
Arrhythmia is a prevalent cardiac disorder that can lead to severe complications such as stroke and cardiac arrest. While deep learning has advanced automated ECG analysis, challenges remain in accura...
Space-time analysis of head and neck cancer in Asia and its 34 countries and territories (1990–2021): Implications from the Global Burden of Disease Study 2021
Background Asia bears a disproportionate burden of head and neck cancer (HNC). This study aimed to analyze its spatial distribution and temporal trends in Asia from 1990 to 2021, projecting trends to...
The state value
This paper considers the state value using the future contract pricing approach. Our model allows adding an unlimited number of factors that affect the state value. We think this model may be useful t...
Evaluation of optimal strategies for breast cancer screening in Ghana: A simulation study based on a continuous tumor growth model
Mammographic breast cancer screening plays a crucial role in detecting small tumors, which can prevent the progression of the disease and reduce the risk of breast cancer mortality. This study aimed t...
EPHX1 and ERCC2 polymorphisms are associated with cisplatin-induced nephrotoxicity and prognosis in Thai cancer patients
Cisplatin is a widely used chemotherapeutic drug for various cancers. One of the common adverse effects of cisplatin is nephrotoxicity including acute kidney injury (AKI) and acute kidney disease (AKD...
Characterization and prediction of non-melanoma skin cancer incidence in China: Joinpoint regression and age-period-cohort model
Objective Understanding the non-melanoma skin cancer (NMSC) incidence and its trends in China is an important prerequisite for effective prevention and control of NMSC. Methods NMSC incidence data w...
A hybrid approach to enhance HbA1c prediction accuracy while minimizing the number of associated predictors: A case-control study in Saudi Arabia
Type 2 diabetes (T2D) is considered a significant global health concern. Hemoglobin A1c level (HbA1c) is recognized as the most reliable indicator for its diagnosis. Genetic, family, environmental, an...
Global genetic diversity of Infectious Salmon Anemia Virus (ISAV) a scoping review protocol
Background Infectious salmon anemia virus is one of the most important pathogens responsible for causing infectious salmon anemia in Atlantic salmon (Salmo salar). Following its first emergence in 198...
Thermal stress and thermal deformation of a nozzle flowmeter with different weld structures
Nozzle flow meters are widely used in the field of measuring high temperature media. In order to investigate the effect of nozzle flowmeter weld structure on thermal stress and thermal deformation, 10...
Inter-agency collaboration to support the COVID-19 response and maintain malaria services in Guinea and Sierra Leone: A social network analysis
Inter-agency networks are believed to be essential to maintaining essential health services during pandemics and to strengthening the resilience of health systems. Focusing on malaria during the COVID...
Preventing respiratory illness in cerebral palsy: Results of a pilot randomized controlled trial
Background Respiratory illness is consistently the leading cause of death and hospitalization in severe cerebral palsy (CP). Respiratory Exacerbations-Plan for Action and Care Transitions (RE-PACT) is...
Physicochemical quality assessment of four asparaginases
L-Asparaginases (ASNases) are used for the treatment of acute lymphoblastic leukaemia. There are reports of quality problems for some therapeutic asparaginase products, especially those manufactured i...
Genome-wide molecular fingerprinting reveals local geographical genetic patterns in the North American angiosperm genus Triosteum (Caprifoliaceae)
Triosteum (Caprifoliaceae) is a genus of herbaceous perennial angiosperms composed of three Asian and three North American species. The range of two similar species, T. aurantiacum and T. perfoliatum,...
Vertical distribution characteristics and source apportionment of nitrogen in the Longyangxia Reservoir in the upper reaches of the Yellow River
Studying the biogeochemical cycle of biogenic nitrogen and its influence on hydrological processes and anthropogenic nitrogen input is of great significance for water resource management and the maint...
Integrative review in PhD admissions: A case study of efficiently minimizing bias while maximizing the student narrative
Developing scientific and medical innovations continue to be limited by lack of diverse representation among leaders and learners. One key gateway for these goals is graduate school admissions, but co...
Investigation of nanotexture fabrication by magnetic field assisted ultra-precision diamond cutting
Ultra-precision machining (UPM) is crucial for producing parts with functional surfaces featuring nano textures, yet it faces challenges in generating such textures. This paper explores the potential...
Lived experiences and coping strategies of people living with Glaucoma in Nigeria: A qualitative study
Background The diagnosis of visual impairments and other chronic diseases is associated with frustration, anxiety and depression emanating from potential functional limitations, social restrictions, e...
Antimicrobial resistance and molecular detection of extended-spectrum ß-lactamase (ESBL)-producing Escherichia coli in municipal wastewater in Marrakech
Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) poses a major threat to public health. However, its environmental dissemination, especially through wastewater, remains insufficientl...
Retraction: Ribosome-Dependent ATPase Interacts with Conserved Membrane Protein in Escherichia coli to Modulate Protein Synthesis and Oxidative Phosphorylation
A machine learning based authentication and intrusion detection scheme for IoT users anonymity preservation in fog environment
Authentication is a critical challenge in fog computing security, especially as fog servers provide services to many IoT users. The conventional authentication process often requires disclosing sensit...
Interventions supporting the translation of gerontological evidence into practice to optimize functional outcomes for hospitalized older adults: A scoping review
Background and objectives Hospitalized older adults are at risk for both physical and cognitive functional decline. To support the implementation of interventions optimizing their function, both healt...
Rapid determination of sodium pentachlorophenate in bamboo and wooden cutting boards via ultrasonic-assisted liquid-liquid extraction coupled with ultra-performance liquid chromatography-high resolution mass spectrometry
Sodium pentachlorophenate (PCP-Na) is a toxic preservative used in wood products, posing potential health risks through food contact materials. A rapid analytical method combining ultrasonic-assisted...