PLoS ONE
Articles in this Issue
Clinical efficacy and Safety of Baloxavir Marboxil compared with Oseltamivir against influenza virus in children: A systematic review and meta-analysis
Objective Comparing the clinical efficacy and safety of baloxavir marboxil and oseltamivir against influenza viruses in children, to provide theoretical references for clinical practice. Methods A s...
Trends in Myocardial Infarction risk by HIV status in two U.S. healthcare systems
People with HIV have a higher risk of myocardial infarction (MI) compared with people without HIV. Real world evidence on whether the increased burden of MI in people with HIV is sustained over time i...
Adapting COVID-19 research infrastructure to capture influenza and RSV alongside SARS-CoV-2 in UK healthcare workers winter 2022/23: Evaluation of the SIREN Winter Pressures pilot study
Background In winter 2022, SIREN, a prospective healthcare worker cohort study monitoring SARS-CoV-2, ran a pilot sub-study introducing multiplex PCR testing for SARS-CoV-2, influe...
Expression of Concern: Predicting young Chinese consumers’ intentions to purchase Western brands: Structural model analysis
Cloud-native simulation framework for gossip protocol: Modeling and analyzing network dynamics
This research paper explores the implementation of gossip protocols in cloud native framework through network modeling and simulation analysis. Gossip protocol is known for their decentralized and fau...
Households’ expenditures for solid waste management services: Influencing factors and deep insight
This study aims to evaluate the existing solid waste collection and management system available to households in Pakistan and to explore the factors affecting households’ cash payments for waste colle...
Outcomes of complex decongestive therapy in managing upper limb lymphedema in female breast cancer patients at a palliative care unit of a tertiary care hospital in Bangladesh
Background Lymphedema is a chronic condition that significantly affects both physical function and quality of life of breast cancer patients. Although there is no definitive cure, various treatment op...
A study on multi-objective optimization for the location selection of smart underground parking facilities in high-density urban areas of megacities: A case study of Jing’an district, Shanghai
The acceleration of global urbanization and the rapid growth of urban populations have intensified the complexity and urgency of parking demand. In megacities with limited land resources, efficiently...
PPARγ inhibitors enhance the efficacy of statin therapy for steroid-induced osteonecrosis of the femoral head by directly inhibiting apoptosis and indirectly modulating lipoprotein subfractions
Background Steroid-induced osteonecrosis of the femoral head (SONFH) is a serious bone disease commonly seen in patients on long-term glucocorticoid therapy. Although statins have shown some efficacy...
Enhancement of plant growth in lentil (Lens culinaris) under salinity stress by exogenous application or seed priming with salicylic acid and hydrogen peroxide
This study was conducted in order to test the effect of seed pretreatment or exogenous application through the rooting medium of 0.1 mM Salicylic Acid (SA) and 0.1 mM hydrogen peroxide (H2O2) on growt...
Efficient endogenous protein labelling in Dictyostelium using CRISPR/Cas9 knock-in and split fluorescent proteins
Fluorescent protein tagging is a powerful technique for visualising protein dynamics; however, full-length fluorescent protein knock-in can be inefficient at certain genomic loci, making it challengin...
Geography of transnational knowledge flows from China: Distance, Pipelines and Hierarchy?
With the rise of China’s innovation capacity and position in the global innovation system, an increasing number of scholars are paying attention to the knowledge diffusion from developed economies to...
Nicotine alters cellular activity and mRNA expression of patterns of Astrocytes
Nicotine exposure during neural development presents a significant public health concern. Nicotine, the primary addictive component of tobacco, influences the central nervous system by interacting wit...
Correction: SARS-CoV-2 infection in 3,241 School working staffs: Impact of SARS CoV-2 variants of concern [Wild, B.1.1.7 and Omicron]
Proliferation and regeneration of the healthy human urothelium: A multi-scale simulation approach with 16 hypotheses of cell differentiation
The urothelium as a stratified epithelium of the urinary tract is a slow regenerating tissue of different layers and shares similarities with the epidermis. Characteristics of its cell types, regenera...
Visual impairment in any eye adversely affects quality of life: Psychometric validation of the Malay NEI VFQ-25
Purpose To cross-culturally translate and adapt the National Eye Institute Visual Functioning Questionnaire (NEIVFQ-25) into Malay or Bahasa Malaysia, and to analyze its psychometric properties in a c...
Psychological repercussions of breast or uterine cervical cancer disclosure to women in Gabon
Background Breast and cervical cancers are major health issues globally, with particularly high burdens in sub-Saharan Africa, including Gabon. Limited epidemiological data and insufficient attention...
Genetic variability in microbial eukaryotes reshapes marine biodiversity assessment in the age of amplicon sequencing
Rapidly improving DNA sequencing technology has revolutionized our ability to efficiently survey the biodiversity of microbial life. We are now equipped to investigate protistan richness and community...
Time matters: Transcriptomic insights into temporally regulated reproductive and physiological processes in the life cycle of salps
Despite the increasing importance of salps and the recognition of their role as important players in food webs and biogeochemical cycles, their life cycle characteristics and physiology remain mysteri...
NOMO-1 cells expressing an NF-κB luciferase reporter gene facilitate a simple, rapid monocyte activation test that can detect a wide range of pyrogens
Pyrogens, which include endotoxin and non-endotoxin pyrogens (NEPs), act on immune cells in the bloodstream, causing various effects such as fever and endotoxic shock. The limulus amebocyte lysate tes...
Expression of Concern: Real-time recognition of spraying area for UAV sprayers using a deep learning approach
Uncovering common disease mechanisms and critical biomarkers in Crohn’s disease with concurrent psoriasis and exploring potential therapeutic agents
Introduction Research findings show a substantial correlation between Crohn’s disease and psoriasis. However, the exact cause or pathogenesis of the concurrent manifestations of these two conditions i...
Attachment beyond the screen: The influences of demographic factors and parasocial relationships on social media use in Qatar
Background Most studies on social media usage and parasocial relationships (PSRs) have been conducted in WEIRD (Western, Educated, Industrialized, Rich, and Democratic) societies, potentially overlook...
Selective sonochemical post-synthesis modification of LTA zeolite with zinc species
LTA zeolite is known for its straightforward synthesis and well-defined structure, composed of α and β cages. This structure offers a versatile platform for hosting molecules of varying sizes. In the...
The incidence and influencing factors of postoperative acute kidney injury in elderly patients with hip fractures: A meta-analyses
Objective Acute kidney injury (AKI) is one of the common complications after hip fracture in the elderly, and its hospitalization rate, mortality rate and medical expenses are high, resulting in serio...