PLoS ONE
Articles in this Issue
Optical coherence tomography analysis at initial diagnosis in patients with retinitis pigmentosa and associated cystoid macular edema
This retrospective study analyzed optical coherence tomography (OCT) findings in 130 eyes of 130 patients with retinitis pigmentosa (RP) at initial diagnosis, including 42 with cystoid macular edema (...
Comparative mRNA profile analysis from NAc of adolescent male mice after binge-like alcohol exposure eliciting deficits in context fear extinction learning
Introduction Stressor-related disorders frequently co-occur with alcohol use disorder (AUD). This necessitates an understanding of the physiological and genetic factors contributing to this relationsh...
Correction: Research and application of digital measure management and control technology for characteristic low-efficiency gas wells in Gas Field A
Prevalence of symptom exaggeration among North American independent medical evaluation examinees: A systematic review of observational studies
Background Independent medical evaluations (IMEs) are commonly acquired to provide an assessment of impairment; however, these assessments show poor inter-rater reliability. One potential contributor...
Neural network prediction model based on Levy flight and natural biomimetic technology for its application in cancer prediction
Precise forecasting of cancer outcomes is essential for medical professionals to assess the well-being of patients and develop customized therapeutic plans. Despite its importance, achieving precise f...
Drivers of Lassa fever in an endemic area of southwestern Nigeria (2017–2021): An epidemiological study
Background Reporting two million human Lassa fever (LF) cases with around 10,000 associated annual mortality, the West African sub-region is endemic for Lassa fever virus (LASV). The true incidence of...
Neutralizing monoclonal antibodies improve biodistribution of intravenously administered oncolytic adenovirus in human CD46-transgenic mice
Oncolytic viruses are a unique modality with multifaceted mechanisms of action for killing cancer cells and have been developed as a promising therapeutic approach in cancer treatment. The first-in-cl...
Treatment and control of blood pressure in Welsh patients with and without depression: A study of whole-population electronic health records
Background To explore differences in blood pressure treatment and control in patients with and without depression and a diagnosis of hypertension (HTN). Also to examine the possible impact of sex, soc...
Major adverse cardiac events with haloperidol: A meta-analysis
Background Haloperidol is a commonly used antipsychotic drug and a frequent source of medication safety alerts because of its listing as a “known risk” QT interval-prolonging medication (QTPmed). We a...
Overexpression of MEKK18 from Arabidopsis pumila in rice significantly enhances stress resistance at the early stage
The mitogen-activated protein kinase (MAPK) signaling cascade is a crucial signaling component of eukaryotic cells. It senses endogenous or exogenous stimuli and exerts a critical regulatory influence...
Contemporary eDNA methods complement conventional microscopy in zooplankton diet studies: Case study with American lobster postlarvae
The diets of pelagic marine larvae are difficult to analyze due to their small size and even smaller prey. Furthermore, different methods may lead to alternative interpretations of trophic interaction...
Direct cost of inpatient wound dressing in South West Nigeria: A cross-sectional study
Background Wound dressing is an integral part of wound care protocol. However, the cost of dressing changes with the associated wound aetiology has not been well studied. The study investigates the co...
Effects of attentional focus on the regulation of torque complexity
Recent scientific evidence suggests that an external focus of attention (vs. an internal focus of attention) promotes a greater number of motor solutions, rendering the system more adaptable and compl...
Effects of patient race on processes and experiences of clinical interactions in US emergency departments: A mixed-methods systematic review
Background Evidence shows that patients identified as Black experience worse emergency department (ED) care compared to patients identified as White. Clinical interactions (CI) are thought to affect r...
To hug or not to hug? Public and private displays of affection and relationship satisfaction among people from Indonesia, Nepal, and Poland
Displays of romantic affection, both public and private, contribute to improved well-being, reduced stress, greater life satisfaction, and enhanced relationship satisfaction. However, cultural norms s...
RETRACTED: Edge computing based english translation model using fuzzy semantic optimal control technique
People’s need for English translation is gradually growing in the modern era of technological advancements, and a computer that can comprehend and interpret English is now more crucial than ever. Some...
Evaluation of nerve function after Bell’s palsy based on different facial nerve assessment scales HBGS/SFGS/MPS: A comparative study
Background Studies have shown that approximately 30% of patients with Bell’s palsy may experience permanent disfigurement due to muscle weakness affecting facial expressions. The prognosis for Bell’s...
Influence of mate and nest-site fidelity on a declining, urban avian population
As urbanization reduces species’ habitats and population sizes, managers need information on whether within-population processes, such as changes in mate and nest-site fidelity and dispersal distances...
Left ventricular segmentation method based on optimized UNet and improved CBAM: ESV and EDV tracking study
This paper introduces an optimized nested UNet model for automated left ventricular segmentation in cardiac function assessment. We utilize the EchoNet-Dynamic dataset, which contains both video data...
Associations between genetic HPV 16 diversity and cervical cancer prognosis
Introduction Cervical cancer (CC) arises as a result of chronic and persistent female infection by different oncogenic human papillomaviruses (HPV). The incidence of this disease i...
Investigating the cardiorespiratory fitness gene COX7A2L in cardiomyocytes: Viability and mitochondrial function
Low cardiorespiratory fitness (CRF) is a well-established risk factor for cardiovascular disease (CVD) and all-cause mortality. Since CRF is largely genetically determined, understanding the genetic i...
Diagnostic accuracy of triglyceride to glucose index and triglyceride/high-density lipoprotein index for insulin resistance among children and adolescents: A systematic review
Introduction Insulin resistance (IR) is a common metabolic disorder associated with obesity, type 2 diabetes, and cardiovascular diseases. There is a need for simpler and more cost-effective indices t...
Social capital, digital economy and the entrepreneurship of the new generation of migrant youth: Empirical analysis based on CMDS data
In the era of digital economy, the form of digital production promotes the transformation of enterprise organization and business operation mechanism. It also affects the development of regional entre...
Numerical simulation and parallel implementation of freight train air brake system
Numerical simulations of railway air brake systems are becoming increasingly computationally demanding due to the growing complexity and length of trains. This study introduces a parallel computing-en...
The Human Exersome Initiative (HEI): Rationale, study design, and protocol
Habitual physical activity and exercise training (PA/EX) confers numerous health-benefits. Phenotypic adaptations and clinical health outcomes attributable to PA/EX are well-established, and molecular...