PLoS ONE
Articles in this Issue
The adverse events of toripalimab in nasopharyngeal carcinoma based on FAERS database and bibliometric analysis
Background Toripalimab, a monoclonal antibody designed to target PD-1, has recently received approval from the U.S. Food and Drug Administration (FDA) for use as a first-line treatment in adults diagn...
Antioxidant properties and antimicrobial activity of selenium nanoparticles synthetized via Zambian medicinal herbs
Previous studies of green synthesized selenium nanoparticles (SeNPs) showed their unique properties such as antibacterial activity, biocompatibility, and antioxidant properties. This study aimed to us...
Mechanism of Plantamajoside in inhibiting ferroptosis of pancreatic β cells and treatment of T2DM via activation of the xCT/GPX4 pathway
Pancreatic β-cell damage, a key pathology in Type 2 Diabetes Mellitus (T2DM), may be mitigated by inhibiting ferroptosis. Plantamajoside (PMS) shows promise in alleviating cellular damage and improvin...
The prevalence of undernutrition and associated risk factors in people with tuberculosis in Lao People’s Democratic Republic
Objective Undernutrition is common in individuals with tuberculosis (TB). There is a bidirectional association between having TB and undernutrition; undernutrition increases the risk of having active...
The effect of viewing-only, reaching, and grasping on size perception in virtual reality
In virtual environments (VEs), distance perception is often inaccurate but can be improved through active engagement, such as walking. While prior research suggests that action planning and execution...
Life cycle assessment of soil carbon dynamics in peach and olive cultivation in Greece: Implementing nature-based solutions
Carbon sequestration is a natural process that removes carbon dioxide from the atmosphere and stores it in plant biomass, soils, oceans, and geological formations- a very important process for reducin...
Cardiovascular risk in aging adults with double deficits in social support: A gender-sensitive, cross-sectional analysis of the CLSA cohort
Background Synergistic effects of diverse social supports (informational, tangible, emotional and belonging) on cardiovascular disease risk factors (CVRF), by gender, is unknown....
Secure mobile agents for efficient medical information retrieval: A verifiable variable threshold secret sharing approach
Mobile Agents are a new type of computing that is replacing the client-server approach. Mobile agents are little pieces of code that function automatically on behalf of the owner. Many applications, s...
Biomechanical risk factors for rotator cuff syndrome in high-risk occupations: A prospective study protocol
Background Rotator cuff syndrome (RCS) is the most common upper limb musculoskeletal disorder worldwide. RCS negatively impacts quality of life and comes with high costs to the individual and society...
Shopping festival atmospherics of China’s singles day shopping festival and participants’ perception: Scale development and validation
China’s Singles Day Shopping Festivals (SDSFs) have continuously attracted consumers in recent years. As large-scale online sales events, their atmospherics have not yet been systematically analyzed....
Cognitive emotion regulation questionnaire: Evidence of internal structure through confirmatory factor modeling and exploratory structural equation modeling
The Cognitive Emotion Regulation Questionnaire is one of the most widely used instruments to measure cognitive emotion regulation, and its psychometric properties have been evaluated in various studie...
Design of Polyether sulfone flat-sheet membranes for multi-layered hemodiafiltration devices
Multilayered hemodialysis devices enable blood flow without the need for an external pump, whereas hollow fiber-type devices require a pump due to significant pressure loss across the fibers. This hig...
The social organization of the Asian weaver ant colonies: A natural enemy novel sub-castes worker’s functional activity findings
An arboreal ant species by nature, the Asian weaver ant Oecophylla smaragdina F., (Hymenoptera: Formicidae) colony’s social structure composition was investigated in depth. Brood and barrack nests wer...
Development of a methodology for measuring the quality of statutory social workers’ complex decision-making
Registered social workers in English Local Authorities are required to have an expertise in the complex decision-making needed to promote well-being when an adult’s own judgement about their well-bein...
TENS alone or combined with low-level laser therapy photobiomodulation for pain, functional capacity, and cardiorespiratory physiological variables after cesarean section: protocol for a randomized clinical trial
Introduction Women undergoing cesarean section frequently report postpartum pain from the surgical procedure, which may be related to functional mobility and cardiorespiratory physiological variables....
Modeling and analysis of 100 kW two-stage three-phase grid-connected PV generation system under absurd atmospheric and grid disturbances
The sustainable growth of renewable energy sources, especially photovoltaic (PV) driven electricity generation, is expected to grow exponentially over the next few years. The extraction of grid parame...
Shedding light on the effects of conflict management training: A multi-rater assessment shines a spotlight on medical students’ skills
Background Medical students are repeatedly exposed to challenging situations while working with healthcare teams, so acquiring conflict management skills is necessary. This study aimed to investigate...
In Silico molecular docking and molecular dynamic simulation of transferrin coated Phenytoin loaded SLNs with molecular targets of epilepsy
Epilepsy is a chronic neurological disorder characterized by recurrent seizures, affecting millions of people worldwide. Phenytoin is a widely used antiepileptic drug, but its therapeutic efficacy is...
Association of pulmonary artery bifurcation angle shift with contralateral stenosis after post-arterial switch in the pediatric transposition of great artery patients
Background The arterial switch operation (ASO) is the standard surgical treatment for transposition of the great arteries (TGA). Postoperative complications such as branch pulmonary artery (PA) stenos...
Nano formulation development and antibacterial activity of cinnamon bark extract-chitosan composites against Burkholderia Glumae the causative agent of Bacterial Panicle Blight in rice
Bacterial panicle blight (BPB) disease, caused by Burkholderia glumae , poses a significant threat to rice production. Conventional chemical control methods con...
Active peptides of TSP-1 inhibit retinal angiogenesis through the CD36 pathway in a rat model of choroidal neovascularization
Background Choroidal neovascularization (CNV) is a key manifestation of intraocular neovascularization, and it is considered one of the main causes of blindness in ophthalmology. Additionally, multipl...
Women’s economic independence and physical intimate partner violence (IPV) during separation
A growing number of studies have addressed the issue of intimate partner violence (IPV). While some studies have shown that women’s economic independence reduces the risk of physical IPV, the empirica...
SARS-CoV-2 survival on skin and its transfer from contaminated surfaces
Understanding the transmission dynamics of SARS-CoV-2, particularly its transfer from contaminated surfaces (fomites) to human skin, is crucial for mitigating the spread of COVID-19. While extensive r...
Desiccation tolerant yet short-lived seeds: A conundrum for post-harvest handling of a high restoration value bunchgrass?
The successful preservation of seeds for future use depends on factors that maintain or limit seed viability. Yet, seed biology knowledge that would facilitate seed storage of most wild species used i...
A systemic approach to accident prevention: How control factors influence accident severity and losses across industries
Accidents are often attributed to frontline operator errors, overshadowing higher-level organizational and regulatory factors. This study integrates Systems-Theoretic Accident Model and Processes (STA...