PLoS ONE
Articles in this Issue
Identification of potent antibacterial inhibitors targeting methyltransferase Mtr1/TrmD in Haemophilus influenzae via molecular dynamics simulations
Bacterial influenza is a significant global health and economic concern, and the effectiveness of current therapies is declining as bacterial resistance increases. This case emphasizes the need for no...
The relationship between management practices and health facility performance: Evidence from low-resource, community-based facilities providing HIV services to key populations
Management practices are deemed especially critical to performance in resource-constrained settings. However, empirical evidence is limited for community-based organizations (CBOs) that provide health...
Effects of previous cyclic loading history on subsequent cyclic hehaviour of sand
Sand widely employed as subgrade materials, experience varying traffic-induced cyclic loads during service. This study investigates how prior loading history alters their subsequent cyclic deformation...
Study protocol of a pilot randomized controlled trial of transcranial direct current stimulation paired with reappraisal training for treatment of cannabis use disorder
Introduction As legalization of cannabis products continues, cannabis use becomes more prevalent, and concerns regarding cannabis use disorder (CUD) rise, improving CUD treatment has become increasing...
Effectiveness of first line therapy for Helicobacter pylori infection in children and adolescents: A multicenter study in the United Arab Emirates
Globally, gastric infection with Helicobacter pylori has a high prevalence. Bacterial eradication is crucial to prevent long-term complications such as gastric cancer. There is a standard recommended...
Correction: Clinical efficacy of different methods for treatment of granulomatous lobular mastitis: A systematic review and network meta-analysis
Extending the model of children’s conduct problems: A cross-sectional study of the interaction of maternal temperament and character, maternal parenting practices, and their child’s effortful control
Introduction Children’s externalizing problems in kindergarten are risk-factors that can explain psychopathology at adolescence and adulthood. Hence, it is important to study the complex and multiple-...
Sensing minimal self in sentences involving the speaker
The role of language in the narrative self is well-known, but does it also affect the minimal self? We investigated whether variations in sentence structure affect the speaker’s sense of the minimal s...
Life experiences vs digital inclusion: Factors influencing sense of security and their evolutions in China
Background Digital technology is reshaping and enrich the types of social risks, making the lack of sense of security a widespread phenomenon. The predictors and enhancement strategies for the sense o...
From surviving to thriving: How sleep, physical activity, and diet shape well-being in young adults
Healthy lifestyles are a cornerstone of optimal physical health, yet their contribution to optimal mental health is still an open question. This article investigated the relationships between three ke...
MV2SwimNet: A lightweight transformer-based hybrid model for knee meniscus tears detection
Knee Ailments, such as meniscus injuries, bother millions globally, with research showing that more than 14% of the population above 40 years lives with meniscus-related conditions. Conventional diagn...
A new large hypercarnivorous crocodyliform from the Maastrichtian of Southern Patagonia, Argentina
The first crocodyliform specimen from the Maastrichtian Chorrillo Formation (Austral Basin, Patagonia) is here described. The discovery was made about 30 km to the SW of the town of El Calafate (Provi...
An insight into the gut microbiota of healthy and allergic West Highland Whiter Terrier dogs
Canine atopic dermatitis (cAD) is a multifactorial, genetically predisposed inflammatory skin disease, with a high prevalence in many different dog breeds, with certain breeds being particularly affec...
Editorial Note: Discussing blockchain applications in TED Talks: A fashion wave approach to understanding the blockchain phenomenon
The declining mental health of the young and the global disappearance of the unhappiness hump shape in age
Across many studies subjective well-being has followed a U-shape in age, declining until people reach middle-age, only to rebound subsequently. Ill-being has followed a mirror-imaged hump-shape. Using...
Honey bees bred for Varroa sensitive hygiene trait demonstrate resistance to chalkbrood disease
To improve health and vitality of honey bees (Apis mellifera) beekeepers can propagate stocks that demonstrate resistance to both parasites and pathogens. Most breeding programs focus on resistance to...
Stock market forecasting research based on GA-WOA-LSTM
With the increasing complexity and prosperity of global financial markets, stock market forecasting plays a critical role in investment decision-making, market regulation, and economic planning. This...
The relationship between social support and physical and mental health in an older male population: Evidence from China Health and Retirement Longitudinal Study (CHARLS)
In the context of increasing population aging and decreasing birth rate, it is of great practical significance to explore the impact of social support on the health of elderly men, which is of great p...
Protocol for the isolation and characterization of porcine brain region-associated extracellular particles
Extracellular particles (EPs) are a heterogeneous pool of secreted messengers in cell-cell communication. The isolation of EPs from supernatants, biofluids, and solid tissues allows further research i...
When the hammer drops: Identification of knapping techniques in blade production based on a multi-scale study of knapping traces
As defined by J. Tixier, a knapping technique corresponds to the concrete means used to detach a flake. It involves three essential parameters: the tool(s) used, the mode of force application and the...
Waterpipe-specific pictorial health warning labels are effective in reducing subjective measures, behavioral responses and toxicant exposure among young adults: A crossover study
Background This study aims to assess the impact of six evidence-based Waterpipe (WP)-specific pictorial health warnings (HWs) placed on the WP device on puffing behavior, toxicant exposure, subjective...
Evaluating advance peace in Fresno, California: An interrupted times series analysis of a community-based gun violence intervention
Background Gun violence is a critical public health issue, contributing to the disproportionate burden of health inequities among racially and economically marginalized populations...
Study on the impact and attention of cover papers for PLOS journals: Evidence from propensity score matching
Background Studies on the impact and attention of cover papers within open-access journals from the same publisher remain lacking. The objective of this study was to explore the effect of being featur...
Age and moral disgust: An experimental priming effects vignette study
Disgust influences how people perceive and judge moral violations. Individuals who are more sensitive to disgust often judge such violations more harshly. This sensitivity may change depending on the...
Neurobiological substrates of altered states of consciousness induced by high ventilation breathwork accompanied by music
The popularity of breathwork as a therapeutic tool for psychological distress is rapidly expanding. Breathwork practices that increase ventilatory rate or depth, facilitated by music, can evoke subjec...