PLoS ONE
Articles in this Issue
Synergistic Treatment with Antiretrovirals and Laser Interstitial Thermal ThErapy (STARLITE) for unresectable glioblastoma: A phase 1 study protocol
Glioblastoma (GBM) is the most common form of primary adult brain tumor with a five-year survival of <7%. Standard of care (SoC) involves maximal safe surgical resection with chemoradiation; nevert...
Correction: The Efficient Coding of Speech: Cross-Linguistic Differences
An improved GC-MS-SIM analytical method for determination of pendimethalin residue in commercial crops (leaf and soils) and its validation
Pendimethalin is generally used as pre-emergence herbicide cum suckericide in different growing region of Flue-Cured Verginia (FCV) tobacco by applying indiscriminately in irrigation channel. In quest...
Effectiveness of metaverse-based nursing education on operating room patient safety
Purpose It is speculated that practical education that utilizes the metaverse can reduce the drawbacks of limited practice environments for nursing students and achieve the educational goals of clinic...
Implementation of point-of-care ultrasound in the medical intensive care unit: A retrospective analysis of physician practices and patient outcomes
Background Point of care ultrasound (POCUS) use has become ubiquitous in the ICU setting. Despite this, there remains a paucity of data regarding how its use impacts patient outcomes. We sought to det...
Visualization of multidrug-resistant bacterial infection trends in the intensive care units
Background The Korean National Healthcare–associated Infections Surveillance System (KONIS) monitors multidrug–resistant (MDR) bacterial infections in intensive care units (ICUs). However, simultaneou...
The critical effects of self-management strategies on predicting cancer survivors’ future quality of life and health status using machine learning techniques
Despite the significance of enhancing the quality of life (QoL) and overall health status (including physical, mental, social, and spiritual well-being) among individuals who have survived cancer, the...
Caliban is a transcriptional target of p53 in response to DNA damage
Caliban, the Drosophila ortholog of human Nuclear export mediator factor (NEMF), is a recently identified regulator of the intrinsic apoptotic signaling pathway in response to DNA damage; however, the...
Identifying research priorities for pregnant South Asian immigrants in Canada: A James Lind Alliance approach
Background Pregnant South Asian immigrants (PSAI) make up a significant portion of immigrants to Canada and face a higher risk of adverse pregnancy outcomes compared to other ethnic groups. This dispa...
Incidence, risk factors and outcomes of preterm live births in a tertiary health facility in Ghana
Objectives Accurate measures of the burden of preterm live births are a challenge, particularly in low-and-middle income countries, due to factors including poor data quality and unreliable methods us...
An algorithm for nonlinear problems with variational inequality methods
The purpose of this paper is to introduce a mapping in the framework of a 2-uniformly smooth and uniformly convex Banach space and obtain a common solution for the fixed point set of finite families o...
Exploring the risks of over-reliance on AI in diagnostic pathology. What lessons can be learned to support the training of young pathologists?
The integration of Artificial Intelligence (AI) algorithms into pathology practice presents both opportunities and challenges. Although it can improve accuracy and inter-rater reliability, it is not i...
Evaluation of continuous arrhythmia monitoring using an implantable loop recorder in heart failure patients with a reduced ejection fraction: The LINQ2-HF trial rationale and protocol
Introduction Heart failure with a reduced ejection fraction (HFrEF) is a common and serious condition often associated with atrial fibrillation (AF) and ventricular arrhythmias, leading to poor outcom...
How do patients and health care professionals perceive de-implementation of routine follow-ups after total hip or knee arthroplasty? Protocol for a nested qualitative study within a hybrid effectiveness de-implementation trial
Background Total hip and knee arthroplasties significantly improve the quality of life for patients with severe osteoarthritis. However, some patients experience complications that require follow-up c...
Egalitarian norms can deflate identity-bias link in real-life groups
Social identity theory posits that group membership influences individual behavior by fostering a sense of belonging and promoting normative conformity within groups. While much research has shown a l...
Machine learning driven optimization of compressive strength of 3D printed bio polymer composite material
3D printing has brought significant changes to manufacturing sectors, making it possible to produce intricate, multi-layered designs with greater ease. This study focuses on optimizing the compressive...
Correction: Sentential inference bridging between lexical/grammatical knowledge and text comprehension among native Chinese speakers learning Japanese
Population pharmacokinetic modeling of missed mycophenolate mofetil doses: Impact on exposure and exploration of mitigation strategies
Background Missed doses of mycophenolate mofetil (MMF) are frequent in transplant recipients and may lead to subtherapeutic exposure to mycophenolic acid (MPA), potentially compromising graft function...
Unveiling the gaps: A comprehensive, equity-focused observational examination of Emergency Department discharge
Objectives Prior work has shown that Emergency Department (ED) discharge instructions are often incomplete and poorly comprehended , leading to adverse events. Given the critical importance of effecti...
A qualitative study of graduate student emotional and cognitive processing of unexpected (chance) events
Research on graduate education often focuses on the expected challenges of graduate programs, such as proposal defenses, comprehensive exams, and mentoring relationships. However, less is known about...
Geographic distribution of inflammatory bowel disease in the UK: A spatially explicit survey
Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal (GI) tract, with two main forms: Crohn’s disease (CD) and ulcerative colitis (UC). While CD can affect...
Harnessing the power of hashtags: Temporal pattern mining and storyline construction for event evolution on social media
With the rapid development and wide application of social media, Weibo, as one of the major social media platforms in China, plays an important role in connecting users with information. However, the...
Research on the deformation mechanisms of accumulated landslides induced by different rain patterns based on flume model tests
In the context of intensifying global environmental pressures, heavy rainfall in extreme climate regions significantly increases landslide risks, threatening societal stability and sustainable develop...
Sulfur as a proxy for identifying coast-inland human mobility in Northern Iberia during Late Prehistory
Population movements constitute a significant driver of cultural change in prehistoric societies. In recent years, sulfur isotopes have emerged as a valuable approach for distinguishing human/animal p...
Optimizing ensemble machine learning models for accurate liver disease prediction in healthcare
Liver disease encompasses a range of conditions affecting the liver, including hepatitis, cirrhosis, fatty liver, and liver cancer. It can be caused by infections, alcohol abuse, obesity, or genetic f...