PLoS ONE
Articles in this Issue
Factors associated with stroke recurrence and mortality in ischemic and haemorrhagic stroke: Protocol for a systematic review and meta-analysis
Background and objectives Stroke is one of the leading causes of death and disability worldwide. People with stroke face a significant risk of recurrence, however, there is a lack...
Association between Endothelial Activation and Stress Index and mortality in diabetic nephropathy ICU patients: A retrospective cohort study
Background Diabetic nephropathy (DN) is a serious complication of diabetes mellitus, often leading to poor outcomes in critically ill patients. Endothelial Activation and Stress In...
HPLC-MS profiling and protective potential of the defatted aqueous methanol extract of two Syzygium species against cadmium chloride-induced nephrotoxicity in rats
Cadmium (Cd), a highly toxic heavy metal, is used in food and agricultural products while displaying nephrotoxicity to animals and humans. The genus Syzygium (Myrtle family) is rich in precious phenol...
Kummerowia striata extract protects paracetamol-induced liver injury by modulating the S1P/Nrf2/Keap1 pathway
Background Drug-induced liver injury remains a significant challenge in both drug development and clinical applications. Acetaminophen (APAP), a commonly used analgesic and antipyretic, can cause live...
Weight loss journeys: Exploring social influences and determinants of health in an exploratory rural German intervention
Overweight and obesity are highly prevalent across Western populations and contribute substantially to the global burden of non-communicable diseases such as cardiovascular disease and diabetes. Despi...
Retraction: Food security management in developing countries: Influence of economic factors on their food availability and access
Comparison between wharton’s jelly and collagen natural hydrogels for human ovarian follicle transplantation as an artificial ovary
Artificial ovary (AO) is a bioengineered approach aimed at increasing fertility potential in certain cases, especially in women and prepubertal girls with a history of cancer. Some natural and synthet...
Exploring the association between smartphone-based place visitation data and neighborhood-level coronary heart disease in the United States
Coronary Heart Disease (CHD) is the leading cause of death in the United States, affecting over 20.5 million adults. Previous studies link health behaviors – such as dietary behavior, physical activit...
Dosimetry study of 3D-printed noncoplanar template-assisted CT-guided 125I seed implantation for the treatment of recurrent and metastatic tumors in the head and neck
Objective Recurrent and metastatic tumors of the head and neck pose significant treatment challenges due to their proximity to critical structures and prior...
Exploring the interplay between BMI, subjective body image perception, and health behaviors: A cross-sectional study
Background This study explored the impact of discrepancies between Body Mass Index (BMI) and Subjective Body Image Perception (SBIP) on metabolic health indicators, physical activi...
Evaluating chatbots in psychiatry: Rasch-based insights into clinical knowledge and reasoning
Chatbots are increasingly being recognized as valuable tools for clinical support in psychiatry. This study systematically evaluated the clinical knowledge and reasoning of 27 leading chatbots in psyc...
Resolving Acuticulata (Metridioidea: Enthemonae: Actiniaria), a clade containing many invasive species of sea anemones
Acuticulata is a globally distributed group in the actiniarian superfamily Metridioidea comprised of taxa with ecological, economic, and scientific significance. Prominent members such as...
Seed quality drives grain yield in Ethiopian and Senegalese sorghum: Insights from machine learning
Accurately predicting grain yield remains a major challenge in sorghum breeding, particularly across genetically and geographically diverse germplasm. To address this, we applied a phenotype-informed...
Enhancement of antiphotoaging properties of Cannabis sativa stem water extracts by fermentation with Lacticaseibacillus casei
Skin photoaging, driven primarily by UVB radiation, leads to collagen degradation and oxidative stress, contributing to the visible signs of aging, such as wrinkles and loss of skin elasticity. This p...
Persistence with daily growth hormone among children and adolescents with growth hormone deficiency in Japan
Background Pediatric growth hormone deficiency (pGHD) is treated with daily somatropin (recombinant human growth hormone) injections. High rates of discontinuation and poor adheren...
A new cow identification method using near-infrared spectral measurements and main components of raw milk features
Recent advances in cow identification have been instrumental in enhancing understanding of disease progression, optimizing vaccination strategies, improving production management, ensuring animal trac...
Radiographic criteria in developmental dysplasia of the hip in late infancy, inter and intrareader agreement
Introduction Developmental Dysplasia of the hip (DDH) is a common pediatric disorder screened for by antero-posterior (AP) pelvic radiographs in infants aged between 4–9 months. We chose from the radi...
Hypogonadism and its associated factors among adult male type 2 diabetes mellitus patients at the university of gondar comprehensive specialized hospital, Northwest Ethiopia 2024: A comparative cross-sectional study
Introduction Hypogonadism is an established complication in male patients with type 2 diabetes mellitus, potentially exacerbating metabolic dysregulation and impairing quality of l...
Wear state identification of reciprocating sliding friction Pairs with frictional vibration
Real-time monitoring of the wear state of reciprocating sliding friction pairs has long been a challenging issue. To address this problem, this paper innovatively proposes a new method of constructing...
Filling gaps in PM2.5 time series: A broad evaluation from statistical to advanced neural network models
This study addressed the critical challenge of filling gaps in PM2.5 time series data from Pavlodar, Kazakhstan. We developed and evaluated a comprehensive hierarchy of 46 gap-filling methods across f...
SpaVGN: A hybrid deep learning framework for high-resolution spatial transcriptomics data reconstruction and spatial domain identification
Spatial transcriptomics has revolutionized the analysis of gene expression while preserving tissue spatial information, which provides novel insights into the cellular composition and function of comp...
Nano-polymeric curing agents for enhancing water stability in sandy soils: A sustainable approach for ecological slope protection
The susceptibility of sandy soil slopes to erosion, particularly during rainfall events, poses significant challenges for soil conservation and ecological slope protection. This study explores the pot...
A scoping review of the levels, implementation strategies, enablers, and barriers to cervical, breast, and colorectal cancer screening among migrant populations in selected English-speaking high-income countries
Background Cancer remains one of the leading causes of mortality and morbidity worldwide with colorectal, cervical, and breast cancers accounting for significant proportion of preventable deaths. Earl...
Seroprevalence of antibodies against hepatitis A and E among the general population in 5 provinces, Lao People’s Democratic Republic: Variation according to location
Hepatitis A and E viruses (HAV and HEV) are transmitted through the faecal-oral route: via contaminated food, water, and contact with infected people and/or animals for HEV. Due to limited data from L...
FedNolowe: A normalized loss-based weighted aggregation strategy for robust federated learning in heterogeneous environments
Federated Learning supports collaborative model training across distributed clients while keeping sensitive data decentralized. Still, non-independent and identically distributed data pose challenges...