PLoS ONE
Articles in this Issue
Dual-target peripheral and central magnetic stimulation for rehabilitation of chronic pelvic pain syndrome associated with psychosomatic symptoms: Study protocol for a randomized controlled trial
Introduction Chronic pelvic pain syndrome (CPPS) is frequently associated with psychological issues. Repetitive peripheral magnetic stimulation (rPMS) is potentially effective in treating CPPS, while...
Genetic clustering within massive Porites species complex is the primary driver of holobiont assembly
The fate of coral reefs in response to climate change depends on their ability to adapt to new environments. The coral animal is buffered from environmental stress by its algal endosymbionts and micro...
Core outcome sets in symptomatic peripheral artery disease, COS-PAD: Study protocol for developing core outcome sets in symptomatic PAD utilising systematic reviews, interviews, and delphi consensus
Background Symptomatic peripheral artery disease (PAD) presents as intermittent claudication or chronic limb-threatening ischaemia (CLTI). PAD research suffers from wide heterogeneity and non-comparab...
SOX2, PIWI proteins, and MALAT1 – plasma-based emerging biomarkers for cancer detection and monitoring
Background SOX2, PIWI proteins, and MALAT1 are molecular regulators implicated in cancer progression, proliferation, and epithelial-mesenchmal transition (EMT). This study evaluated their expression i...
Influence of renal function and daptomycin dose on clinical effectiveness and adverse events in Japanese pediatric patients: A multicenter retrospective observational study
Background Data on the clinical effectiveness and adverse events of daptomycin in pediatric patients, considering dosage and renal function, are limited. Aim In this study, we aimed to investigate t...
The association between long-term outdoor air pollution exposure and Chinese visceral adiposity index: A nationwide study of middle-aged and older adults
Outdoor air pollutants, particularly particulate matter (PM) and nitrogen dioxide (NO2), have been closely linked to diabetes mellitus, other metabolic disorders, and cardiovascular diseases. Visceral...
Unravelling high insect diversity and community turnover along a tropical-temperate elevation gradient: A metabarcoding approach
The transition zone between the Nearctic and Neotropical biogeographic regions is one of the most species-rich areas of North America, known as the Mexican Transition Zone. We sampled mobile insects a...
Unveiling the link: Evaluating MTHFR gene polymorphisms and colorectal cancer risk through meta-analysis
Colorectal cancer pathogenesis is a multifactorial process, with genetic factors playing a significant role in cancer development. A review of published meta-analyses on MTHFR gene polymorphisms and c...
Nasal vs. oral BREATHing WIn Strategies in healthy individuals during cardiorespiratory Exercise testing (BreathWISE)
Background Nasal and oral exclusive breathing modes have benefits and drawbacks during submaximal exercise. It is less known whether these responses would extend to anaerobic work performed at high in...
Walking cadence as a measure of activity intensity and impact on functional capacity for prefrail and frail older adults
Walking cadence has been suggested as a measure of activity intensity; however, it remains uncertain if prefrail and frail older adults can increase their walking cadence and if doing so leads to impr...
Stakeholder acceptance and attitudes toward dengue prevention: A study on fogging and autocidal traps techniques in Malaysia
The ineffectiveness of current prevention efforts is underscored by the increasing number of dengue cases, emphasizing the necessity of innovative approaches. This investigation investigates the exten...
Surveillance of tuberculosis incidence and mortality through spatio-temporal analysis in Oyo State, Nigeria
The study aimed to describe the epidemiological profile of Tuberculosis (TB) and analyze the spatial distribution and temporal trend of TB incidence and mortality in Oyo state Nigeria from 2015–2019....
Risk factors and incidence of surgical wound infection after stoma reversal: A systematic review and meta-analysis
To determine the incidence and risk factors of incisional infection following stoma reversal surgery. As of July 30, 2024, an extensive literature search was conducted on databases including PubMed, W...
Development and validation of the Self-Awareness of Ego-Threatening Biases Questionnaire (SAETBQ)
Awareness of social biases is crucial as they impact both individual behavior and societal outcomes. Whereas previous research indicates that self-awareness of ego-nonthreatening biases enhances self-...
In-silico trials of targeted screening for abdominal aortic aneurysms using linked healthcare data: A study protocol
Background The NHS abdominal aortic aneurysm (AAA) screening programme (NAAASP) is both clinically and economically effective. One of the main determinants of this effectiveness is disease prevalence....
Chemometric analysis of ethoxylated polymer products using extracted MALDI-TOF-MS peak distribution features
MALDI-TOF MS (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry) of ethoxylate products produces spectra with distributions of regularly spaced peaks resulting from the addi...
Spatio-temporal expansion patterns and influencing factors in China’s new local retail industry: A case study of Luckin Coffee
with the increased penetration of the Internet, artificial intelligence, and other technologies, New Retail, an emerging commercial sector in cities, has gained significant momentum. As a new local re...
MDMA-assisted therapy and current treatment options for chronic, treatment-resistant, moderate or higher severity post-traumatic stress disorder: Systematic literature review
Background 3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) is currently being evaluated for treatment of patients with moderate or higher severity post-traumatic stress disorder (PTSD)....
Incident characterization of health conditions in women suspected of being victims of intimate partner violence
Intimate partner violence (IPV) is a serious public health problem due to its severe health outcomes and its association with significant morbidity and mortality. There are many prevalence studies abo...
Physician perspectives on reducing harm and supporting emergency department patients who use drugs
Background People who use drugs (PWUD) frequently seek care in the emergency department (ED). Little is known about ED physician perspectives and experiences integrating a harm reduction approach into...
Development of a risk prediction model for sepsis-related delirium based on multiple machine learning approaches and an online calculator
Background Sepsis-associated delirium (SAD) occurs due to disruptions in neurotransmission linked to inflammatory responses from infections. It poses significant challenges in clin...
F-TransR: A sports event revenue prediction model integrating multi-modal and time-series data
Sports event revenue prediction is a complex, multimodal task that requires effective integration of diverse data sources. Traditional models struggle to combine real-time data streams with historical...
Retraction: Effect of varying thickness properties of the slow release fertilizer films on morphology, biodegradability, urea release, soil health, and plant growth
Adherence to Iron and Folic Acid Supplementation and its determinants among pregnant women in East Africa: Analysis of Demographic and Health Surveys data from nine East African countries
Introduction Anemia due to deficiency of nutrients like iron and folic acid (IFA) is one of the global public health issues that has contributed to an unacceptably high proportion of maternal and chil...
The role of contributing factors, triggers, and prodromal symptoms in the etiological classification of out-of-hospital cardiac arrest; A scoping review
Background Current Utstein etiological classifications for out-of-hospital cardiac arrest (OHCA) are heterogenous and inaccurate when compared with robust sources. This heterogeneity may influence rep...