PLoS ONE
Articles in this Issue
Accurate full-scale patient-specific Circle of Willis models including aneurysms: A novel manufacturing approach
Background Accurate physical replicas of the Circle of Willis (CoW) are valuable for planning neuroendovascular interventions, validating computational simulations, evaluating medical devices and trai...
Enhanced SVM-based model for predicting cyberspace vulnerabilities: Analyzing the role of user group dynamics and capital influx
Amid substantial capital influx and the rapid evolution of online user groups, the increasing complexity of user behavior poses significant challenges to cybersecurity, particularly in the domain of v...
ATP synthase inhibition, an overlooked confounding factor in the mitochondrial stress test
The mitochondrial stress test, a widely used procedure to study energy metabolism using extracellular flux analysis, involves the inhibition of ATP synthase (a.k.a. complex V [CV]). This inhibition wa...
Skin transcriptomics of invasive Coqui frogs: stress responses, parasite signatures, and antimicrobial peptides
Resilience in amphibians lies in their ecological adaptability, driven by their genetic makeup. Eleutherodactylus coqui, native to Puerto Rico (PR) and a beloved symbol there, is among the most succes...
Is there a “sweet spot” of model complexity for qualitative models used in Ecosystem-Based Management?
Ecosystem models have been developed to help support Ecosystem-Based Management and to help provide better management advice that can account for ecosystem impacts (e.g., climate, species interactions...
Case-control study of maternal and fetal outcomes in beta thalassaemia trait during pregnancy
Individuals with beta thalassaemia trait are not expected to have clinically significant morbidities besides mild anaemia. Pregnancy would exaggerate the anaemia in beta thalassaemia traits, but how t...
Embracing AI in academia: A mixed methods study of nursing students’ and educators’ perspectives on using ChatGPT
Background The integration of artificial intelligence (AI) tools such as ChatGPT is reshaping academic practice, particularly in nursing education. Understanding how nursing students and educators per...
Deciphering the genetic landscape of tomato leaf curl New Delhi virus: Dynamic and region-specific diversity revealed by comprehensive sequence analyses
Tomato leaf curl New Delhi virus (ToLCNDV), a swiftly spreading bipartite begomovirus infecting ~43 plant species across Asia, Africa, and Europe, poses a major agricultural threat. This study compreh...
Risk factors for intraoperative hypothermia during laparoscopic surgery: A systematic review and meta-analysis
Objectives To systematically evaluate the risk factors for intraoperative hypothermia in patients undergoing laparoscopic surgery globally; and to provide information on how to prevent complications a...
Assessing transfusion need in patients with type A aortic dissection with multiplate aggregometry
Background Acute type A aortic dissection (ATAAD) represents a life-threatening surgical emergency. Use of antiplatelet drugs and platelet dysfunction exacerbate the already high rates of postoperativ...
Retraction: Cyclic AMP-response element regulated cell cycle arrests in cancer cells
Ferrocene thiazolidine-2,4-dione derivatives cause DNA damage and interfere with DNA repair in triple-negative breast cancer cells
In this study, ferrocene-containing thiazolidine-2,4-dione derivatives were screened against triple-negative breast cancer (TNBC) cell lines, which represent an aggressive subtype of the disease predo...
Family caregiver role in care recipient preparedness for hospital discharge: A parallel mediation model
Background Family members or friends (caregivers) play a substantial role in supporting health needs of older adults or persons with chronic conditions and accompanying them in acute-care settings. Sc...
Association between depression and health care expenditure in middle-aged and older patients with heart disease
Objective Patients with heart disease frequently experience a heightened incidence of depression, thereby affecting their overall medical expenditures. Nevertheless, earlier investigations have focuse...
Genetic diversity, population structure and quality-trait associations in Blumea balsamifera revealed by EST-SSR markers
Blumea balsamifera is a widely used ancient medicinal herb in tropical and subtropical Asia. Studying the genetic diversity of B. balsamifera germplasm resources and developing molecular markers relat...
Racial and linguistic ideologies and formative assessment practices of U.S. science teachers: A preregistered conceptual replication and extension
Language, race, and racism are deeply connected in the United States and throughout the world. Over the past 10 years, a growing body of research has argued that many language ideologies and racial id...
Digital economy development and global value chain network centralization
The development of the digital economy significantly relies on promoting economic liberalization and achieving high-end embedding of manufacturing into the global value chain (GVC). Based on the heter...
‘The Health-Secure Partnership’: Study protocol for the development of a school- & community-based intervention for promoting healthy nutrition among rural adolescents in The Gambia
Introduction Interventions addressing malnutrition (under- and overnutrition) among adolescents have not been developed in The Gambia. We aim to coproduce the first phase of ‘The Health-Secure Partner...
Addressing food insecurity among U.S. refugees, considering the temporal patterns of food insecurity after resettlement: Qualitative insights from Utah
Background Refugees experience high rates of food insecurity (FI) and its associated health outcomes, such as depression and hypertension. Prior research has identified barriers in accessing food amon...
Sternum drop during trip recovery differs between the laboratory and real world – An exploratory pilot study
The goal of this exploratory study was to compare sternum drop—the decrease in sternum height during an attempt to recover balance after tripping—between lab-induced trips and naturally occurring real...
Consensus on the descriptors, definitions, and reporting methods for heading in football studies: A Delphi study
Heading in football (soccer) is a complex skill involving deliberate head-to-ball contact, which may pose short-, medium-, and long-term risk to player brain health. However, understanding header expo...
Experimental investigation of surface roughness effects on energy harvesting from a piezoelectric eel behind a cylindrical bluff body
Due to dwindling energy reserves and the cost-effectiveness of installation, the global trajectory is shifting towards renewable energy sources as a proficient means of energy acquisition. Among these...
Combination of modified albumin-bilirubin grade and platelet count to predict high-risk varices in patients with hepatocellular carcinoma
Background Variceal bleeding is associated with poor prognosis in patients with hepatocellular carcinoma. Therefore, it is essential to identify indicators of high-risk varices (HRV) and provide promp...
Association between estimated glucose disposal rate and major adverse cardiovascular events in patients with type 2 diabetes
Background Estimated glucose disposal rate (eGDR) is associated with risk of adverse outcomes in patients with type 2 diabetes. However, whether eGDR affects long-term glycemic management in patients...
Prevalence and correlates of metabolic syndrome in patients with initial-treatment and drug-naïve bipolar disorder: A large sample cross-sectional study
Patients with bipolar disorder (BD) are frequently prone to metabolic syndrome (MetS), and their co-morbidity adversely affects patient care outcomes. This study aimed to determine the prevalence of M...