PLoS ONE
Articles in this Issue
Health insurance enrollment and maternal health service utilization using Ghana Demographic and Health Survey, 2022
Background Maternal health services utilization is essential in the reduction of maternal mortality. Despite the implementation of a national health insurance scheme in 2003, Ghana still reports unive...
Study on static and dynamic performance of aircraft maintenance hangar under multiple load combinations
To analyze the collaborative work performance of the roof structure and the lower support structure for the aircraft maintenance hangar, a numerical model of a single-span aircraft maintenance hangar...
Informal employment, population health, and welfare policies: A global empirical analysis between 2011–2021
Despite informal employment being the most common type of employment globally, the empirical link between informality and health is underexplored. Using time-series, cross sectional data from the Inte...
Cyclodextrin glycosyltransferase immobilization on functionalized graphene nanoplatelets for enhanced cyclodextrin production
Immobilization of enzyme on functionalized nanomaterials offers a promising strategy for enhancing enzyme stability, reusability, and activity in a variety of industrial applications. In this study, g...
Global, regional, and national burden of leukemia: Epidemiological trends analysis from 1990 to 2021
Background: Leukemia is a prevalent form of cancer that encompasses four primary subtypes, posing significant health risks. Gaining insights into the global epidemiology of leukemia and its subtypes i...
Prevalence and incidence of primary autoimmune hemolytic anemia and cold agglutinin disease in the United States, 2016–2023
Background and aims Autoimmune hemolytic anemia (AIHA) and cold agglutinin disease (CAD) are debilitating conditions characterized by chronic hemolysis and severe anemia. The existing epidemiological...
Multi-site validation of an interpretable model to analyze breast masses
An external validation of IAIA-BL—a deep-learning based, inherently interpretable breast lesion malignancy prediction model—was performed on two patient populations: 207 women ages 31 to 96, (425 mamm...
Barriers to referral uptake from primary to secondary eye care in the L V Prasad Eye Institute Network in South India
Purpose To investigate the barriers preventing referral uptake from primary care vision centres (VC) to higher level secondary centres (SC) in rural South India. Methodology This is a cross-sectiona...
Assessing the reliability of abdominal adiposity measurements by transabdominal ultrasound in first trimester pregnancies with sonographers of varying experience levels
Objective Given the growing evidence linking increased abdominal adiposity in early pregnancy to a higher risk of developing gestational diabetes mellitus (GDM), this study aims to evaluate the reliab...
Trends of long-term opioid therapy and subsequent discontinuation among people with chronic non-cancer pain in UK primary care: A retrospective cohort study
Objectives To examine trends of opioid use, focusing on long-term opioid therapy (L-TOT) and its discontinuation among people with chronic non-cancer pain (CNCP)....
Knowledge and stigma of autism spectrum disorders in Chinese university students in the context of inclusive education
This study investigated knowledge of autism spectrum disorder and associated stigma among Chinese university students, utilizing the cross-culturally validated Chinese version of the Autism Stigma and...
Sustained delivery of functional vascular endothelial growth factor from nanoporous silica nanoparticles into a fibrin gel
The unsolved major issue of large-scale tissue engineering scaffolds is insufficient initial vascularization. The lack of oxygen and nutrient supply for migrating cells inevitably leads to cell death...
Splinting in horizontal root fractures: A Bayesian network meta-analysis
Objective This study aims to evaluate which splinting method offers the most favorable prognosis in cases of dental trauma involving horizontal intra-alveolar root fractures. Materials and methods S...
Barriers to cataract surgeries as perceived by visually impaired 50 years and older cataract blind participants of Nepal survey for rapid assessment of avoidable blindness
Purpose To identify the main barriers and determinants to cataract surgery as perceived by 50 years and older Nepali people with severe visual impairment & blind due to cataracts. Methods This w...
Using computer-generated protein models to analyze mutations linked to Amelogenesis Imperfecta
Amelogenesis Imperfecta (AI) is a disorder of tooth development caused by mutations in genes involved in several stages of tooth enamel formation. Few proteins involved in tooth development or develop...
Research on the reliability of the overall structure of submerged radial steel gate
The safety assessment of steel gate structures holds significant social importance and economic advantages. The safety of steel gate structure is influenced by numerous random factors, so it is necess...
Zhuang-Mandarin bilingual children in rural China and the role of grandparental input in early bilingualism
Linguistic properties of bilingual input and their relations with acquisition outcomes are being intensively studied in current research on early bilingual development. Motivated by emerging interests...
Investigating immune amnesia after measles virus infection in two West African countries: A study protocol
“Investigation of Immune Amnesia Following Measles Infection in Select African Regions” (ClinicalTrials.gov Identifier: NCT06153979) is a prospective, observational, longitudinal study being conducted...
Effects of pension eligibility expansion on men’s memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014–2021
Alzheimer’s disease and related dementias (ADRD) are a growing global health concern, with burdens projected to expand rapidly in the coming decades. Since cognitive decline typically precedes ADRD, i...
A crowding free digital interface to help French-speaking children learn to read
Learning to read is a challenging task for first-graders. Letter crowding in the peripheral visual field has been identified as a key interference process during reading acquisition. To reduce crowdin...
The influence of hydrogel stiffness on axonal regeneration after spinal cord injury
The core challenge in spinal cord injury(SCI) treatment is promoting axonal regeneration and forming new neural connections in damaged areas. However, mature CNS neurons have limited regenerative capa...
TLINet: A defects detection method for insulators of overhead transmission lines using partially transformer block
The defects of insulators exhibit characteristics such as complex backgrounds, multi-scale variations, and small object sizes. Therefore, accurately focusing on these defects in dynamic and complex na...
Does darkness increase the risk of certain types of crime? A registered report article
Evidence about the relationship between lighting and crime is mixed. Although a review of evidence found that improved road/ street lighting was associated with reductions in crime, these reductions o...
Paromomycin is a more effective selection agent than kanamycin in Arabidopsis harboring the neomycin phosphotransferase II transgene
Neomycin phosphotransferase II (nptII) is a selectable marker gene that is commonly used in plant molecular genetics and crop improvement, helping researchers to identify and select transgenically mod...
Associations between dietary microbe intake and mortality risk in individuals with sleep disorders: Evidence from NHANES
Objective To investigate the association between dietary microbial intake, sleep patterns, and all-cause and cardiovascular mortality among U.S. adults. Methods This study is conducted using data fr...