PLoS ONE
Articles in this Issue
Study on the quantitative analysis of Tilianin based on Raman spectroscopy combined with deep learning
Tilianin is a commonly used pharmaceutical ingredient with various biological activities such as antioxidant, anti-inflammatory, and anticancer, which is able to exert antitumor effects by inhibiting...
Circular saw blade wear status prediction based on generative adversarial network and CNN-LSTM model
Monitoring the status of circular saw blades is an effective measure to ensure the production efficiency and safety of spent fuel assembly cutting. However, the prediction of wear during the cutting o...
Comparison of longitudinal PSQI and actigraphy-assessed sleep from pregnancy to postpartum
Despite the importance of sleep for perinatal health, there is limited research examining whether different measurement modalities may yield inconsistent data from pregnancy through postpartum. We aim...
Constraints on the source of ions in the Jianhe hot springs in Guizhou Province, China by water-rock interaction experiments
Due to the lack of experimental studies, the effect of water-rock interactions on the hydrochemical characteristics of hot springs within belted reservoir remains poorly understood. To solve this issu...
Psychological richness as a distinct dimension of well-being: Links to mental, social, and physical health
In recent years, well-being research has expanded beyond traditional dimensions, recognizing that a fulfilling life may encompass more than happiness and meaning. We examined the unique contributions...
Cancer disrupts sex hormone-inflammation relationships: Analysis of ALI in males from NHANES 2007–2018
Background To investigate the correlation between sex hormone levels and Advanced Lung Cancer Inflammation Index (ALI) in male cancer populations, and compare with non-cancer male populations, in orde...
Infection prevention knowledge and perceptions: a nationwide survey among nurses and physicians in adult intensive care units in Finland
Background Healthcare-associated infections are a major complication of care for patients in intensive care, causing costs and additional mortality. Infection prevention practices, such as hand hygien...
Text speaks louder: Insights into personality from natural language processing
In recent years, advancements in natural language processing (NLP) have enabled new approaches to personality assessment. This article presents an interdisciplinary investigation that leverages explai...
Improved drug-screening tests of candidate anti-cancer drugs in patient-derived xenografts through use of numerous measures of tumor growth determined in multiple independent laboratories
Background Researchers screen candidate anti-cancer drugs for their ability to inhibit tumor growth in patient-derived xenografts (PDXs). Typically, a single laboratory will use a single measure of tu...
Changes in risk habits and influencing factors in the Taiwan oral cancer screening program
This study examines changes in oral risk habits and identifies factors influencing these changes among participants in a population-based oral cancer screening program to support effective public heal...
Development and validation of context-specific components of obstetric violence: Experiences from the central zone of Tanzania
Background Despite the known consequences of obstetric violence, studies have encountered challenges in defining and fully understanding obstetric violence. This difficulty arises from a relative scar...
Development and evaluation of a training module for people with lived experience of mental illness using social contact strategy for stigma reduction: A study protocol
Social contact strategy or social contact based anti-stigma intervention, where a person with lived experience (PWLE) of mental illness shares his/her lived experiences with the target group, has been...
Incorporating sparse labels into hidden Markov models using weighted likelihoods improves accuracy and interpretability in biologging studies
Ecologists often use a hidden Markov model to decode a latent process, such as a sequence of an animal’s behaviours, from an observed biologging time series. Modern technological devices such as video...
Hidden Markov model for acoustic pesticide exposure detection and hive identification in stingless bees
Pollinator populations are declining globally at an unprecedented rate, driven by factors such as pathogens, habitat loss, climate change, and the widespread application of pesticides. Although colony...
Antenatal identification of early- and late-onset fetal growth restriction and the possible impact of the introduction of cerebroplacental ratio: Effect on perinatal and childhood outcome
Objective To investigate the effect of antenatal identification of small for gestational age (SGA) fetuses on perinatal and childhood outcomes, separately analyzing early- and late-onset fetal growth...
Comprehensive framework for thyroid disorder diagnosis: Integrating advanced feature selection, genetic algorithms, and machine learning for enhanced accuracy and other performance matrices
Thyroid hormones control crucial physiological activities, such as metabolism, oxidative stress, erythropoiesis, thermoregulation, and organ development. Hormonal imbalances may cause serious conditio...
Relationship network, knowledge transfer and open innovation behavior of SMEs from China
In the context of globalization and digital transformation, small and medium-sized enterprises (SMEs) face increasing resource constraints that limit traditional innovation models. This study investig...
Psychological dynamics among Chinese and British negotiators and translators: A text-analytical study of translation manipulation in the English - Chinese translation of the Treaty of Nanking
This paper examines translation manipulation strategies employed by Chinese and British negotiators and translators in the English Chinese translation of the Treaty of Nanking (1842) and explores the...
The Chilean burden of disability-adjusted life years due to cardiovascular diseases: Results from the Global Burden of Disease Study 2021
Cardiovascular disease (CVD) remains a leading cause of death and disability worldwide, including Chile. While mortality rates from CVD are well-documented, the associated burden of disability-adjuste...
Covid-19 in hospitals: Studying influencing factors through agent-based modelling
Hospitals are highly dynamic environments where Covid-19 is highly transmissible if effective measures are not taken. General preventive policies are not necessarily effective; however, agent-based mo...
Protection of LPS-induced intestinal injury in goslings by polysaccharide of Atractylodes macrocephala Koidz based on 16S rRNA and metabolomics analysis
The protective effects of the polysaccharide of Atractylodes macrocephala Koidz (PAMK) against lipopolysaccharide (LPS)-induced intestinal injury in goslings was determined using 16S rRNA analysis of...
The struggle of preserving self-esteem and professional identity: A grounded theory study of specialists’ experiences serving in the public health system in Rajasthan, India
This study aimed to explore and describe the experiences of specialist physicians at rural community health centers (CHCs) and determine the factors accounting for their retention and attrition in Raj...